Known intolerance or hypersensitivity to everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus) Previous hypersensitivity to rapamycin or rapamycin derivatives History of allergic reactions, intolerance or hypersensitivity attributed to compounds of similar chemical or biologic composition to TRC and/or everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus) Known intolerance or hypersensitivity to rapamycin analogs (e.g. sirolimus, temsirolimus) Known intolerance or hypersensitivity to everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus) Known intolerance or hypersensitivity to everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus) TREATMENT: Patients who have received prior everolimus or other mechanistic target of rapamycin (mTOR) inhibitors or those with known intolerance or hypersensitivity to other rapamycin analogs (e.g., sirolimus, temsirolimus) would not be eligible to receive everolimus on study; if these patients have mutations of interest in pathways other than the phosphatidylinositol-,-bisphosphate -kinase, catalytic subunit alpha (pIK) pathway, they will be eligible to receive agents based on that mutation Known intolerance or hypersensitivity to Everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus) Known intolerance or hypersensitivity to everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus) Known intolerance or hypersensitivity to everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus) Known intolerance or hypersensitivity to vitamin E, everolimus or to rapamycin derivatives Known intolerance or hypersensitivity to everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus) Known intolerance or hypersensitivity to everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus) Known intolerance or hypersensitivity to everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus) Previously received rapamycin or rapamycin analogs, including ridaforolimus, temsirolimus, or everolimus Known intolerance to lenvatinib, everolimus (or other rapamycin derivatives), or any of the excipients Known intolerance or hypersensitivity to everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus) Known intolerance or hypersensitivity to everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus);