Use of other investigational drugs at the time of screening or within the last days. Subjects may not receive any other concomitant investigational agents Concomitant use of any anticancer therapy or use of any investigational agent(s). Concomitant use of other cytotoxic or cytostatic drugs other than PTX Concomitant use of other investigational agents. Use of any investigational drugs within days prior to dosing Serious uncontrolled concomitant disease that would contraindicate the use of the investigational drug used in this study or that would put the subject at high risk for treatment-related complications. Concomitant use of other investigational agents Use of other investigational drugs Concomitant use of any other investigational drugs Concomitant use of any other investigational or anticancer agent(s). Concomitant use of other investigational agents Prior use of investigational drugs =< days prior to registration Concomitant use of any other investigational drugs Concomitant use of any other investigational drugs Subjects may not receive any other concomitant investigational agents Subjects receiving concomitant treatment with radiotherapy or other investigational drugs Concomitant use of any other investigational drugs Use of other investigational drugs Serious uncontrolled concomitant disease that would contraindicate the use of any of the investigational drugs used in this study or would put the participants at high risk for treatment-related complications Use of anti-cancer treatment (including investigational drugs) within days Use of investigational drugs within weeks of signing consent or foreseen use during the study Not receiving any other investigational agents (i.e., unlabeled drugs or drugs under an investigational new drug [IND] for initial efficacy investigations) Not receiving any other investigational agents (i.e., unlabeled drugs or drugs under an investigational new drug (IND) for initial efficacy investigations Concomitant investigational therapy Concomitant investigational therapy