Previous exposure or known allergy to Imprime PGG or any of its excipients Patients who have previously received PGG-Betafectin (Betafectin) or Imprime PGG Had previous exposure to Betafectin or Imprime PGG Had previous exposure to Betafectin or Imprime PGG Has had previous exposure to Betafectin or Imprime PGG;