No prior malignancy of any type (including ductal breast carcinoma in situ [DCIS]) within the past  years except for current diagnosis of breast cancer, and any prior diagnosis of basal or squamous cell carcinoma of the skin or carcinoma in situ of the cervix; patients with a prior history of breast cancer greater than  years from study screening may participate in this study
No prior history of ipsilateral breast cancer (invasive disease or ductal carcinoma in situ [DCIS]); lobular carcinoma in situ (LCIS) and benign breast disease is allowed
Curatively treated ductal or lobular breast carcinoma in situ and not currently receiving any systemic therapy
Curatively treated ductal carcinoma in situ of the breast.
Presence of lobular carcinoma
History of pleomorphic lobular carcinoma in situ (LCIS), except for participants surgically managed > years prior to diagnosis of current breast cancer
Prior cancer diagnosis except the following:\r\n* Squamous cell cancer of the skin without known metastasis\r\n* Basal cell cancer of the skin without known metastasis\r\n* Carcinoma in situ of the breast (ductal carcinoma in situ [DCIS] or lobular carcinoma in situ [LCIS])\r\n* Carcinoma in situ of the cervix
High grade and/or invasive and/or carcinoma in situ disease
Prior cancer diagnosis, unless the patient has been disease free for >=  years, with the following exceptions:\r\n* Squamous cell cancer of the skin without known metastasis\r\n* Basal cell cancer of the skin without known metastasis\r\n* Carcinoma in situ of the breast (ductal carcinoma in situ [DCIS] or lobular carcinoma in situ [LCIS])\r\n* Carcinoma in situ of the cervix
Patients must be disease-free of prior invasive malignancies for >=  years with the exception of curatively-treated basal cell or squamous cell carcinoma of the skin, carcinoma in situ of the cervix (for phase II only); patients with the following prior or concurrent diagnoses are eligible: lobular carcinoma in situ, contralateral ductal carcinoma in situ, or contralateral invasive ductal and/or lobular cancer (and no prior adjuvant chemotherapy for previous breast malignancy)
INCLUSION - ENROLLMENT: Diagnosis of invasive ductal carcinoma
Prior history of ipsilateral breast cancer (invasive disease or DCIS); lobular carcinoma in situ (LCIS) and benign breast disease is allowed
Subjects must not have invasive lobular carcinoma
For the window phase: Patients must have histologically confirmed invasive lobular carcinoma or invasive ductal carcinoma; no central confirmation of histological subtype is necessary for enrollment; patients with mixed invasive ductal and lobular carcinoma are eligible and will be stratified as ductal
Prior diagnosis of invasive or ductal carcinoma in situ breast cancer in the ipsilateral breast
Prior invasive or in-situ carcinoma of the breast (prior lobular breast carcinoma in situ [LCIS] is eligible)
Any prior diagnosis of invasive or ductal carcinoma in situ breast cancer in either breast
Patients must be disease-free of prior invasive malignancies for >=  years with the exception of curatively-treated basal cell or squamous cell carcinoma of the skin, carcinoma in situ of the cervix; patient with the following prior concurrent diagnoses are eligible: lobular carcinoma in situ, contralateral ductal carcinoma in situ, or contralateral invasive ductal and/or lobular carcinoma
Pathological diagnosis of Invasive Ductal Breast Cancer or Ductal Carcinoma in Situ requiring mastectomy
Active malignancy requiring treatment other than ALL within two years prior to start of treatment, with the exception of basal cell or squamous cell carcinoma of the skin, carcinoma in situ of the cervix, localized prostate cancer, or ductal breast carcinoma in situ (DCIS) or lobular breast carcinoma in situ (LCIS) of the breast
Women with a biopsy proven diagnosis of ductal carcinoma in situ or invasive carcinoma of the breast; biopsy tissue (either slides or block) from outside institutions will be reviewed to confirm diagnosis
Women with a biopsy proven diagnosis of ductal carcinoma in situ or invasive carcinoma of the breast\r\n* Biopsy tissue (either slides or block) from outside institutions will be reviewed to confirm diagnosis
Previously untreated breast cancer determined by a core needle biopsy showing invasive ductal carcinoma or invasive lobular carcinoma
Prior history of other malignancy with the exclusion of localized prostate cancer, non-melanomatous skin cancer, ductal carcinoma or lobular carcinoma in situ of the breast
Ductal carcinoma in-situ with microinvasions (Tmic)
Newly diagnosed stage I to III breast cancer and carcinoma in situ (including lobular carcinoma in situ [LCIS] and ductal carcinoma in situ [DCIS])
Must have pathology proven invasive ductal carcinoma (lobular is not allowed) and/or ductal carcinoma in situ (DCIS).
