Patients with serum creatinine > . mg/dL and patients on active dialysis for renal dysfunction are excluded Renal failure requiring hemo-or peritoneal dialysis Dialysis dependent renal failure Renal failure requiring hemo- or peritoneal dialysis Renal failure requiring hemo-or peritoneal dialysis Renal failure requiring hemo-or peritoneal dialysis Current use of a non-standard dialysis membrane Patients on dialysis within days of enrollment. Research participant requires dialysis Has a history of, or is currently on, dialysis. Renal failure requiring hemo-or peritoneal dialysis Renal failure requiring hemo-or peritoneal dialysis Subject is currently on renal dialysis Patients with renal failure currently requiring dialysis of any kind are not eligible Patients on dialysis Serum creatinine (Cr) > mg/dL, dialysis, or prior renal transplant Research participant requires dialysis Renal failure requiring hemo- or peritoneal dialysis Requiring renal dialysis Patients on dialysis Renal insufficiency requiring dialysis Renal failure requiring hemo-or peritoneal dialysis Renal failure requiring hemo-or peritoneal dialysis Patients undergoing renal dialysis. Patients on dialysis. Have stable renal function without dialysis for at least months prior to Investigational Product (IP) administration defined by: current or prior dialysis, current or prior dialysis, Renal failure requiring hemo-or peritoneal dialysis Renal failure requiring hemo-or peritoneal dialysis Renal failure requiring hematological (hemo-) or peritoneal dialysis Renal failure (on dialysis) Renal failure requiring hemo-or peritoneal dialysis Renal failure requiring hemo- or peritoneal dialysis Lack of acute renal failure/requirement for dialysis, as evidenced by creatinine < . mg/dL Renal failure requiring hemo- or peritoneal dialysis Subjects with severe renal impairment requiring dialysis. Renal failure requiring hemo- or peritoneal dialysis History of renal failure requiring dialysis. History of renal failure requiring dialysis. Renal failure requiring hemo- or peritoneal dialysis Patients on dialysis Renal dysfunction: Creatinine levels > mg/dL or chronic dialysis. Subjects undergoing renal dialysis Renal failure requiring hemo- or peritoneal dialysis Renal failure requiring hemo-or peritoneal dialysis Not currently on renal dialysis or has a history of significant renal impairment Patients must not be dialysis dependent Patients on dialysis Patients on dialysis or with transplanted organs Renal failure requiring hemo-or peritoneal dialysis Diagnosis of kidney disease requiring dialysis Patients with renal dysfunction (GFR <) or patients on dialysis Currently on dialysis Chronic renal insufficiency requiring dialysis