New York Heart Association (NYHA) class III or IV heart failure, uncontrollable supraventricular arrhythmias, any history of a ventricular arrhythmia, or other clinical signs of severe cardiac dysfunction
Clinically significant cardiac disease (New York [NY] Heart Association class III or IV), including chronic arrhythmia, or pulmonary disease
Any clinically-significant cardiac disease defined as New York Heart Association class III or IV within the past  months of Screening, unless, in the opinion of the Investigator, the disease is well-controlled
TREATMENT EXCLUSION: Symptomatic cardiac disease (New York Heart Association [NYHA] class III or IV disease)
Adequate cardiac function (?New York Heart Association [NYHA] Class II).
Cardiovascular disability status of New York Heart Association Class greater than or equal to .
Uncontrolled coronary disease or New York Heart Association (NYHA) class III-IV heart disease
Active grade III-V cardiac failure as defined by the New York Heart Association criteria
The patients must not be candidates for chemotherapy due to at least one of the following reasons:\r\n* Performance status of \r\n* Creatinine clearance =<  ml/min as calculated by the Cockcroft-Gault formula\r\n* Cardiac disease such as New York Heart Association (NYHA) class III or IV heart failure or cardiac ischemia within the last  months, grade  or greater neuropathy, or other comorbidities based on which patient is not considered a candidate for chemotherapy
New York Heart Association (NYHA) Class III or IV heart disease, active ischemia or any other uncontrolled cardiac condition, or hypertensive or metabolic condition.
A cardiovascular disability status of New York Heart Association class >= 
New York Heart Association stage  or  cardiac disease.
Cardiac failure New York Heart Association (NYHA) III or IV Crohns disease or ulcerative colitis
Active grade III-V cardiac failure as defined by the New York Heart Association criteria.
New York Heart Association (NYHA) class III or IV heart disease
Active grade III-V cardiac failure as defined by the New York Heart Association criteria.
New York Heart Association (NYHA) functional class =< 
Participant has cardiovascular disability status of New York Heart Association Class >
New York Heart Association stage  or  cardiac disease.
Patients with any of the following cardiac conditions:\r\n* Symptomatic restrictive cardiomyopathy\r\n* Unstable angina within  months prior to enrollment\r\n* New York Heart Association functional class III-IV heart failure on active treatment\r\n* Symptomatic pericardial effusion
A cardiovascular disability status of New York Heart Association class >= 
Major cardiovascular or pulmonary comorbidity that precludes use of general anesthesia (NYHA [New York Heart Association] class III and IV)
Ineligible to receive cisplatin-based neoadjuvant chemotherapy based upon at least one of the following criteria:\r\n* Creatinine clearance <  ml/min \r\n* Eastern Cooperative Oncology Group (ECOG) performance status = \r\n* Grade ?  hearing loss \r\n* Grade ?  neuropathy\r\n* New York Heart Association class III heart failure
New York Heart Association (NYHA) cardiac class - heart disease
Class III/IV cardiovascular disability according to the New York Heart Association Classification
Class III/IV cardiovascular disability according to the New York Heart Association classification
Class III/IV cardiovascular disability according to the New York Heart Association Classification
Patients with moderate to severe heart failure, New York Heart Association (NYHA) class III or IV, liver dysfunction with total bilirubin > . upper limit of normal, or serum creatinine > . mg/dL or any form of dialysis; within  days prior to enrollment
Documented New York Heart Association (NYHA) class I, II and III
Significant cardiac disease (New York Heart Association classes III or IV) or unstable angina despite medication
Cardiovascular disease resulting in New York Heart Association function status of ? .
Clinically significant heart disease, defined as New York Heart Association (NYH) class III or IV
Patients with any of the following cardiac conditions:\r\n* Symptomatic restrictive cardiomyopathy\r\n* Unstable angina within  months prior to enrollment\r\n* New York Heart Association functional class III-IV heart failure on active treatment\r\n* Symptomatic pericardial effusion
Severe cardiac insufficiency (New York Heart Association [NYHA] III or IV), with uncontrolled and/or unstable cardiac or coronary artery disease
New York Heart Association (NYHA) cardiac class - heart disease
Active grade III-V cardiac failure as defined by the New York Heart Association criteria
Patient with active heart disease (New York Heart Association [NYHA] class >=  as assessed by history and physical examination)
Uncontrolled coronary disease or New York Heart Association (NYHA) class III-IV heart disease
New York Heart Association (NYHA) Class III or IV heart failure, uncontrollable supraventricular arrhythmias, any history of a ventricular arrhythmia, or other clinical signs of severe cardiac dysfunction
Clinically stable in New York heart association (NYHA) class  or  for the  months preceding screening Inclusion Criteria for Group 
Cardiac disease, specifically restrictive cardiomyopathy, unstable angina within the last  months prior to enrollment, New York Heart Association functional class III-IV heart failure on active treatment with normalized LVEF on therapy, and symptomatic pericardial effusion
Significant cardiac disease (New York Heart Association classes III or IV) or unstable angina despite medication;
Part : history of have severe cardiac disease (New York Heart Association functional class III or IV)
Documented New York Heart Association (NYHA) class I, II and III
Evidence of New York Heart Association (NYHA) functional class III or IV heart disease
Adequate cardiac functions assessed by  dimensional (D) echocardiography (ECHO).\r\n* (New York Heart Association [NYHA] cardiac III-IV excluded).