No prior breast carcinoma or ductal carcinoma in situ in the ipsilateral breast; patients with a local recurrence of a previously excised phyllodes tumor are eligible if the recurrence is in the area of the previous excision
Breast carcinoma or ductal carcinoma in situ in the ipsilateral breast
Ductal carcinoma in-situ or invasive ductal, medullary, papillary, colloid (mucinous), or tubular histologies; invasive lobular carcinomas are allowed
Patients with lobular carcinoma in-situ alone (no invasive component) and patients with non-epithelial breast malignancies such as sarcoma or lymphoma
Women referred for breast conservation surgery following a diagnosis of invasive or in situ carcinoma of the breast by histopathology or women referred for lumpectomy due to a benign (fibroadenoma or papilloma) or high risk breast lesion(Atypical ductal hyperplasia, atypical lobular hyperplasia, lobular carcinoma in-situ, atypical papilloma).
Previously untreated breast cancer determined by a core needle biopsy showing invasive ductal carcinoma or invasive lobular carcinoma
Multicentric invasive or in situ carcinoma
Participants who have another cancer diagnosis, except that the following diagnoses will be allowed:\r\n* Squamous cell cancer of the skin without known metastasis; note, patients with suspected cutaneous squamous cell carcinomas (cuSCCs) should have them excised prior to study registration\r\n* Basal cell cancer of the skin without known metastasis\r\n* Carcinoma in situ of the breast (ductal carcinoma in situ [DCIS] or lobular carcinoma in situ [LCIS])\r\n* Carcinoma in situ of the cervix\r\n* Any cancer without distant metastasis that has been treated successfully, without evidence of recurrence or metastasis for over  years
Presence or history of carcinoma in situ (CIS)
Carcinoma in situ of the breast
Carcinoma in situ of the breast
Carcinoma in situ of the breast
Participants who have received prior anti-cancer therapy for breast cancer except those participants with a history of breast lobular carcinoma in situ (LCIS) that was surgically managed or ductal carcinoma in situ (DCIS) treated exclusively with mastectomy. In case of prior history of LCIS/DCIS, > years must have passed from surgery until diagnosis of current breast cancer
In situ lobular carcinoma or non-epithelial breast malignancies such as sarcoma or lymphoma
Carcinoma in situ (CIS).
Histologic diagnosis of palpable invasive breast cancer or ductal carcinoma in situ
History of previous invasive breast cancer =<  years\r\n* NOTE: history of DCIS, lobular carcinoma in situ (LCIS) is allowed
Ductal breast carcinoma in situ with full surgical resection (i.e., negative margins)
Participants with a past history of ductal carcinoma in situ (DCIS) or lobular carcinoma in situ (LCIS) are not allowed to enter the study if they have received any systemic therapy for its treatment or radiation therapy to the ipsilateral breast (they are allowed to enter the study if treated with surgery alone)
History of any prior (ipsi- or contralateral breast cancer except lobular carcinoma in situ
Prior cancer diagnosis except that the following: \r\n* Squamous cell cancer of the skin without known metastasis\r\n* Basal cell cancer of the skin without known metastasis\r\n* Carcinoma in situ of the breast (ductal carcinoma in situ [DCIS] or lobular carcinoma in situ [LCIS])\r\n* Carcinoma in situ of the cervix\r\n* Any cancer without distant metastasis that has been treated successfully, without evidence of recurrence or metastasis for over  years
Patients with invasive or extensive in-situ lobular carcinoma or non-epithelial breast malignancies such as sarcoma or lymphoma
Participants with a history of previous breast cancer are excluded, with the exception of lobular carcinoma in situ (LCIS) or ductal carcinoma in situ (DCIS) treated by locoregional therapy alone ? years ago. Participants with a history of any other cancer (except non-melanoma skin cancer or carcinoma in situ of the cervix), unless in complete remission with no therapy for a minimum of  years are excluded.
