Are willing and able to provide signed informed consent. Willing and able to provide informed consent. Must be able and willing to participate in all aspects of the study and provide informed consent prior to study participation. Willing and able to provide informed consent Able to provide informed consent and be willing to participate in study schedule and events. Willing and able to provide informed consent Willing and able to provide informed consent Willing and able to provide consent Willing and able to provide consent Patient able and willing to provide informed consent. Willing and able to provide informed consent All patients must be willing and capable to provide informed consent to participate in the protocol All patients must be willing and capable to provide informed consent to participate in the protocol Able and willing to provide informed consent All patients must be willing and capable to provide informed consent to participate in the protocol Able and willing to provide consent for required bone marrow biopsies. Willing and able to provide informed consent DONOR: Willing and able to provide informed consent All patients must be willing and capable to provide informed consent to participate in the protocol Willing and able to provide informed consent COHORT A: The subject must be willing and able to provide informed consent COHORT B: The subject must be willing and able to provide informed consent Able to provide informed consent and be willing to sign an informed consent form Willing and able to provide informed consent All patients must be willing and capable to provide informed consent to participate in the protocol Patients must be willing and able to provide signed informed consent and comply with the study protocol. Patient or guardian willing and able to provide informed consent. Willing and able to provide informed consent At least years of age and willing and able to provide informed consent. Willing and able to provide informed consent Willing and able to provide informed consent; Willing and able to provide informed consent Age years or older and willing and able to provide informed consent; PROVIDER ELIGIBILITY: The participant is willing to provide informed consent in English Able and willing to provide informed consent Willing and able to provide informed consent Willing and able to provide informed consent Not willing and able to provide informed consent Capable and willing to provide Informed consent Willing and able to provide informed consent Not willing and able to provide informed consent Willing and able to provide signed, informed consent Able and willing to provide consent (both) PATIENT: Be able and willing to provide informed consent Able and willing to provide informed consent Willing and able to provide, signed informed consent The subject must be willing and able to provide informed consent Cognitively able and willing to provide consent Subjects willing and able to provide consent to participating in the study Able to understand and willing to provide informed consent for the RPFNAs and study participation Patients who are willing and capable to provide informed consent Capable and willing to provide informed consent The patient is willing and able to provide informed consent. Patients must be capable and willing to provide informed consent Patients must be capable and willing to provide informed consent. Patient able and willing to provide informed consent HCC PATIENTS: Patient is willing to provide informed consent The patient must be willing and able to provide informed consent Willing and able to provide informed consent Be willing and able to provide informed consent NORMAL VOLUNTEERS: Be willing and able to provide informed consent Participants must be willing to participate and provide signed informed consent Willing and able to provide informed consent and fill out demographic, disease, and pain assessment questionnaires