Patients with a history of any one or more of the following thromboembolic events within the past  months prior to study enrollment are NOT eligible for participation: \r\n* Pulmonary embolism\r\n* Untreated deep venous thrombosis (DVT)\r\n** Subjects with recent DVT who have been therapeutically coagulated for at least  weeks ARE eligible
Cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months\r\n* Note: subjects with recent DVT who have been therapeutically coagulated for at least  weeks are eligible
History of a major thromboembolic event =<  months prior to randomization, including cerebrovascular accident, transient ischemic attack (TIA), myocardial infarction, symptomatic pulmonary embolism (PE) or untreated deep venous thrombosis (DVT), or coronary artery bypass graft surgery; NOTE: Subjects with recent DVT or asymptomatic PE who have been treated with therapeutic anticoagulating agents for at least  weeks are eligible
History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism, or untreated deep venous thrombosis (DVT) within the past  months
Any of the following conditions =<  months prior to registration:\r\n* Cerebrovascular accident (CVA) or transient ischemic attack (TIA)\r\n* Serious or unstable cardiac arrhythmia\r\n* Admission for unstable angina or myocardial infarction\r\n* Cardiac angioplasty or stenting\r\n* Coronary artery bypass graft surgery\r\n* Pulmonary embolism, untreated deep venous thrombosis (DVT) or DVT which has been treated with therapeutic anticoagulation =<  days\r\n* Arterial thrombosis\r\n* Symptomatic peripheral vascular disease
Cerebrovascular accident at any time in the past, transient ischemic attack, deep venous thrombosis or pulmonary embolism in the past  months
History of cerebrovascular accident including transient ischemic attack, pulmonary embolism (including asymptomatic or previously treated pulmonary embolism [PE]), or untreated deep venous thrombosis within the past  months; patients with recent deep vein thrombosis (DVT) who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible
History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months; note: subjects with recent DVT who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible
History of cerebrovascular accident including transient ischemic attack (TIA), myocardial infarction, pulmonary embolism or untreated deep venous thrombosis (DVT), coronary artery bypass graft surgery within  months prior to registration; Note: subjects with recent DVT who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible
Patients with a history of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or insufficiently treated deep venous thrombosis (DVT) within the past  months; Note: Participants with recent DVT who have been treated with therapeutic anti-coagulants for at least  weeks are eligible, with the exception of participants being treated with warfarin, which is prohibited on this study; other oral anti-coagulants may be allowed after discussion with overall principle investigator (PI), but short half-life low molecular weight heparins are strongly preferred
History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months; Note: patients with recent DVT who have been treated with therapeutic anticoagulation agents for at least  weeks are eligible as long as their INR is stable and within inclusion criteria above
History of cerebrovascular accident including transient ischemic attack, pulmonary embolism (PE) (including asymptomatic or previously treated PE), or untreated deep venous thrombosis within the past  months; patients with deep venous thrombosis (DVT) who are being treated with therapeutic anti-coagulating agents are eligible
History of stroke, deep venous thrombosis (DVT), or transient ischemic attack (TIA)
Previous history of cerebrovascular accident (CVA), transient ischemic attack (TIA), angina pectoris, acute myocardial infarction (MI) or history of recent re-perfusion procedures (e.g. percutaneous transluminal coronary angioplasty [PTCA]), pulmonary embolus or untreated deep vein thrombosis (DVT) within  months from day  of study drug; NOTE: subjects with recent DVT who have been therapeutically anti-coagulated for at least  weeks are eligible
History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months.
History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months; Note: subjects with recent DVT who have been treated with therapeutic anticoagulating agents for at least  weeks prior to study treatment are eligible
History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months
Patient must not have a history of cerebrovascular accident including transient ischemic attack within the past  months; patients with recent deep venous thrombosis or pulmonary embolism who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible as long as INR is stable
History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within  months of registration; note: subjects with recent DVT who have been treated with therapeutic anti-coagulating agents for at least  weeks prior to registration and are fully anti-coagulated are eligible
History of cerebrovascular accident (CVA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months; Note: subjects with recent DVT who have been treated with therapeutic anti-coagulant agents for at least  weeks are eligible
History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months; Note: subjects with recent DVT who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible
History of cerebrovascular accident including transient ischemic attack, untreated deep venous thrombosis (DVT) or pulmonary embolism within the past  months; patients with recent DVT who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible
History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months; note: subjects with recent DVT who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible but must be monitored regularly for changes in relevant coagulation parameters as clinically indicated as well as any clinical bleeding episodes
History of cerebrovascular accident, pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months; subjects with recent DVT who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible
EXPANSION COHORT ONLY: History of cerebrovascular accident, pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months; subjects with recent DVT who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible
History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism, or untreated deep venous thrombosis (DVT) within the past  months; subjects with recent DVT who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible
History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months.
History of cerebrovascular accident including transient ischemic attack, pulmonary embolism, or untreated deep venous thrombosis within the past  months.
History of cerebrovascular accident, pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months; subjects with recent DVT who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible
History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months; note: subjects with recent DVT who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible
Patient must not have history of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past  months\r\n* Note: subjects with recent DVT who have been treated with therapeutic anti-coagulating agents for at least  weeks are eligible