Major surgical procedure within weeks prior to planned initiation of study therapy Major surgery =< weeks before first dose of study drug or incomplete recovery from a prior major surgical procedure Major surgical procedure within days prior to the study. Major surgical procedure within weeks prior to Day Prior major surgical procedure or radiation therapy within weeks of the randomization Participants who underwent minor surgical procedure within days prior to initiating therapy Prior radiation therapy or chemotherapy within weeks or major surgical procedure within weeks of the first dose of study treatment Patients who have had radiotherapy or minor surgical procedure within days, or major surgical procedure within days prior to administration of first dose of study drug are not eligible; patients with inadequate recovery from prior surgical procedure are also not eligible Must not have undergone a major surgical procedure < weeks prior to registration Planned surgical procedure within the next days Major surgical procedure within weeks prior study treatment initiation Surgical procedure w/in wks of starting study drug. Or pt has surgery-related complications to Grade ? Inadequate recovery from any prior surgical procedure, or having undergone any major surgical procedure within weeks prior to C/D. Any planned pleurodesis as part of the surgical procedure. Major surgical procedure other than for diagnosis within weeks prior to initiation of study treatment\r\n* Placement of a stent or central venous access catheter (e.g., port or similar) is not considered a major surgical procedure and is therefore permitted Inadequate recovery from any prior surgical procedure, or having undergone any major surgical procedure within weeks prior to C/D. Major surgical procedure (as defined by the Investigator) within days prior to the start of study treatment Any major surgical procedure within weeks of first study treatment Invasive surgical procedure within days prior to study pre-registration Major surgical procedure within weeks of first study treatment Any of the following therapies prior to registration:\r\n* Chemotherapy =< days\r\n* Immunotherapy =< days\r\n* Biologic therapy =< days\r\n* Hormonal therapy =< days\r\n* Monoclonal antibodies =< days\r\n* Radiation therapy =< days\r\n* Minor surgical or interventional procedure =< days\r\n Major surgical procedure =< days Major surgical procedure (e.g. laparotomy, bowel resection) weeks prior to start of the study drug Must have fully healed from any surgical procedure to be safe for lumbar puncture according to treating neurosurgeon and at least days should have elapsed since the surgical procedure Major surgical procedure within four weeks prior to administration of the first dose of ARQ a. To be eligible for the study treatment, all surgical wounds must be fully healed and any surgery-related adverse events must recover to Grade ? . Patients who have had any major surgical procedure within days of day Major surgical procedure within days prior to enrollment Major surgical procedure within days of study enrollment, or anticipated while on study Major surgical procedure within four weeks prior to administration of the first dose of study drug To be eligible for study treatment, all surgical wounds must be fully healed and any surgery-related adverse events (AE) must recover to Grade ? Patients who have had any major surgical procedure within days of Day . BM biopsy is not considered a major surgical procedure. For the purposes of this study, the procedure with the highest estimated risk of DSC (as predicted by the Surgical Risk Calculator) will be denoted at the time of first registration as the index procedure that will be performed during the index surgery Status post \r\n* Elective (curative or palliative) major cancer surgery at the time of the index surgery (patient may have undergone more than one of these procedures) OR \r\n* Elective surgical procedure(s) listed as an option (i.e., CPT code) in the Surgical Risk Calculator webpage (patient may have undergone more than one of these procedures)\r\n** For the purposes of this study, the procedure that was performed with the highest estimated risk of DSC (as predicted by the Surgical Risk Calculator) will be denoted at the time of second registration as the index procedure performed during the index surgery Status post elective surgical procedure(s) not listed as options in the Surgical Risk Calculator webpage Patients with a major surgical procedure or other investigational agents within days before study enrollment Patients must have evaluable disease; patients must begin treatment within days of their surgical procedure Patients who have had any major surgical procedure within days of Day . Patients less than weeks post major surgical procedure (all surgical wounds must be fully healed). For the purpose of this criterion, a major surgical procedure is defined as one requiring the administration of general anesthesia Patients must have recovered from any surgical procedure before enrolling on this study Subject has had a major surgical procedure and has not completely recovered within days prior to the start of study treatment. Inadequate recovery from any prior surgical procedure, or having undergone any major surgical procedure within weeks prior to C/D. Patients who have had a surgical procedure unrelated to the study within days or major surgery within month prior to the administration of the study drug Major surgical procedure within weeks prior to randomization. Patient must have recovered from all surgery-related complications. Embolization procedure or ablation procedure to treat tumor within weeks of first dose of STA- Non-study related minor surgical procedure =< days, or major surgical procedure =< days, prior to the first dose of rucaparib; in all cases, patients must be sufficiently recovered and stable before treatment administration Patients who have had any major surgical procedure within days of day Major surgical procedure less than weeks from start of protocol treatment Major surgical procedure within weeks of treatment Major surgical procedure within weeks prior to enrolment. Major surgical procedure other than for diagnosis within days prior to first dosing or during the course of the study. Subject is going through another surgical procedure (other than ileostomy or adhesiolysis) during the surgery. Major surgical procedure within weeks prior to Study Day Inadequate recovery from any prior surgical procedure or major surgical procedure within weeks prior to administration of first dose of study drug. Anticipate having a major surgical procedure during the course of the study. Major surgical procedure (as defined by the investigator) within days prior to Study Day or incomplete recovery from any prior surgery. Patients who have had any major surgical procedure within days prior to day Major surgical procedure within weeks prior to starting