Concurrent use of another investigational drug or device therapy (i.e., outside of study treatment) during, or within  weeks prior to study registration
Concurrent use of another investigational drug or device therapy (i.e., outside of study treatment) during, or within  weeks of trial entry (signing of the informed consent form)
Concurrent use of another investigational drug or device therapy (i.e., outside of study treatment) during, or within  weeks of trial entry (signing of the informed consent form)
Investigational drug therapy outside of this trial during or within  weeks prior to CD.
Investigational drug therapy outside of this trial during or within  weeks of first study treatment
Excluded therapies and medications, previous and concomitant\r\n* Concurrent anti-cancer therapy (chemotherapy, radiation therapy, surgery, immunotherapy, biologic therapy, or tumor embolization) other than study treatment (regorafenib)\r\n* Prior use of regorafenib\r\n* Concurrent use of chemotherapy, radiotherapy or another investigational drug or device therapy (i.e., outside of study treatment) during, or within  weeks of trial entry (signing of the informed consent form)\r\n* Major surgical procedure, open biopsy, or significant traumatic injury within  days before start of study medication\r\n* Use of any herbal remedy (e.g. St. Johns wort [Hypericum perforatum])
Concurrent use of another investigational drug or device therapy (i.e., outside of study treatment) during, or within  days prior to registration
Concurrent use of another investigational drug or device therapy (ie, outside of study treatment) during, or within  weeks of trial entry (signing of the informed consent form).
Concurrent use of another investigational drug or device (i.e., outside of study treatment) during, or within  weeks of trial entry (signing of the informed consent form)
Excluded therapies and medications, previous and concomitant:\r\n* Concurrent anti-cancer therapy (chemotherapy, surgery, immunotherapy, biologic therapy, anti-HER targeting therapies, or tumor embolization) other than Ra  dichloride; concurrent external beam radiation therapy is permitted\r\n* Prior use of Ra- dichloride\r\n* Concurrent use of another investigational drug or device therapy (i.e., outside of study treatment) during, or within  weeks of trial entry (signing of the informed consent form)
Concurrent use of another investigational drug or device therapy (i.e., outside of study treatment) during, or within  days of trial entry (signing of the informed consent form)
Concurrent use of another investigational drug or device therapy (i.e., outside of study treatment) during, or within  weeks of trial entry (signing of the informed consent form)
Concurrent use of another investigational drug or device therapy (i.e., outside of study treatment) during, or within  weeks of trial entry (signing of the informed consent form)
Concurrent use of another investigational drug or device therapy (i.e., outside of study treatment) during, or within  weeks of trial entry (signing of the informed consent form)
Concurrent use of another investigational drug or device during, or within  weeks of starting study treatment
Concurrent use of another investigational drug or device during, or within  weeks of starting study treatment
Concurrent use of another investigational drug or device therapy (i.e., outside of study treatment) during, or within  weeks of trial entry (signing of the informed consent form)