Proteinuria with urinary protein is =< + on dipstick or routine urinalysis, or a -hour urine collection for protein < mg of protein in hours, within days prior to administration of study treatment Baseline urinalysis should show urine protein < + and must be obtained within days prior to registration; if urine protein is + or greater, then urine protein by hour collection must show less than grams of protein Urine protein: =< mg/dl in urinalysis or =< + on dipstick, unless quantitative protein is < mg in a hour (h) urine sample Urinary protein is > + on dipstick and the required following -hour urine collection shows urinary protein > mg; Urinary protein =< + on dipstick or routine urinalysis (if urine dipstick or routine urinalysis is +, a -hour urine collection for protein must demonstrate < mg of protein in hours) Urine protein via dipstick =< + or =< mg/dl Urinary protein =< + on dipstick or routine urinary analysis (UA); if dipstick or routine UA is >= +, a -hour urine collection for protein must demonstrate < mg of protein in hours Urine protein: =< mg/dl in urinalysis or =< + on dipstick, unless quantitative protein is < mg in a hour (h) urine sample Additional inclusion criteria for patients on the arm pembrolizumab plus ramucirumab:\r\n* Urinary protein is < mg/dL on routine urinalysis. If urine routine urinalysis indicates proteinuria >= mg/dL, then a -hour urine collection must be performed and must demonstrate urine protein < g to allow the patient to participate in the study. Urine protein =< mg/dL in urinalysis or =< + on dipstick, unless quantitative protein is < mg in a hour urine sample Urine protein by dipstick <+ or UPC =< . by urinalysis Urinary protein < + by urine dipstick (if dipstick is >= + then a -hour urine collection can be done and the patient may enter only if urinary protein is < g per hours) The patients urinary protein is =< + on dipstick or routine urinalysis (urine analysis [UA]; if urine dipstick or routine analysis is >= +, a -hour urine collection for protein must demonstrate < mg of protein in hours to allow participation in this protocol) The patients urinary protein is =< positive (+) (=< - mg/dl) on dipstick or routine urinalysis (urinary analysis [UA]; if urine dipstick or routine analysis is >= + (>=- mg/dl), a -hour urine collection for protein must demonstrate < mg of protein in hours to allow participation in this protocol) Urine protein < + on dipstick test or routine urinalysis; if the proteinuria on these tests is >= +, then a -hour urine test must be collected and must demonstrate < g protein in hours to allow participation Urinary protein < + by urine dipstick (if >= +, a -hour urine protein must show protein < g per hours) Proteinuria: if urine dipstick shows + protein, hour urinary protein should be done and be less than =< grams/ hours Urine protein should be screened by urinalysis; if protein is + or higher, hour urine protein should be obtained and the level should be < mg for patient enrollment Urine protein must be screened by urine analysis within days prior to registration; patient must not have greater than + proteinuria on two consecutive dipsticks taken no less than days apart; however, if the first urinalysis shows no protein, then a repeat urinalysis is not required Urine protein/creatinine (UPC) ratio < . or urine protein =< + on dipstick or routine urinalysis (UA); if UPC >= . or urine dipstick or routine analysis is >= +, a -hour urine collection for protein must demonstrate < , mg of protein in hours to allow participation in the study Patients whose urinary protein is =< + on a dipstick or routine urinalysis (UA); if routine analysis is > +, a -hour urine collection for protein must demonstrate < mg of protein in hours to allow participation in this protocol) Have urinary protein ?+ on dipstick or routine urinalysis. Urinalysis dipstick for urinary protein performed within days prior to randomization must be -+ protein. If urine dipstick result is greater than or equal to + protein, a -hour urine protein must be less than . g/ hours. Participant's urinary protein is ? + on dipstick or routine urinalysis (UA); if urine protein ? +, a -hour urine collection must demonstrate < milligrams (mg) of protein in hours to allow participation in the study Urine protein must be screened by urinalysis; if protein is + or higher, -hour urine protein should be obtained and the level should be < mg for patient enrollment Known proteinuria defined by >= + protein by urinalysis (UA) or >= gram protein by hour urine collection; Note: Subjects that are >= + or greater on dipstick but < g protein on hour urine ARE eligible to participate Urinary protein is <+ on dipstick or routine urinalysis. Urinary protein =< + by urine analysis; if urine protein is > + then a -hour urine collection can be done and the patient may enter only if urinary protein is < g per hours Urine protein =< + on dipstick or routine urinalysis; if urine dipstick or routine urinalysis indicates proteinuria >= +, then a -hour urine must be collected and must demonstrate < mg of protein in hours Urinary protein =< mg/dL in urinalysis or =< + on dipstick, unless quantitative protein is < mg in a h urine sample Urinary protein < + (unless total quantitative protein is < mg protein/day as determined by hour [H] urine collection) Quantitative urine protein by dipstick =< Urinary protein < + by urine dipstick; if dipstick is >= + then a -hour urine collection can be done and the patient may enter only if urinary protein is < g per hours Spot urine must not show + or more protein in urine or the patient will require a repeat urinalysis; if repeat urinalysis shows + protein or more, a -hour urine collection will be required and must show total protein excretion < mg/ hours Spot urine must not show + or more protein in urine or the subject will require a repeat urinalysis. If repeat urinalysis shows + protein or more, a -hour urine collection will be required and must show total protein excretion <, mg per hours. Continued from Inclusion #: Serum creatinine /= mL/min (CrCl = Wt (kg) x (-age)/ x Cr level, female x .) for pts w/ creatinine levels above institutional normal; Amylase & lipase < . x the ULN; Urinalysis (UA) must show less than + protein in urine, or the pt will require a repeat UA. If repeat UA shows + protein or more, a hour urine collection will be required & must show total protein