The subject has received another investigational agent within days of the first dose of study drug The subject has received any other type of investigational agent within days before the first dose of study treatment The participant has received any other type of investigational agent within days before the first dose of study treatment The subject has received any other type of investigational agent within days before the first dose of study treatment The participant has received another investigational agent within days of the first dose of study drug Received any investigational agent within the days before the start of study treatment (st dose of fludarabine) The subject has received any other type of investigational agent within days before the first dose of study treatment Received another investigational agent (defined as any agent/device that has not received regulatory approval for any indication) within days of the first dose of study drug for a nonmyelosuppressive agent, or days of the first dose of study drug for a myelosuppressive agent Received any investigational agent within the days before the start of study treatment (st dose of fludarabine phosphate [fludarabine]) Received any investigational agent within the days before the start of study treatment (st dose of fludarabine) mCRPC EXPANSION COHORT: The patient has received any other type of investigational agent within days before the first dose of study treatment The subject has received any other type of investigational agent within days before the first dose of study treatment At least days after the last dose of a biologic agent. Receipt of any other type of investigational agent within days before the first dose of study treatment The subject has received any other type of investigational agent within days before the first dose of study treatment Any other type of investigational agent within weeks before the first dose of study treatment RENAL COHORT: The subject has received any other type of investigational agent within days before the first dose of study treatment The subject has received any other type of investigational agent within days before the first dose of study treatment Any other type of investigational agent within days before the first dose of study treatment Any anti-cancer treatment within days or any investigational agent within days before the first dose of study drug. Investigational agent received within days prior to the first dose of study drug The subject has received any other type of investigational agent within days before the first dose of study treatment The subject has received any other type of investigational agent within days before the first dose of study treatment Having received an investigational agent within days prior to the first dose of study treatment The subject has received any other type of investigational agent within days before the first dose of study treatment The participant has received any other type of investigational agent within days before the first dose of study treatment Treatment with any investigational agent within days before the first dose of study treatment Having received an investigational agent with days of receiving the first dose of study drug on this trial Use of any other type of investigational agent or treatment concurrently or within days before the first dose of study treatment The subject has received any other type of investigational agent within days before the first dose of study treatment The subject has received any other type of investigational agent within days before the first dose of study treatment The subject has received any investigational agent within days before the first dose of study treatment Received any investigational agent within the days before the start of study treatment (st dose of ALT-)