Uncorrected hyponatremia (defined as serum sodium value of < mEq/L) Potassium (K) should be within the range of >= . mEq/L Obtained within days prior to the first dose of cabozantinib: potassium >= . meq/L. Sodium >= mEq/L Hyponatremia (defined as serum sodium level < mEq/L) Anion gap > meq/L or arterial blood pH < .. Potassium > and < . mEq/L Magnesium > . and < . mEq Patients with electrolyte abnormalities at study entry defined as follows: Serum potassium < . mEq/L despite supplementation, or > . mEq/L; Serum magnesium above or below the institutional normal limit despite adequate management; Serum calcium (corrected for albumin levels) above or below institutional normal limit despite adequate management. Serum potassium >= . mEq/L Sodium - mEq/L Potassium .-. mEq/L Bicarbonate - mEq/L Hyponatremia (serum sodium value less than mEq/L) Hyponatremia (defined as serum sodium value of < mEq/L). Uncorrected severe electrolyte disorder, including severe potassium (< . mEq/L) or magnesium (< . mEq/L) deficiency Subjects must have potassium (K+) >. mEq/l. Hyponatremia (defined as serum sodium value of < mEq/L). Serum bicarbonate >= mEq/L Has known renal tubular acidosis with serum bicarbonate < mEq/L Serum potassium >= . mEq/L Serum potassium >= . mEq/L Potassium =< . mEq/L Serum magnesium =< . mEq/L Serum magnesium > .mEq/L Adequate potassium level > . mEq/dL Serum potassium of >= . mEq/L Potassium within the normal range of .-. mEq/L Serum bicarbonate greater than or equal to mEq/L Be either phase advanced or delayed (morning or evening types by the Horne-Ostberg Morningness-Eveningness Questionnaire [MEQ] ? or ? ) Must be either morning or evening types (determined by Horne-Ostberg Morningness-Eveningness Questionnaire [MEQ]) Grade or higher recent (within the past months) or ongoing cardiac dysrhythmias, family history of long QT syndrome, or serum potassium < . mEq/L that is persistent and refractory to correction