Unable or unwilling to swallow napabucasin capsules daily. Unable or unwilling to swallow napabucasin capsules daily. Unable or unwilling to swallow the complete daily dose of ARQ Unable or unwilling to swallow BBI and/or BBI capsules daily Prior treatment with either BBI or BBI Unable or unwilling to swallow BBI capsules daily. Unable or unwilling to swallow BBI capsules daily Unable or unwilling to swallow BBI capsules daily. Unable or unwilling to swallow BBI capsules daily Unable or unwilling to swallow BBI capsules daily. Unable or unwilling to swallow the complete daily dose of ARQ Unable or unwilling to swallow the complete daily dose of ARQ capsules Unable or unwilling to swallow BBI/placebo capsules daily. Unable or unwilling to swallow BBI, BBI, or sorafenib capsules or tablets Unable or unwilling to swallow BBI capsules daily