Splenic irradiation within the last  months
History of prior or current splenectomy or splenic irradiation
Splenic irradiation within  months prior to screening, or prior splenectomy.
History of or current immunodeficiency disease, splenectomy or splenic irradiation
Splenic irradiation within  months prior to the first dose of study drug
History of or plan for splenectomy or splenic irradiation
Splenic irradiation within  months prior to Randomization
Splenic irradiation  months prior to enrollment.
At least  months from prior splenic irradiation
History of or current immunodeficiency disease (e.g. splenectomy or splenic irradiation)
Splenic irradiation within  months prior to the first dose of MMB
Phase  Part: Patients who have had prior splenectomy or have had splenic irradiation within  months of starting study drug