Patients must NOT be receiving valproic acid, an histone deacetylase (HDAC) inhibitor, and may not have previously received any HDAC inhibitor prior to enrollment (e.g. valproic acid, entinostat, vorinostat) unless discussed with the study chair; patients must not have received prior HDAC therapy for the treatment of their malignancy
Previous therapy with histone deacetylase (HDAC) inhibitor.
Patients who have received any other histone deacetylase (HDAC) inhibitors or immunomodulatory (IMID) agents for any reason are not eligible
Patients with prior treatment of histone deacetylase (HDAC) inhibitors or doxorubicin liposome or doxil are eligible
Previous therapy with histone deacetylase (HDAC) inhibitor
Prior treatment with histone deacetylase (HDAC) inhibitors (e.g. valproic acid, Zolinza (SAHA), romidepsin (Istodax)
Patients who have received histone deacetylase (HDAC) inhibitors (including valproic acid, entinostat, vorinostat) are excluded
Patients who have received prior histone deacetylase (HDAC) inhibitors, or brentuximab vedotin, may be permitted to enter the study unless they have received an HDAC inhibitor or brentuximab within the last  months
HDAC inhibitors:  weeks
Patients with a prior history of treatment with histone deacetylase (HDAC) inhibitors (e.g., SNDX-/entinostat, LAQ-, LBH, PXD-/belinostat, etc); patients who have received valproic acid will be excluded from this study
Concomitant use of other histone deacetylase (HDAC) inhibitors
Patients taking concomitant histone deacetylase (HDAC) inhibitors; use of HDAC inhibitor like compounds such as valproic acid for epilepsy is permitted if there is at least a  week wash out
Prior treatment with vorinostat or other HDAC inhibitor
Use of any drug with histone deacetylase (HDAC) inhibiting activity.
Prior treatment for MDS with the histone deacetylase (HDAC) inhibitors Zolinza (vorinostat), Belenodaq (belinostat), Farydak (panobinostat), Istodax (romidepsin/depsipetide), or investigational agent with significant action as an HDAC inhibitor.
Any previous treatment with a HDAC inhibitor, including citarinostat
Patient had prior treatment with an histone deacetylase (HDAC) inhibitor (e.g., romidepsin [Depsipeptide], NSC-, MS , LAQ-, belinostat [PXD-], LBH, MGCD, CRA, etc); patients who have received compounds with HDAC inhibitor-like activity, such as valproic acid, as anti-tumor therapy should not enroll in this study; patients who have received such compounds for other indications, e.g. valproic acid for epilepsy, may enroll after a -day washout period
Prior therapy with histone deacetylase (HDAC) inhibitor.
Patients must not have previously received a histone deacetylase (HDAC) inhibitor in a clinical trial setting (entinostat, romidepsin, belinostat, panobinostat, vorinostat)
Patient has received previous treatment with histone deacetylase (HDAC) inhibitors
Prior therapy with an anti-cytotoxic T-lymphocyte antigen  (CTLA) antibody or an histone deacetylases (HDAC) inhibitor
Prior therapy with a histone deacetylase (HDAC) inhibitor
Prior therapy with HDAC inhibitor
Participants who have a history of prior MM treatment with panobinostat, or an alternative histone deacetylase (HDAC)-inhibitor
No prior treatment with any HSP or histone deacetylase (HDAC) inhibitor compound is allowed
Prior anti-neoplastic treatment with any HSP or histone deacetylase (HDAC) inhibitor compound
Patients receiving histone deacetylase (HDAC) inhibitors or compounds with HDAC inhibitor like activity, such as valproic acid, are ineligible; patients who have received such agents may enroll on this study after a -day washout period
Prior treatment with a histone deacetylase (HDAC) inhibitor
Received prior HDAC inhibitor therapy
Patients who have had prior treatment with a histone deacetylase (HDAC) inhibitor (e.g., romidepsin [Depsipeptide], NSC-, MS , LAQ-, belinostat [PXD-], LBH, MGCD, CRA, etc); patients who have received compounds with HDAC inhibitor-like activity, such as valproic acid, as anti-tumor therapy should not enroll in this study; patients who have received such compounds for other indications, e.g. valproic acid for epilepsy, may enroll after a -day washout period
Patient had prior treatment with an histone deacetylases (HDAC) inhibitor (e.g., romidepsin [Depsipeptide], NSC-, MS , LAQ-, belinostat [PXD-], LBH, MGCD, CRA, etc); patients who have received compounds with HDAC inhibitor-like activity, such as valproic acid, as anti-tumor therapy should not enroll in this study; patients who have received such compounds for other indications, e.g. valproic acid for epilepsy, may enroll after a -day washout period
Chemotherapy, radiotherapy, HDAC inhibitors, or other plasma cell directed therapy within  weeks
Concurrent use of other histone deacetylase inhibitors (e.g. valproic acid) are prohibited except for histone deacetylase (HDAC) inhibitors or HDAC-inhibitor like agents used for non-cancer treatment (e.g. epilepsy), where a  day washout is allowed
Prior therapy with HDAC inhibitors (except for CTCL)
Prior use of valproic acid or any other histone deacetylase (HDAC) inhibitor for lymphoma treatment
Prior treatment with an HDAC inhibitor.
Prior therapy with other histone deacetylase (HDAC) inhibitors, including valproic acid
Prior therapy with histone deacetylase (HDAC) inhibitors or immunomodulatory drugs (IMDs) (lenalidomide or thalidomide)