Cardiovascular Risks as outlined in the protocol. Understand study design, risks, and benefits and have signed informed consent Failure of research participant to understand the basic elements of the protocol and/or the risks/benefits of participating in this phase I study; a legal guardian may substitute for the research participant Subject must understand risks and benefits of the protocol and be able to give informed consent Failure of research participant or legally responsible parent or guardian to understand the basic elements of the protocol and/or the risks/benefits of participating in this phase I study. Unable to understand the purpose and risks of the study Failure of research participant to understand the basic elements of the protocol and/or the risks/benefits of participating in this phase I study; a legal guardian may substitute for the research participant Understand the study purpose, requirements, and risks Failure of research participant to understand the basic elements of the protocol and/or the risks/benefits of participating in this phase I study Failure of research participant to understand the basic elements of the protocol and/or the risks/benefits of participating in this phase I study Patients should be in such a health condition in the opinion of the attending physician that with the administration of mifepristone benefits may outweigh risks Subjects must be able to understand the potential risks and benefits of the study, and be able to read and give written informed consent Failure of research participant to understand the basic elements of the protocol and/or the risks/benefits of participating in this phase I study; a legal guardian may substitute for the research participant Understands the potential risks and benefits of study participation and is willing to provide written informed consent. Known thrombophilic risk factors. Exception: Subjects for whom the potential benefits of participating in the study outweigh the potential risks of thromboembolic events, as determined by the investigator Ability to understand the purpose and risks of the study. Subjects must be able to understand the potential risks and benefits of the study and must be able to read and provide written, informed consent for the study Subjects must be able to understand the potential risks and benefits of the study and must be able to read and provide written, informed consent for the study Failure of research participant to understand the basic elements of the protocol and/or the risks/benefits of participating in this pilot study; a legal guardian may substitute for the research participant Understands study design, risks, and benefits and have signed informed consent Patients with known thrombophilic risk factors; exception: patients for whom the potential benefits of participating in the study outweigh the potential risks of thromboembolic events, as determined by the investigator Able to comprehend the full nature and purpose of the study, including possible risks and side effects. Inability to understand the risks and benefits of the study Patient Volunteers: Inability to understand the risks and benefits of the study Patient Volunteers/Contrast Enhancement Sub-group: Inability to understand the risks and benefits of the study PHASE I: Women that answer or more of the questions about the benefits and risks of the study incorrectly will be excluded