Has a serious illness or medical condition(s) Any significant acute or chronic medical illness Serious illness or medical condition. Intercurrent illness that will interfere with the radiation therapy such as immunosuppression due to medication or medical condition Unstable or severe uncontrolled medical condition (e.g. unstable cardiac function, unstable pulmonary condition, uncontrolled diabetes) or any important medical illness or abnormal laboratory finding that would, in the investigators judgment, increase the risk to the patient associated with his or her participation in the study A serious illness or medical condition Serious illness or medical condition that could affect the safety or tolerability of study treatments Patients with serious unstable medical illness Patients with serious unstable medical illness Has a serious illness or medical condition(s) that would affect safety or tolerability of the study treatments Other serious illness or medical condition(s) (see protocol) Unstable or severe uncontrolled medical condition (eg, unstable cardiac function, unstable pulmonary condition), or any important medical illness or abnormal laboratory finding that would, in the Investigator's judgment, increase the subject's risk while participating in this study Other serious illness or medical conditions Patients with serious unstable medical illness The participant has a serious illness or medical condition including: If the patient has co-morbid medical illness, life expectancy attributed to the comorbid illness must be greater than months Significant or acute medical illness Patients with a serious unstable medical illness or another active cancer Serious concurrent illness, altered medical status or any uncontrolled medical condition Other serious concurrent illness or medical condition. Unstable or severe uncontrolled medical condition (eg, unstable cardiac function, unstable pulmonary condition), or any important medical illness or abnormal laboratory finding that would, in the investigator's judgment, increase the subject's risk while participating in this study Certain serious illness or medical condition(s) For Part D, have a serious illness or medical condition(s), including but not limited to the following: Known serious illness or medical condition Patients with serious unstable medical illness Other serious concurrent illness or medical condition. Serious cardiac illness or medical conditions Any serious illness or medical condition that could affect participation on trial Patients with serious unstable medical illness Serious cardiac illness or medical condition including but not confined to: Concurrent serious medical illness that could potentially interfere with protocol compliance (such medical illness will not include hepatitis or cirrhosis, as the degree of liver impairment caused by these diseases are covered by other exclusion criteria). Other serious concurrent illness or medical condition. Patients with a serious unstable medical illness or another active cancer Significant acute or chronic medical illness. Acute major illness (e.g., unstable cardiovascular condition, etc.) Acute major illness (e.g., unstable cardiovascular condition, etc.) Acute major illness (e.g., infection, unstable cardiovascular condition, etc.) Acute major illness (e.g. unstable cardiovascular condition, etc.) Has a serious illness or medical condition(s)