Laboratory test values at screening outside of the normal range and judged clinically significant by the investigator Out of range laboratory values for measures of hepatic and renal function, electrolytes and blood counts Patient having out of range laboratory values defined as: ) Insufficient bone marrow function at screening: Patient having out of range laboratory values defined as: Patient having out of range laboratory values defined as: Has thyroid function laboratory values within normal range Patient has out of range laboratory values defined as: Patient with any out-of-range laboratory values defined as: Patient having out of range laboratory values defined as: Laboratory values outside the protocol-defined range at screening. Laboratory values not within the protocol-defined range. Patients have out of range laboratory values defined as Patients having out of range values for: Patient with any out-of-range laboratory values defined as: Patient having out of range laboratory values defined as: Hepatic and renal function: Physical and laboratory test findings outside the protocol-defined range.