Significant screening electrocardiogram (ECG) abnormalities including left bundle branch block, nd degree AV block type II, rd degree block, bradycardia, or corrected QT interval (Fridericias correction; QTcF) >  msec
QTc prolongation (defined as a QTc >  msecs) or other significant ECG abnormalities including nd degree atrioventricular (AV) block type II, rd degree AV block, or bradycardia (ventricular rate less than  beats per minute [bpm]). If the screening ECG has a QTc >  msecs, the ECG can be submitted for a centralized, cardiologic evaluation.
No evidence of PR prolongation or atrioventricular (AV) block on baseline electrocardiogram (ECG)
Other significant electrocardiogram (ECG) abnormalities including nd degree atrio-ventricular (AV) block type II, rd degree AV block, or bradycardia (ventricular rate less than  beats/min)
CRITERIA SPECIFIC FOR COHORT # (MCL): Significant screening electrocardiogram (ECG) abnormalities including, but not limited to, left bundle branch block, nd degree atrioventricular (AV) block type II, rd degree block, or corrected QT interval (QTc) >=  msec; subjects with a cardiac pacemaker who have a QTc interval of >= msec may be eligible if these findings are considered not clinically significant as documented via a cardiology evaluation
Significant screening ECG abnormalities, including unstable cardiac arrhythmia requiring medication, atrial fibrillation/flutter, left bundle branch block, nd-degree atrioventricular (AV) block type II, rd degree AV block, Grade ? bradycardia, or corrected QT (QTc) > msec (for men) or > msec (for women).
Significant screening electrocardiogram (ECG) abnormalities including, but not limited to, left bundle branch block, nd degree atrioventricular (AV) block type II, rd degree block, or corrected QT interval (QTc) >=  msec; subjects with a cardiac pacemaker who have a QTc interval of >=  msec may be eligible if these findings are considered not clinically significant as documented via a cardiology evaluation
Significant screening electrocardiogram (ECG) abnormalities including, but not limited to, left bundle branch block, nd degree atrioventricular (AV) block type II, rd degree block, or corrected QT interval (QTc) >=  msec; subjects with a cardiac pacemaker who have a QTc interval of >=  msec may be eligible if these findings are considered not clinically significant as documented via a cardiology evaluation
Significant screening ECG abnormalities, including unstable cardiac arrhythmia requiring medication, atrial fibrillation/flutter, left bundle-branch block, nd-degree atrioventricular (AV) block type II, rd degree AV block, Grade ? bradycardia, or QT corrected for heart rate (QTc) > msec (for men) or > msec (for women).
Significant screening electrocardiogram (ECG) abnormalities including, but not limited to, left bundle branch block, nd degree atrioventricular (AV) block type II, rd degree block, or corrected QT interval (QTc) >=  msec; subjects with a cardiac pacemaker who have a QTc interval of >=  msec may be eligible if these findings are considered not clinically significant as documented via a cardiology evaluation
Patients with a history of PR prolongation or atrioventricular (AV) block
Other significant electrocardiogram (EKG) abnormalities including second (nd) degree atrio-ventricular (AV) block type II, third (rd) degree AV block, or bradycardia (ventricular rate less than  beats/min)
Relapsed/refractory MCL: Significant screening electrocardiogram (ECG) abnormalities including left bundle branch block, nd degree atrioventricular (AV) block type II, rd degree block, bradycardia (<  beats per minute [bpm]), or corrected QT (QTc) >  msec
Newly diagnosed MCL: Significant screening electrocardiogram (ECG) abnormalities including left bundle branch block, nd degree AV block type II, rd degree block, bradycardia (<  bpm), or QTc >  msec
Patient with evidence of clinically significant bradycardia (heart rate [HR] < ), or a history of clinically significant bradyarrhythmias such as sick sinus syndrome, nd degree atrioventricular (AV) block (Mobitz type ), patient with uncontrolled hypertension (>= / mmHg). Patients who are controlled on antihypertensive medication will be allowed to enter the study
High-grade (second degree or above) atrioventricular (AV) block or persistent sinus bradycardia of less than  beats per minute (BPM)
Significant screening electrocardiogram (ECG) abnormalities including left bundle branch block, nd degree atrioventricular block (AV block) type II, rd degree block, bradycardia (<  beats per minute [bpm]), or corrected QT (QTc) >  msec.
QTcF prolongation defined as a QTcF interval > msec or other significant ECG abnormalities including nd degree (type II) or rd degree AV block or bradycardia (ventricular rate < beats/min).
Significant screening electrocardiogram (ECG) abnormalities including left bundle branch block, nd degree atrioventricular (AV) block, type II AV block, or rd degree block
Significant screening electrocardiogram (ECG) abnormalities including left bundle branch block, nd degree atrioventricular (AV) block, type II AV block, or rd degree block
Other significant electrocardiogram (ECG) abnormalities including nd degree atrio-ventricular (AV) block type II, rd degree AV block
Significant screening ECG abnormalities including left bundle branch block, nd degree AV block type II, rd degree block, Grade  or higher bradycardia, and QTc >  msec.
Significant screening ECG abnormalities including left bundle branch block, nd degree AV block type II, rd degree block, Grade  or higher bradycardia, and QTc ?  ms.
No evidence of second- or third-degree atrioventricular block
First degree atrioventricular (AV) block on ECG in which PR interval lengthened >  milliseconds; second degree; or third degree
Other clinically significant ECG abnormalities including nd degree (Type II) or rd degree atrioventricular (AV) block.
Significant screening electrocardiogram (ECG) abnormalities including left bundle branch block, nd degree atrioventricular (AV) block type II, rd degree block, or corrected QT interval (QTc) >=  msec
First degree atrioventricular (AV) block
Patients with second (nd) or third (rd) degree atrioventricular (AV) block
AV block (other than o AV Block with PR >  msec)
Other significant electrocardiogram (EKG) abnormalities including nd degree atrio-ventricular (AV) block type II, rd degree AV block, or bradycardia (ventricular rate less than  beats/min)
Grade  or  atrioventricular (AV) block (Mobitz type I is permitted) or sick sinus syndrome, unless subject has a pacemaker
Patients must not have history of or presence of Mobitz type II nd degree or rd degree atrioventricular block or sick sinus syndrome, unless patient has a pacemaker
Second (nd) or third (rd) degree heart block as assessed by preoperative electrocardiogram (EKG)
Second- or third-degree atrioventricular (AV) block