Osteoporosis (T-score of less than -. by DEXA scan)
Subjects with history of osteoporosis
Women with severe bone density issues/osteoporosis (defined as any medical treatment for osteoporosis, and/or a T-score of -. or lower, and/or history of fracture of the hip or spine)
Pts w/ osteopenia (T-score of - to -. at L/R total hip, L/R femoral neck or lumbar spine [L-L]) eligible
Bisphosphonate therapy (osteoporosis or symptomatic hypercalcaemia) or denosumab (osteoporosis) prior to study drug
Osteoporosis (T-score of <?. at L/R total hip, L/R femoral neck, or lumbar spine [L-L] by DEXA scan)
Prior use of osteoclast inhibitors for osteoporosis will not be allowed
Osteoporosis, defined as T-score less than -.
Known history of osteoporosis
Osteoporosis complicated by pathologic fracture
Osteoporosis based on a T-score of <-. at the left or right total hip, left or right femoral neck or lumbar spine (L-L) as determined by DEXA scan
Osteoporosis based on a T-score of <-. at the left or right total hip, left or right femoral neck or lumbar spine (L-L) as determined by DEXA scan
Osteoporosis based on a T-score of <-. at the left or right total hip, left or right femoral neck or lumbar spine (L-L) as determined by DEXA scan
Osteoporosis based on a T-score of <-. at the left or right total hip, left or right femoral neck or lumbar spine (L-L) as determined by DEXA scan
Patients with known osteopenia or osteoporosis.
Diagnosis of osteoporosis
History of severe osteoporosis (T score =< - either spine or hip), or presence of vertebral fracture
Diagnosed with osteoporosis
Severe osteoporosis
Women with known osteoporosis or history of osteoporotic (fragility) fracture of the spine
Osteoporosis: patients with a history of fragility fracture, or a hip or spine T score of < -. (these patients will be treated with zoledronic acid and followed, but excluded from randomization)