Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patients current disease state must be one for which there is not known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patients must have relapsed or refractory cancers for which there is no known curative option or other available therapy proven to prolong survival with an acceptable quality of life Patients with diagnosis of solid tumor with lung metastases and patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life; for patients in whom surgery is feasible, maximal surgical resection must have occurred Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patient's current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life. Current disease state must be one for which there is currently no known curative therapy or no additional therapies proven to prolong survival with an acceptable quality of life. Therapeutic options: Participant's current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life. PRE-REGISTRATION: Patients with relapsed or refractory solid tumors and without known curative therapy or therapy proven to proven to prolong survival with acceptable quality of life. Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Therapeutic options: patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life Must have a disease that is relapsed/refractory to all potentially curative standard treatment regimens or must have a current disease for which there is no known curative therapy, or therapy proven to prolong survival with an acceptable quality of life. Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life