History of connective tissue disorders (eg, lupus, scleroderma, arteritis nodosa). Bilateral hip prostheses, inflammatory bowel disease or connective tissue disorder such as active scleroderma or lupus (radiotherapy contraindications) History of connective tissue disorders such as rheumatoid arthritis, lupus, or Sjogrens disease Active connective tissue disorders, such as lupus or scleroderma that in the opinion of the treating physician may put the patient at high risk for radiation toxicity; Subjects with a history of connective tissue disorders. Patients who have a history scleroderma or other active connective tissue disease Active connective tissue disorders, such as lupus or scleroderma, that in the opinion of the treating physician may put the patient at high risk for radiation toxicity History of active connective tissue disease (scleroderma) History of active connective tissue disease (scleroderma) or idiopathic pulmonary fibrosis History of an active connective tissue disorder Any patient with active connective tissue disease such as lupus, dermatomyositis Scleroderma or active connective tissue disease Active connective tissue disorders, such as lupus or scleroderma Active connective tissue disorders, such as lupus or scleroderma, which in the opinion of the treating physician may put the patient at high risk for immunologic toxicity Current treatment for active connective tissue disorders, such as lupus or scleroderma Active connective tissue disorders, such as lupus or scleroderma, that in the opinion of the treating physician may put the patient at high risk for radiation toxicity Active connective tissue disease Active connective tissue disorders, such as lupus or scleroderma History of connective tissue disorders such as rheumatoid arthritis, lupus, or Sjogrens disease Scleroderma or active connective tissue disease History of connective tissue disorders (eg, lupus, scleroderma, arteritis nodosa). Any patient with active connective tissue disease such as lupus, dermatomyositis Connective tissue disorders, e.g. scleroderma, that in the opinion of the treating physicians is a contraindication to radiation therapy Patients with connective tissue disorders specifically systemic lupus erythematosus, scleroderma, or dermatomyositis Patients with a known connective tissue disease Co-morbid systemic illnesses or other severe concurrent disease which, in the judgment of the investigator, would interfere significantly with whole-breast irradiation (such as connective tissue disorders, lupus, or scleroderma)