No treatment with any other type of investigational agent =< weeks before pre-registration No treatment with biologic therapy, immunotherapy, chemotherapy, investigational agent for malignancy, or radiation =< days before study registration; no treatment with nitrosourea or mitomycin =< days before study registration; for GIST, tyrosine kinase inhibitor can be continued for up to days prior to initiation of study treatment No treatment with immunotherapy =< days before re-registration; no treatment with biologic therapy, chemotherapy, investigational agent for malignancy, or radiation =< days before re-registration; no treatment with nitrosourea or mitomycin =< days before re-registration No treatment with biological therapy, immunotherapy, chemotherapy, investigational agent for malignancy, or radiation =< days before study registration; no treatment with nitrosourea or mitomycin =< days before study registration No investigational agent within days prior to registration No investigational therapy within days prior to registration Patients must not have any anticancer therapy or investigational agent within days prior to step registration Treatment with any investigational agent within days prior to registration for protocol therapy Other investigational treatment during or within days before starting study registration Subjects on treatment with chemotherapy or any investigational therapeutic agent will need to discontinue therapy weeks prior to registration (wash out period) Treatment with any therapeutic investigational agent within days prior to study registration. Patients must not have received treatment with any chemotherapy, immunotherapy, radiotherapy or an investigational agent for malignancy within the days preceding study registration; patients may not have received treatment with nitrosoureas or mitomycin within the days prior to study registration; patients may not have received treatment with a small molecule targeted agent (including off-label or investigational use) within days preceding study registration, provided this represents at least half-lives for that agent; toxic effects from any prior therapy (except alopecia) must have resolved to grade or less according to National Cancer Institute (NCI) CTCAE version (v). or to the patients baseline by the time of registration Treatment with an investigational agent within weeks of registration Treatment with any investigational agent within days prior to being registered for protocol therapy No treatment with any investigational agent for any medical condition within days prior to being registered for protocol therapy Treatment with any investigational agent or on an interventional clinical trial within days prior to treatment on protocol Treatment with any investigational agent or on an interventional clinical trial within days prior to registration No treatment with any investigational agent within days prior to being registered for protocol therapy No treatment with any investigational agent within days prior to registration for protocol therapy Any other investigational agent or used an investigational device within days prior to day of protocol therapy Treatment with any investigational agent within days prior to registration for protocol therapy No treatment with biologic therapy, immunotherapy, chemotherapy, investigational agent for malignancy, or radiation =< days before study registration; no treatment with nitrosourea or mitomycin =< days before study registration Treatment with any investigational agent within days prior to registration for protocol therapy Treatment with any investigational agent within days prior to being registered for protocol therapy Prior treatment with any other agent that may affect M-protein =< days prior to registration Use of an investigational agent within the previous days of study registration Treatment with any other investigational agent within days prior to registration. Subjects must not be treated with any other investigational agent while on protocol specified therapy. No treatment with any investigational agent within days prior to registration for protocol therapy. Investigational agent within days prior to day of protocol therapy Treatment with any investigational agent within days prior to registration for protocol therapy Subjects must have received their last dose of investigational or biologic agent >= days prior to study registration\r\n* In the event that a subject has received an investigational or biologic agent and has experienced >= grade myelosuppression, then at least three () weeks must have elapsed prior to registration\r\n* If the investigational or biologic agent has a prolonged half-life (>= days) then at least three () weeks must have elapsed prior to registration No treatment with any investigational agent within days prior to study registration. Treatment with any investigational agent within days prior to being registered for protocol therapy Treatment with any investigational agent within days prior to registration. Any investigational agent is acceptable if administered >= days before registration No treatment with any investigational agent within days prior to registration for protocol therapy. NOTE: If treated with investigational agent within days prior to registration, AE must be resolved back to baseline. Treatment with any investigational agent within days prior to registration for protocol therapy Administration of any investigational agent =< days prior to pre-registration