Able and willing to give informed consent Subject is willing and able to give prior written informed consent for investigation participation; and Willing and able to give informed consent Subjects must be willing to give written informed consent per institutional guidelines and must be able and willing to adhere to dose and visit schedules Willing and able to give informed consent Patient must be willing to give written informed consent and must be able to adhere to dosing and visit schedules, and meet all study requirements. Subjects must be willing to give written informed consent per institutional guidelines and must be able and willing to adhere to dose and visit schedules Be able and willing to give informed consent Patients should be willing and able to give informed consent Patients are willing and able to give informed consent (Phase II only) Willing and able to give informed consent Able and willing to give informed consent. Willing and able to give informed consent Able and willing to give informed consent. Able and willing to give informed consent. ORAL CAVITY SQUAMOUS CELL CARCINOMA COHORT: Willing and able to give informed consent and adhere to protocol therapy Willing and able to give informed consent. Willing and able to give informed consent. Willing and able to give informed consent Subjects must be willing to give written informed consent per institutional guidelines and must be able to adhere to dose and visit schedules Willing and able to give informed consent and adhere to protocol therapy Willing and able to give informed consent Patient must be willing to give written informed consent and must be able to adhere to dosing and visit schedules, and meet all study requirements. Willing and able to give informed consent Willing and able to give informed consent Willing and able to give informed consent Subjects must be willing to give written informed consent and be able to adhere to dose and visit schedules. Able and willing to give informed consent Able and willing to give informed consent Willing to give written informed consent, adhere to the visit schedules and meet study requirements Willing and able to give informed consent and adhere to visit/protocol schedules Subject must be able and willing to give written informed consent for a contrast enhanced ultrasound study of the prostate Patient must be able and willing to give informed consent Willing and able to consent and participate in the study. Willing and able to give informed consent Patients willing to give informed consent