Prior acupuncture treatment within years of enrollment Who are using acupuncture Currently receiving acupuncture for any condition or if they have ever used acupuncture before Upper extremity deformity contralateral to the site of disease that could interfere with accurate point location or alter the energy pathway as defined by traditional acupuncture theory Acupuncture treatment in the preceding weeks prior to day Unwilling to receive acupuncture or unable to travel for treatments Prior use of acupuncture within months prior to the study entry INTERVENTION PHASE: Currently receiving acupuncture treatment for CIPN Upper or lower extremity deformities (ie, missing limbs or scars that prevent needle insertion at the acupuncture points) that could interfere with accurate acupoint location or alter the energy pathway as defined by traditional acupuncture theory Local skin infections at or near the acupuncture sites or are under treatment for active systemic infection History of cerebrovascular accident or spinal cord injury since the mechanism of acupuncture may be associated with central nervous system activity Patients who are currently receiving acupuncture for any condition or if they have ever had acupuncture before Prior use of acupuncture for CIPN within months prior to study entry Patients must have had two or fewer acupuncture treatments within the past months for any reason except for joint symptoms; patients must not have had prior acupuncture treatment for joint symptoms at any time Upper or lower extremity deformities that could interfere with accurate acupoint location or alter the energy pathway as defined by traditional acupuncture theory Local skin infections at or near the acupuncture sites or active systemic infection History of cerebrovascular accident or spinal cord injury since the mechanism of acupuncture may be associated with central nervous system activity Patients who are currently receiving acupuncture for any condition or if they have ever had acupuncture before Ability to complete the or weeks of acupuncture and follow-up assessments Local infection at or near the acupuncture site; (although acupuncture is a minimally invasive procedure, patients will be excluded if there is an indication of infection) Physical deformities that could interfere with accurate acupuncture point location Previous acupuncture treatment for any indication within days of enrollment Previous acupuncture treatment for lymphedema Willingness to comply with all study interventions of acupuncture and follow-up assessments Local infection at or near the acupuncture site (although acupuncture is a minimally invasive procedure, patients will be excluded if there is an indication of infection) Physical deformities that could interfere with accurate acupuncture point location Currently pregnant (certain acupuncture applications have been reported to stimulate uterine contractions) Previous acupuncture treatment for any indication within days of enrollment Have never had acupuncture for xerostomia Active systemic infection or skin infection at or near the acupuncture sites Previous treatment with acupuncture in the last months Dermatological disease within the acupuncture area