treatment; patients must have recovered from any effects of any major surgery and surgical wound should have healed prior to starting treatment Has undergone chemotherapy within weeks of the anastomosis procedure and/or radiation within days of the anastomosis procedure Subject is undergoing a neurologic surgical procedure; Subject is undergoing a spinal surgical procedure; Subject is undergoing an emergency surgical procedure; Major surgical procedure other than for diagnosis within days prior to DC Major surgical procedure within days prior to the first dose of IP. Major surgical procedure within days prior to the first dose of Investigational Product; Major surgical procedure other than for diagnosis within weeks prior to randomization Surgical axillary staging procedure prior to study procedure (with exception of FNA or core biopsy). Major surgical procedure within days prior to the first dose of Investigational Product Planned/or anticipated major surgical procedure during the course of the study Planned surgical procedure that can impact the conduct of the study Radiotherapy or minor surgical procedure within weeks, or major surgical procedure within weeks prior to administration of first dose of study drug; inadequate recovery from prior surgical procedure Major surgical procedure within weeks Major surgical procedure within weeks ( days) prior to enrollment (port placement is not considered a major surgical procedure) Any major surgical procedure or radiation within weeks of first study treatment Patients less than weeks post major surgical procedure (all surgical wounds must be fully healed); for the purpose of this criterion, a major surgical procedure is defined as one requiring the administration of general anesthesia Major surgical procedure within days of day of therapy Major surgical procedure (including periodontal) within weeks Subject has had a major surgical procedure (other than a biopsy) within days prior to the first dose of study drug, or one is planned during the course of the study. Major surgical procedure (other than study related biopsy), or a major surgical procedure is planned to occur during the planned study duration Subject has had a major surgical procedure (other than study-related biopsy) within days prior to the first dose of study drug, or a major surgical procedure is planned to occur during the study. Patients who have had any major surgical procedure within days of day Radiation therapy or major surgical procedure within weeks of the first dose. Major surgical procedure within weeks prior to Day A major surgical procedure within weeks prior to the planned first day of study drug dosing or a surgical procedure is planned during the course of the study. Major surgery ? weeks before first dose of study drug, or incomplete recovery from a prior major surgical procedure Major surgical procedure within weeks prior to initiation of study treatment Surgical procedure or clinically significant trauma within weeks of first dose of study treatment Major surgical procedure within days prior to Day or incomplete recovery from any prior surgery History of major surgical procedure within days prior to start of study treatment Patient who has undergone recent major surgery, other than diagnostic surgical procedure within weeks prior to randomization Any major surgical procedure within weeks prior to the first dose of study drug; Surgical resection or major surgical procedure within weeks prior to the start of SL-, or stereotactic biopsy within days prior to the start of SL-. Prior chemotherapy or a major surgical procedure within weeks, or radiotherapy within weeks prior to first study treatment Major surgical procedure within weeks prior to Day Patients with inadequate recovery from any prior surgical procedure, or patients having undergone any major surgical procedure within weeks prior to first study drug administration. Patients with inadequate recovery from any prior surgical procedure, or patients having undergone any major surgical procedure within month prior to first study drug administration. Occurrence of major intraoperative complications that require resuscitation or deviation from the planned surgical procedure. Patients who have had a major surgical procedure within the past weeks Major surgical procedure within days Major surgical procedure within weeks prior to study treatment Major surgical procedure within days prior to study enrollment Major surgical procedure within weeks prior to Day Patients must be less than months from the surgical procedure for this recurrence Major surgical procedure(s) within previous weeks prior to study enrollment Major surgical procedure within weeks of treatment Patients who have had any major surgical procedure within days of day A major surgical procedure (other than study related biopsy), or a major surgical is planned to occur during the study Surgical procedure where both arms are required to be tucked at the patient's side Major surgical procedure within days of first study treatment Demonstrates characteristics that are unrealistic/unreasonable with the risks involved with the surgical procedure >= days elapsed from the last surgical procedure (including biopsy, surgical resection, wound revision, or any other major surgery involving entry into a body cavity) Patient is within months of a major surgical procedure Undergone abdominal-perineal resection, Hartmann procedure, or other surgical procedure leaving the patient without a functioning rectum Patients must be scheduled for a procedure capable of providing a definitive pathological diagnosis and evaluating for complications of the esophageal sponge on the same day as the study procedure, either:\r\n* Upper endoscopy\r\n* Surgical esophagectomy current surgical procedure is a revision surgery for implant failure or infection; Planned surgical procedure Definitive breast surgical procedure prior to enrollment. Major surgical procedure within weeks of first study treatment Major invasive surgical procedure occurring between the first treatment-eligible PET/CT examination and end of radiotherapy that would affect the treatment target region Patients must be scheduled for a procedure capable of providing a definitive pathologic diagnosis and evaluating for complications of the esophageal sponge on the same day as the study procedure, either upper endoscopy or surgical esophagectomy Patient must have recovered from any surgical procedure before enrolling on this study Patient must not require a major surgical procedure =< days prior to beginning therapy Patient must not require an intermediate surgical procedure =< days prior to beginning therapy Prior major surgical procedure or radiation therapy within specified period of the first dose of study treatment (with defined exception). Prior major surgical procedure or radiation treatment within weeks of initiation of study treatment (not including limited radiation used for palliation of bone pain)