Strong CYPA inhibitors: Patients must not have received strong CYPA inhibitors (ciprofloxacin, fluvoxamine, zafirlukast) for at least days prior to enrollment and must not receive them for the duration of the study Patients who require chronic treatment with strong CYPA/ inhibitors =< days prior to registration are not eligible\r\n* NOTE: patients who are currently on treatment with strong CYPA/ inhibitors may be eligible if they are able to be switched to an alternative therapy that is not a strong CYPA/ inhibitor prior to registration on study Concomitant use of strong inhibitors of CYPA known strong CYPA inhibitors . Requires chronic treatment with strong CYPA inhibitors Requires treatment with a strong CYPA/ and/or CYPD inhibitor Strong CYPA inhibitors Requires treatment with strong cytochrome P A (CYPA) inhibitors Newly diagnosed MCL: Requires treatment with strong CYPA/ inhibitors Current treatment with a combination of ibrutinib and strong CYPA inhibitors Requires treatment with strong cytochrome PA (CYPA) inhibitors. requires treatment with strong CYPA inhibitors Requires treatment with strong CYPA inhibitors Exclusion Criteria for Phase Sub-study Cohort: Requires treatment with strong CYPA inhibitors Requires chronic treatment with strong CYPA inhibitors; if patients have been on a strong CYPA inhibitor in the past, they will not be eligible if the CYPA inhibitor was administered within days of the first dose of study drug Requires treatment with strong cytochrome P A (CYPA) inhibitors Requires treatment with strong CYPA inhibitors Requires treatment with strong CYPA inhibitors Concomitant use of strong CYPA inhibitors Participants who are taking strong CYPA inhibitors Requires treatment with strong cytochrome (CYPA/) inhibitors strong CYPA inhibitors, or Subjects currently taking medications known to be strong CYPA inhibitors. Subjects taking or likely to take strong and moderate CYPD inhibitors, strong CYPA inhibitors, and/or CYPA/CYPA sensitive substrates or with narrow therapeutic index. Subjects receiving oral BAY and IV docetaxel must not take or be likely to take strong CYPA inhibitors The subject requires chronic concomitant treatment of strong CYPA inhibitors Requires treatment with strong CYPA inhibitors. Strong Inhibitors of CYPD Patients requiring chronic treatment with strong CYPA inhibitors Patient requires treatment with strong CYPA inhibitors or moderate or strong CYPA inducers other than those required for GVH or infection prophylaxis or treatment