Diagnosis of pathologically-confirmed invasive breast cancer or ductal carcinoma in situ
Carcinoma in situ of the breast
Carcinoma in situ of the breast
History of breast cancer (other than ductal carcinoma in situ [DCIS] or lobular carcinoma in situ [LCIS]) prior to the current diagnosis
history of other invasive malignancy within  years except for cervical carcinoma in situ, nonmelanomatous carcinoma of the skin or ductal carcinoma in situ of the breast that has been surgically cured.
Core needle biopsy (e.g. Mammotome, core, stereotactic, ultrasound guided) showing invasive mammary cancer (with or without concomitant ductal carcinoma or lobular carcinoma in situ) or ductal carcinoma in situ; acceptable histologic types of invasive mammary cancer include ductal, tubular, mucinous, papillary, cribriform and \NOS\ (not otherwise specified); invasive lobular cancer is excluded
Carcinoma in situ of the breast.
Prior history of invasive breast cancer (patients with a history of DCIS or lobular carcinoma in situ [LCIS] are eligible)
Curatively treated ductal carcinoma in situ of the breast;
Any other malignancy active within  years except for non-melanoma skin cancer or carcinoma in situ of the cervix, ductal carcinoma in situ (DCIS) or lobular carcinoma in situ (LCIS) of the breast
Patients with multiple foci of invasive cancer in the same breast are eligible if any single lesion meets the above size criteria and all sampled lesions are histologically similar (whether radiographically detected lesions separate from the target lesion are sampled for histologic evaluation is left to the discretion of the treating physicians); the presence of ductal carcinoma in situ (DCIS) or lobular carcinoma in situ (LCIS) in either breast will not render a patient ineligible; patients with a small focus of invasive cancer detected the contralateral breast (clinical TN) are eligible, however only the histologic response in the breast containing the target lesions will be considered in determining the patients pathologic response
breast carcinoma in situ with full surgical resection
Patients must have a tissue diagnosis of low, intermediate or high grade ductal carcinoma in situ or ductal carcinoma in situ with microinvasion.
Carcinoma in situ of the breast
Histologically confirmed invasive carcinoma of the breast of any of the following histologies (ductal, lobular, mammary, medullary, or tubular); in-situ disease alone is not allowed
No prior history of ipsilateral breast cancer (invasive disease or ductal breast carcinoma in situ [DCIS]); lobular carcinoma in situ (LCIS) and benign breast disease is allowed
Diagnosis of breast or gynecologic cancer, all types (examples are ductal carcinoma in situ [DCIS], lobular carcinoma in situ[LCIS], invasive breast, ovarian, endometrial, vulvar, cervical and vaginal)
Carcinoma in-situ and tumors determined to be T-N
The participant has a -year breast cancer risk .% or lifetime risk of % according to the Gail model; or has a prior diagnosis of lobular carcinoma in situ (LCIS)
Past cancer; patients will be excluded if they have ever been diagnosed with cancer (including ductal breast carcinoma in situ [DCIS]/lobular breast carcinoma in situ [LCIS]) prior to the breast cancer for which the present course of AIs is being prescribed; however, patients will be eligible if their have a history of: nonmetastatic, non-melanotomous skin cancer
History of breast cancer, ductal breast carcinoma in situ (DCIS), or lobular carcinoma in situ (LCIS) (currently without evidence of malignant disease) OR a concern about taking estrogen for fear of breast cancer
Diagnosis of: invasive breast cancer (stage I-III), ductal carcinoma in situ, lobular carcinoma in situ, lobular carcinoma
History of rectal cancer or neoplastic polyp (i.e. intramucosal carcinoma, carcinoma in situ)
Patients must not have previous personal history of breast cancer including ductal carcinoma in situ
Participants with active cancer diagnosis (exception: skin cancer, biopsy-proven atypical lobular, ductal hyperplasia and/or lobular carcinoma in situ)