Evidence of New York Heart Association (NYHA) functional class III or IV heart disease
Class III/IV cardiovascular disability according to the New York Heart Association Classification
Clinically significant cardiac disease (New York Heart Association, class III or IV)
Clinically significant cardiac disease (New York Heart Association class III/IV) or severe debilitating pulmonary disease
Evidence of New York Heart Association (NYHA) functional class III or IV heart disease
Subjects who have a history or current evidence of uncontrolled cardiovascular disease i.e. NYHA (New York Heart Association) Class III or IV.
Participant has a cardiovascular disability status of New York Heart Association Class greater than .
Normal cardiac function\r\n* No active coronary artery disease\r\n* No New York Heart Association class II, III or IV disease\r\n* No arrhythmia requiring treatment\r\n* Baseline echocardiogram with a shortening fraction of >= % or an ejection fraction >= %
New York Heart Association class III or IV cardiovascular disease
Prior anthracycline treatment and at risk of cardiac failure (New York Heart Association Class )
New York Heart Association Class III or IV heart disease, active ischemia or any other uncontrolled cardiac condition, or hypertensive or metabolic condition
Patients with any of the following cardiac conditions:\r\n* Restrictive cardiomyopathy\r\n* Unstable angina within  months prior to enrollment\r\n* New York Heart Association functional class III-IV heart failure \r\n* Symptomatic pericardial effusion
No previous evidence of class  or greater New York Heart Association cardiac insufficiency or coronary artery disease
Evidence of New York Heart Association (NYHA) functional class III or IV heart disease
Moderate or severe heart disease based on New York Heart Association (NYHA) criteria
Clinically significant cardiac disease (New York [NY] Heart Association class III or IV), including chronic arrhythmias, or pulmonary disease
Patients with New York Heart Association class  or  disease
Clinically significant cardiac disease (New York [NY] Heart Association class III or IV) or pulmonary disease
New York Heart Association (NYHA) class III or IV heart disease
Any of the following cardiac diseases currently or within the last  months as defined by New York Heart Association ([NYHA] Appendix G) ? Class 
Patient with active heart disease (New York Heart Association [NYHA] class greater than or equal to  as assessed by history and physical examination)
Clinically significant cardiac disease (New York Heart Association class III/IV) or severe debilitating pulmonary disease
Clinically significant cardiac disease (New York Heart Association class III/IV) or severe debilitating pulmonary disease
DONOR: History of severe cardiovascular disease, defined as New York Heart Association class III or IV
Class III or IV cardiovascular disease according to the New York Heart Association's (NYHA) Functional Criteria.
No New York Heart Association (NYHA) class III or IV heart disease
Class III or IV cardiovascular disease according to the New York Heart Association's (NYHA) Functional Criteria.
Normal cardiac function:\r\n* No active coronary artery disease\r\n* No New York Heart Association class II, III, or IV disease\r\n* No arrhythmia requiring treatment
Clinically significant heart disease (New York Heart Association [NYHA] class III or IV) within six months
Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease (New York Heart Association functional class III or IV)
Severe cardiac disease (New York Heart Association functional class III or IV) or coronary artery disease
Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease (New York Heart Association functional class III or IV)
Have with history of severe cardiac disease (New York Heart Association functional class III or IV)
Severe cardiac disease (New York Heart Association class III or greater)
New York Heart Association Stage  or  cardiac disease
Severe cardiac insufficiency (New York Heart Association class [NYHA] III or IV), with uncontrolled and/or unstable cardiac or coronary artery disease
New York Heart Association class III/IV cardiac disease
Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease (New York Heart Association functional class III or IV) (PCS study)