Received prior radiotherapy to any portion of the abdominal cavity or pelvis
Patients who are not candidates for major abdominal surgery due to known medical comorbidities
Prior intra-abdominal surgery within  weeks of trial enrollment.
Patients with extra-abdominal metastatic disease
Patients who have had prior abdominal radiotherapy
Subjects who have received prior radiotherapy to any portion of the abdominal cavity or pelvis are excluded
Prior radiation to the liver or other upper abdominal regions
Known or suspected extensive abdominal adhesions
Prior radiotherapy to any portion of the abdominal cavity or pelvis
Patients must be reasonable candidates for laparoscopy and IP platinum regimen with no prior evidence of clinically significant intra-abdominal adhesions, persistent abdominal wall infections, renal toxicity, or bowel obstruction
Prior abdominal radiotherapy
Prior history of abdominal radiation therapy
Patients with prior radiation to the abdominal cavity or pelvis are excluded
Subjects received previous abdominal radiation
Intra-abdominal disease >  cm in diameter at the time of registration, intrahepatic disease, or disease beyond the abdominal cavity; patients with intra-abdominal lymph node involvement are eligible based on biodistribution data indicating viral dissemination to lymph nodes following intraperitoneal administration
Prior history of abdominal radiation therapy
No prior abdominal radiation
Primary or recurrent retroperitoneal or abdominal tumor
Radiologic workup must demonstrate that the disease is confined to the abdominal cavity and/or is not metabolically active on PET (positron emission tomography scan), outside of the abdominal cavity
Patients will be ineligible if they have disease outside of the abdominal cavity which is uncontrolled or PET avid
Recent (i.e., ?  weeks) history of abdominal surgery or peritonitis
Received prior radiotherapy to any portion of the abdominal cavity or pelvis.
Received prior chemotherapy for any abdominal or pelvic tumor.
Patients who have received prior radiotherapy to any portion of the abdominal cavity or pelvis are excluded
Subject with an active abdominal or pelvic infection at the operation site.
Patient must be eligible for abdominal surgery
Emergency surgery for abdominal indications
Radiologic workup must demonstrate that the disease is confined to the abdominal cavity and/or is controlled outside of the abdominal cavity
Patients will be ineligible if they have disease outside of the abdominal cavity which is uncontrolled
Patients who have had prior abdominal radiotherapy
Patients with prior abdominal surgery within  days prior to entering the study
Patients with liver metastases cannot have received prior upper abdominal radiation
Patients who have received previous abdominal radiation
Patients who have had prior abdominal radiotherapy
Recurrent and/or metastatic resectable colorectal cancer, including disease within the abdomen and pelvis with no evidence of extra-abdominal metastases; intra-abdominal disease includes: isolated hepatic metastasis/metastases (see next inclusion criteria point), isolated peritoneal metastasis, or a combination of hepatic and extrahepatic metastasis
Prior abdominal radiotherapy
Large pelvic or intra-abdominal masses
History of abdominal surgery precluding free flap donor site
Patients undergoing anterior abdominal wall hernia repairs
Prior abdominal or pelvic RT
Physiologic suitability for major abdominal surgery
Pfannenstiel or transverse abdominal incision
Patients with prior abdominal or pelvic surgery
Major abdominal or pelvic surgery within the past  months