Have had a prior biopsy diagnosed atypical lobular hyperplasia, atypical ductal hyperplasia, lobular carcinoma in situ, or ductal carcinoma in situ in the last  years; or have had multiple prior breast biopsies, regardless of histology
Patient must have no known breast cancer (DCIS or invasive cancer), not currently undergoing treatment for breast cancer, or planning surgery for a high risk lesion (atypical ductal breast hyperplasia [ADH], atypical lobular breast hyperplasia [ALH], lobular breast carcinoma in situ [LCIS], papilloma, radial scar)
Prior lobular carcinoma in situ (LCIS) is allowed
FOCUS GROUP: No prior breast cancer, invasive or ductal breast carcinoma in situ (DCIS) (ever), no prior lobular breast carcinoma in situ (LCIS) diagnosis, no BRCA mutation carriers or genetic counseling visits
BETA/USABILITY TESTING AND THE TRIAL: Not able to speak and read English; cognitive impairment that precludes informed consent, history of LCIS (lobular carcinoma in situ), prior cancer diagnosis (including DCIS [ductal carcinoma in situ] and invasive breast cancer), known BRCA/ family mutation, or previous receipt of cancer genetic counseling
Participants must be at high risk as defined by a history of breast cancer (invasive or ductal breast carcinoma in situ [DCIS]) and be at least  years out from diagnosis, or lobular carcinoma in situ (LCIS), or proliferative benign breast disease such atypical ductal hyperplasia (ADH), atypical lobular hyperplasia (ALH) or genetic test confirmation of BRCA / mutation carrier or have a breast cancer risk assessment > .% in  years or a lifetime risk > %
At high risk of developing breast cancer (history of ductal carcinoma in situ [DCIS], lobular carcinoma in situ [LCIS], atypical ductal hyperplasia [ADH], Gail  year risk > .% or lifetime risk > %)
Patients referred for risk reduction mastectomy (ex. breast cancer (BRCA) or other high-risk gene mutations, strong family history of breast cancer, history of lobular breast carcinoma in situ (LCIS), atypical ductal breast hyperplasia (ADH), atypical lobular breast hyperplasia (ALH) and those with ductal breast carcinoma in situ (DCIS) undergoing bilateral mastectomy or prophylactic contralateral mastectomy)
A prior biopsy showing lobular carcinoma in situ (LCIS), ductal carcinoma in situ (DCIS), or invasive breast cancer, or individual with breast cancer  or , early onset gene (BRCA/) deleterious mutation
Have history of oral cancer or carcinoma in-situ
Diagnosis of lobular carcinoma in situ (LCIS), atypical ductal, or lobular hyperplasia.
Oral carcinoma in situ
A prior biopsy indicating proliferative breast disease, atypical hyperplasia, ductal carcinoma in situ (DCIS) or lobular carcinoma in situ (LCIS)
Breast carcinoma:
Carcinoma in situ of the breast
Subject must have biopsy-proven invasive ductal carcinoma or ductal carcinoma in situ of the breast
Carcinoma in situ of the breast
Participants must have a history of histologically-confirmed stage I-III invasive breast cancer or ductal carcinoma in situ (DCIS), Pagets disease, lobular carcinoma in situ (LCIS), or proliferative benign breast disease
History of prior breast cancer, ductal carcinoma in situ
Patients with invasive lobular carcinoma
Histologic diagnosis of palpable invasive breast cancer or ductal carcinoma in situ
Histologic diagnosis of invasive breast cancer or ductal carcinoma in situ
History of a non-invasive malignancy, such as cervical cancer in situ, non-melanomatous carcinoma of the skin, in situ melanoma, or ductal carcinoma in situ of the breast, is allowed.
Ductal carcinoma in situ
Prior treatment with radiation therapy to the ipsilateral breast or chest wall\r\n* Prior invasive non-breast malignancy (except non-melanomatous skin cancer, carcinoma in situ of the cervix) unless disease free for a minimum of  years prior to study entry\r\n* Prior invasive or in-situ carcinoma of the breast (-prior lobular breast carcinoma in situ [LCIS] is eligible)\r\n* Diagnosis of ductal breast carcinoma in situ (DCIS)
Have a history of carcinoma-in-situ (CIS)
A primary diagnosis of stage  (ductal carcinoma in situ), , , or a breast cancer