Any other radiotherapy or radionuclide require -day washout prior to first dose of study drug The participant has received radionuclide treatment within weeks of the first dose of study treatment Radionuclide treatment within weeks of the first dose of study drug in this study mCRPC EXPANSION COHORT: The patient has received radionuclide treatment within weeks prior to the first dose of the study treatment Received radionuclide treatment (i.e. iodine [I]- meta-iodo-benzyl guanidine) within months of the first dose of study treatment The subject has received radionuclide treatment within weeks of the first dose of study treatment The subject has received radionuclide treatment within weeks of the first dose of study treatment The subject has received radionuclide treatment within weeks of the first dose of study treatment No prior radionuclide treatment within weeks of the first dose of study treatment Radionuclide treatment, including yttrium- treatment, within weeks of the first dose of study treatment The subject has received radionuclide treatment within weeks before the first dose of study treatment Systemic therapeutic radionuclide delivery within days prior to treatment The subject has received radionuclide treatment within weeks prior to the first dose of the study treatment Biological agents (antibodies, immune modulators, cytokines, or vaccines) or radionuclide treatment within weeks of the first dose of study treatment The participant has received radionuclide treatment within weeks of the first dose of study treatment Cannot have received radionuclide treatment within weeks of first dose of study treatment The subject has received radionuclide treatment within weeks of the first dose of study treatment The subject has received radionuclide treatment within weeks of the first dose of study treatment The subject has received radionuclide treatment within weeks of the first dose of study treatment The subject has received radionuclide treatment within weeks of the first dose of study treatment Major surgery or other loco regional treatment within weeks before the first dose of study drug or radionuclide treatment within weeks