Patients must be able to swallow capsules Patients must be able to swallow whole capsules Patients must be able to swallow intact capsules Patients must be able to swallow intact capsules Able to swallow capsules Inability to swallow capsules or known gastrointestinal malabsorption Able to swallow ribociclib capsules Patient must be able to swallow capsules Able to swallow capsules Able to swallow capsules The subject is unable to swallow capsules. Inability to swallow capsules Inability to swallow gelatin capsules, or any medical condition that interferes with normal gastrointestinal absorption Inability to swallow capsules, since capsules cannot be crushed or broken Patients must be able to swallow capsules Patient must be able to swallow capsules Are able to swallow capsules Unable to swallow capsules or disease significantly affecting gastrointestinal function Patients must be able to swallow intact capsules Patients must be able to swallow capsules Are able to swallow capsules. Able to swallow intact capsules Inability to swallow capsules, since capsules cannot be crushed or broken The subject is unable to swallow capsules Ability to swallow capsules unless enrolled in Part E Part E: Any patient unable to swallow capsules who otherwise meet all other eligibility criteria for Part A (expansion) B, C or D Able to swallow capsules Patients must be able to swallow AZD capsules Ability to swallow and retain capsules. Ability to swallow capsules Inability to swallow capsules, since capsules cannot be crushed or broken PART GROUP INCLUSION CRITERIA: Subjects taking capsule formulations must be able to swallow capsules PART GROUP A INCLUSION CRITERIA: Subjects taking capsule formulations must be able to swallow capsules PART GROUP INCLUSION CRITERIA: Subjects taking capsule formulations must be able to swallow capsules Impaired gastrointestinal (GI) function or GI disease that may alter absorption of ceritinib or inability to swallow up to five ceritinib capsules daily; although, patients unable to swallow capsules will be allowed to participate in this study, by following the specific instructions on making a slurry of the medication Patients must be able to swallow intact capsules whole Patient must be able to swallow capsules Unable to swallow capsules Patients with malabsorption syndrome or other condition that would interfere with intestinal absorption; patients must be able to swallow capsules Patient must be able to swallow capsules Able to swallow capsules, with no surgical or anatomic condition that will preclude the patient from swallowing and absorbing oral medications Participants must be able to swallow capsules Able to swallow capsules whole (pomalidomide capsules cannot be crushed, dissolved or broken) Patients must be able to swallow whole capsules Patients must be able to swallow capsules Patient must be able to swallow capsules Patients must be able to swallow capsules Must be able to swallow ribociclib capsules Patients must be able to swallow capsules whole PHASE II: Patients must be able to swallow capsules whole Known inability to swallow capsules Patients must be able to swallow whole capsules Patients must be able to swallow capsules whole Part C: Patients must be able to swallow intact capsules Patients unable to swallow whole capsules Able to swallow whole capsules Patients must be able to take oral medications; patients must be able to swallow capsules whole without crushing or altering them in any way are able to swallow capsules Patients must be able to swallow whole capsules Inability to swallow capsules. Unable to swallow capsules or disease significantly affecting gastrointestinal function Patients must be able to swallow whole capsules Subject is able to swallow capsules Unable to swallow capsules or disease significantly affecting gastrointestinal function Are able to swallow capsules Unable to swallow capsules Patients must be able to swallow capsules Inability to swallow capsules Patients must be able to swallow whole capsules Inability to swallow capsules. Able to swallow capsules Patients who cannot swallow capsules Patients must be able to swallow intact capsules Inability to swallow capsules or known gastrointestinal malabsorption Ability to swallow oral capsules Are able to swallow capsules Inability to swallow the HKI- capsules Able to swallow capsules Able to swallow capsules Inability to swallow capsules Patients must be able to swallow whole capsules; capsules must not be crushed or chewed; capsules must not be opened Known inability to swallow up to five ceritinib (LDK) capsules daily Inability to swallow oral capsules Able to swallow capsules and maintain adequate hydration Patients will be excluded if they are unable to swallow capsules whole. Must be able to swallow whole capsules Patients must be able to swallow capsules Patients must be able to swallow whole capsules Inability to swallow capsules, since capsules cannot be crushed or broken Able to swallow whole capsules Patients must be able to swallow capsules Patients must be able to swallow either intact capsules or mini-tabs without chewing Patient must have the ability to swallow multiple capsules Able to swallow capsules Able to swallow oral capsules without difficulty. Able to swallow capsules Patient must be able to swallow capsules (phase III only) Patients must be able to swallow whole capsules Unable to swallow capsules or disease significantly affecting gastrointestinal function