No history of the following:\r\n* Active known or suspected autoimmune disease\r\n* Patients with human immunodeficiency virus (HIV) are eligible if the lymphocytes >  cluster of differentiation (CD)+ cells and no detectable viral load\r\n* Symptomatic, untreated, or uncontrolled brain metastases present\r\n* Active autoimmune colitis \r\n* Autoimmune panhypopituitarism \r\n* Autoimmune adrenal insufficiency \r\n* Known active hepatitis B or C\r\n** Hepatitis B can be defined as:\r\n*** Hepatitis B surface antigen (HBsAg) >  months\r\n*** Serum hepatitis B virus (HBV) deoxyribonucleic acid (DNA) , IU/ml ( copies/ml), lower values ,-, IU/ml (- copies/ml) are often seen in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B\r\n*** Persistent or intermittent elevation in alanine aminotransferase (ALT)/alanine aminotransferase (AST) levels\r\n*** Liver biopsy showing chronic hepatitis with moderate or severe necroinflammation\r\n** Hepatitis C can be defined as:\r\n*** Hepatitis C antibody (Ab) positive\r\n*** Presence of hepatitis C virus (HCV) ribonucleic acid (RNA)\r\n* Known active pulmonary disease with hypoxia defined as:\r\n** Oxygen saturation < % on room air or\r\n** Oxygen saturation < % despite supplemental oxygen
No known active hepatitis B or C\r\n* Active hepatitis B can be defined as: \r\n** Hepatitis B virus surface antigen (HBsAg) detectable for >  months;\r\n** Serum hepatitis B virus (HBV) DNA , IU/ml ( copies/ml); lower values ,-, IU/ml (- copies/ml) are often seen in hepatitis B virus e antigen (HBeAg)-negative chronic hepatitis B\r\n** Persistent or intermittent elevation in ALT/AST levels \r\n** Liver biopsy showing chronic hepatitis with moderate or severe necroinflammation\r\n* Active hepatitis C can be defined as: \r\n** Hepatitis C antibody (AB) positive AND \r\n** Presence of hepatitis C virus (HCV) RNA
No history of the following:\r\n* Child Pugh class B or C liver disease\r\n* Chronic active hepatitis defined as: \r\n** Hepatitis B surface antigen (HBsAg) >  months\r\n** Serum hepatitis B virus (HBV) deoxyribonucleic acid (DNA) , IU/ml ( copies/ml), lower values ,-, IU/ml (- copies/ml) are often seen in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B\r\n** Persistent or intermittent elevation in alanine aminotransferase (ALT)/aspartate aminotransferase (AST) levels\r\n** Liver biopsy showing chronic hepatitis with moderate or severe necroin?ammation
Active hepatitis B, either active carrier (hepatitis B surface antigen positive [HBsAg +]) or viremic (hepatitis B virus [HBV] deoxyribonucleic acid [DNA] >= , copies/mL, or >= , IU/mL)
Active hepatitis B, either active carrier (hepatitis B surface antigen [HBsAg] +) or viremic (hepatitis B virus [HBV] deoxyribonucleic acid [DNA] >= , copies/mL, or >= , IU/mL)
Active hepatitis B, either active carrier (hepatitis B surface antigen positive [HBsAg +]) or viremic (hepatitis B virus [HBV] deoxyribonucleic acid [DNA] >=, copies/mL, or >= , IU/mL)
Active hepatitis B, either active carrier (hepatitis B surface antigen positive [HBsAg +]) or viremic (hepatitis B virus [HBV] deoxyribonucleic acid [DNA] >= , copies/mL, or >= , IU/mL)
Active hepatitis B, either active carrier (hepatitis B virus surface antigen [HBsAg] +) or viremic (hepatitis B virus [HBV] deoxyribonucleic acid [DNA] >= , copies/mL, or >= , IU/mL)
Patients with active hepatitis B, either active carrier (hepatitis B surface antigen [HBsAg] +) or viremic (hepatitis b virus [HBV] deoxyribonucleic acid [DNA] >= , copies/mL, or >= , IU/mL)
Active hepatitis B, either active carrier (hepatitis B surface antigen [HBsAg] +) or viremic (hepatitis B virus [HBV] deoxyribonucleic acid [DNA] >= , copies/mL, or >= , IU/mL)
Active hepatitis B, either active carrier (hepatitis B surface antigen [HBsAg] +) or viremic (hepatitis B virus [HBV] deoxyribonucleic acid [DNA] >/= , copies/mL, or >= , IU/mL).
Has uncontrolled human immunodeficiency virus (HIV) (defined as HIV RNA > copies/ml and CD+ count</mm on antiretroviral therapy)infection, or hepatitis B (defined as ALT >  x ULN, and HBV DNA > IU/ml), or hepatitis C (defined as ALT >  x ULN, persistent viremia on antiviral therapy) infections.
Patients with active hepatitis B, either active carrier (hepatitis B virus surface antigen [HBsAg] +) or viremic (hepatitis B virus [HBV] deoxyribonucleic acid [DNA] >= , copies/mL, or >= , IU/mL)
Hepatitis B virus deoxyribonucleic acid (DNA) levels >, international units/mL.
No history of the following: \r\n* Active known or suspected autoimmune disease\r\n* Human immunodeficiency virus (HIV) with CD+ count <  or detectable viral load; patients with HIV, undetectable viral load, and CD+ count >=  are eligible\r\n* Known active hepatitis B or C\r\n** Hepatitis B can be defined as: \r\n*** Hepatitis B virus surface antigen (HBsAg) >  months\r\n*** Serum hepatitis B virus (HBV) deoxyribonucleic acid (DNA) , IU/ml ( copies/ml), lower values ,-, IU/ml (- copies/ml) are often seen in hepatitis B virus e antigen (HBeAg)-negative chronic hepatitis B\r\n*** Persistent or intermittent elevation in alanine aminotransferase (ALT)/aspartate aminotransferase (AST) levels\r\n*** Liver biopsy showing chronic hepatitis with moderate or severe necroin?ammation\r\n** Hepatitis C can be defined as:\r\n*** Hepatitis C antibody (AB) positive\r\n*** Presence of hepatitis C virus (HCV) RNA\r\n* Known active pulmonary disease with hypoxia defined as oxygen saturation < % on room air
Active hepatitis B, either active carrier (hepatitis B surface antigen [HBsAg] +) or viremic (hepatitis B virus [HBV] DNA >= , copies/mL, or >= , IU/mL)