Dementia of any kind
Active infection of any kind.
Prior systemic treatment of any kind or radiotherapy for RCC
Two prior stem cell transplants of any kind.
Clinically relevant infection of any kind within the month preceding enrollment (example, active hepatitis C, pneumonia)
Immunosuppression, of any kind
Patients with prior transplant of any kind are not eligible
Requirement for immediate palliative treatment of any kind including surgery
No requirement for immediate palliative treatment of any kind including surgery
Requirement for immediate palliative treatment of any kind including surgery
Requirement for immediate palliative treatment of any kind including surgery
Requirement for immediate palliative treatment of any kind including surgery
Requirement for immediate palliative treatment of any kind including surgery
Requirement for immediate palliative treatment of any kind including surgery
Two prior stem cell transplants of any kind
Clinically relevant infection of any kind within the month preceding enrollment (eg, active hepatitis C, pneumonia)
Clinically relevant infection of any kind within the preceding month of enrollment
Requirement for immediate palliative treatment of any kind including surgery
disease recurrence either must occur within  months of the most recent intravesical therapy of any kind, OR
Prior radiation therapy of any kind is allowed.
Use of investigational agents of any kind within  days before study treatment
Prior allogeneic transplant of any kind
Requirement for immediate palliative treatment of any kind including surgery
Requirement for immediate palliative treatment of any kind including surgery
Requirement for immediate palliative treatment of any kind including surgery
Prior radiation therapy of any kind is allowed
Two prior stem cell transplants of any kind
Requirement for immediate palliative treatment of any kind including surgery
Systemic investigational drug of any kind within  weeks of AVB- administration
Prior treatment of any kind for this malignancy
Anti-tumor therapy of any kind or major surgery within  weeks prior to Day .
Prior therapies: Patients undergoing stem cell transplant of any kind
Metastatic malignancy of any kind
Metastatic malignancy of any kind
Concurrent cancer treatment of any kind is allowed, but the participant can also have completed all treatment
Metastatic disease of any kind
Taking nitrates of any kind
Metastatic malignancy of any kind
Other current malignancy or metastatic malignancy of any kind