Any active disease condition which would render the protocol treatment dangerous or impair the ability of the patient to receive protocol therapy. Active uncontrolled infection, underlying medical condition, or other serious illness that would impair the ability of the patient to receive protocol treatment Active infection or serious underlying medical condition that would impair the ability of the patient to received protocol therapy Any active disease condition which would render the protocol treatment dangerous or impair the ability of the patient to receive protocol therapy. Active infection or serious underlying medical condition that would impair the ability of the patient to received protocol therapy Patients who are immunosuppressed (including known HIV infection), have a serious active infection at the time of treatment, have known hepatitis C, or have any serious underlying medical condition that would impair the ability of the patient to receive protocol treatment. Patient has an active uncontrolled infection, including a urinary tract infection, underlying medical condition, or other serious illness that would impair the ability of the patient to receive study treatment or undergo study procedures Has an active uncontrolled infection, including a urinary tract infection, underlying medical condition, or other serious illness that would impair the ability of the subject to receive protocol treatment. Serious active infection at the time of enrolment, or another serious underlying medical condition that would impair the ability of the patient to receive study treatment Subjects must not have a history of other serious underlying medical or psychiatric condition that, in the opinion of the investigator, would impair the ability to receive, tolerate and or comply with the planned treatment and follow-up Serious underlying medical conditions that, per the Investigator's discretion, could impair the ability of the patient to participate in the trial Active infection or other serious underlying medical condition which would impair the ability of the patient to receive the planned treatment Any serious underlying medical condition that, in the opinion of the enrolling physician, would impair the ability of the patient to receive protocol treatment Active infection or any serious underlying medical condition, which would impair the ability of the patient to receive protocol treatment. Presence of a comorbid disease or medical condition that would impair the ability of the patient to receive or comply with the study protocol Patients with any serious underlying medical condition that would impair their ability to receive or tolerate the planned treatment. Serious active infection at the time of study entry, or another serious underlying medical condition that would impair the ability of the patient to receive study treatment Comorbid disease or a medical or psychiatric condition that would impair the ability of the patient to receive or comply with the study protocol. Serious active infection at the time of study entry, or another serious underlying medical condition that would impair the ability of the patient to receive study treatment. Patients who have post-obstructive pneumonia or other serious infection at the time of registration or other serious underlying medical condition that would impair the ability of the patient to receive protocol treatment Subjects must not have post-obstructive pneumonia or other serious infection at the time of registration or other serious underlying medical condition that would impair the ability of the subjects to receive protocol treatment Active infection or serious underlying medical condition that would impair the patient's ability to receive protocol treatment Any severe underlying medical conditions including presence of laboratory abnormalities, which could impair the ability to participate in the study or the interpretation of its results. Active infection or any serious underlying medical condition, which would impair the ability of the patient to receive protocol treatment Serious active infection, or serious underlying medical condition. Patient has an active uncontrolled infection, including a urinary tract infection, underlying medical condition, or other serious illness that would impair the ability of the patient to receive protocol treatment. Active infection or serious underlying medical condition that would impair the patient's ability to receive protocol treatment Serious active infection at the time of treatment, or another serious underlying medical condition that would impair the ability of the patient to receive protocol treatment. Serious underlying medical condition which would impair the ability of the patient to receive protocol treatment, in the opinion of the treating physician Active infection or serious underlying medical condition that would impair the patient's ability to receive protocol treatment Patients with any serious underlying medical condition that would impair their ability to receive or tolerate the planned treatment No active serious infection or other comorbid illness which would impair ability to participate in the trial Any serious underlying medical or psychiatric condition (e.g., alcohol or drug abuse), dementia or altered mental status or any issue that would impair the ability of the patient to receive or tolerate the planned treatment, to understand informed consent or that in the opinion of the investigator would contraindicate the patient's participation in the study or that would confound the results of the study. Serious underlying medical condition which would impair the ability of the patient to receive protocol treatment, in the opinion of the treating physician Any serious, active underlying medical condition that would impair the ability of the subjects to receive study treatment Any serious underlying medical condition that, in the opinion of the investigator or medical monitor, would impair the ability to receive or tolerate the planned treatment Active uncontrolled infection, underlying medical condition including unstable cardiac disease, or other serious illness impairing the ability of the patient to receive protocol treatment. Any active disease condition which would render the protocol treatment dangerous or impair the ability of the patient to receive protocol therapy. Serious active infection at the time of randomization, or other serious underlying medical conditions that would impair the ability of the participant to receive protocol treatment Any serious underlying medical condition that, in the opinion of the investigator or medical monitor, would impair their ability to receive or tolerate the planned treatment Serious active infection at time of randomization or other serious underlying medical conditions that would impair the ability of the participant to receive protocol treatment A serious underlying medical condition that would impair the ability of the patient to receive protocol treatment Patients must not have serious infection or other serious underlying medical condition which would impair the ability of the patient to receive protocol treatment; these need not be specified in the history and physical and can be documented through signature on the eligibility checklist; severe, active co-morbidity, defined as follows: Underlying medical condition including unstable cardiac disease, or other serious illness that would impair the ability of the patient to undergo treatment Any medical condition that may interfere with ability to receive protocol treatment Serious underlying medical condition that would impair the ability of the patient to receive protocol treatment, specifically cardiac diseases, uncontrolled hypertension or renal diseases No serious medical or psychiatric illnesses that would prevent informed consent; patients with post-obstructive pneumonia are eligible; patients with an active serious infection or other serious underlying medical condition that would otherwise impair their ability to receive protocol treatment are ineligible Any medical condition that may interfere with ability to receive protocol treatment Patient has an active uncontrolled infection, underlying medical condition, or other serious illness that would impair the ability of the patient to receive protocol treatment Serious underlying medical condition that would impair patient's ability to tolerate the imaging procedure A serious underlying medical condition that would otherwise impair the patients ability to receive treatment and imaging studies Presence of a comorbid disease or medical condition that would impair the ability of the patient to receive or comply with the study protocol