Performance status , or WHO performance status of or Performance Status of , , or Performance status of or Performance status of or Performance status -. Disease status: Disease status Adequate Performance Status Performance status =< Patient has a WHO performance status - Performance status of - Performance status of , , or Good performance status Performance status of to Performance status =< Performance status =< Performance status of or Performance status of - Performance status of , , or WHO Performance Status , or . A maximum of / of patients in cohorts A & B may be WHO performance status Must have adequate performance status: Performance status of , , or Known HER status Patients with HER(-) status Performance status =< Performance status - Performance status >= % Performance status >= Performance status will not be considered Performance status =< WHO performance status - HER status negative Performance status - Performance status of or Performance Status: Performance status - Kamofsky performance status ?% Patient has an ECOG performance status ? (Patients with lower performance status based solely on bone pain secondary to multiple myeloma will be eligible) Performance Status -; Performance Status - Performance status must be -. Patients with any performance status are eligible for enrollment WHO performance status of or Performance status or ECOG performance status =< , unless the decline of the performance status is considered to be related to CLL symptoms WHO performance status - Performance status >= % Performance status - WHO performance status of ? Pre-study ECOG performance status -. Patients with lower performance status based solely on bone pain will be eligible. Performance status of , , or Adequate performance status. Adequate performance status, defined as: Performance status: Performance Status of or Performance Status of or . WHO performance status of - Performance Status of or WHO performance status of ? . Performance Status of or WHO performance status -. Performance status - Acceptable level of performance status (both) Performance status of or better Performance status of - Patients must have a performance status of - Performance status =< Performance status or performance status of or Performance status as per protocol