Life-threatening illness unrelated to cancer Subjects with uncontrolled serious infections or a life-threatening illness (unrelated to tumor) Have other life-threatening illness Presence of other life-threatening illness Known diagnosis of human immunodeficiency virus, active chronic hepatitis B, or C, life-threatening illness unrelated to cancer, or any serious medical or psychiatric illness that could, in the investigator's opinion, potentially interfere with participation in this study Known human immunodeficiency virus (HIV) infection, active chronic hepatitis B or C not contained with anti-viral therapy, life threatening illness unrelated to cancer, or any serious medical or psychiatric illness that could, in investigators opinion, potentially interfere with participation in this study Life-threatening illness unrelated to cancer Life-threatening illness unrelated to cancer Life-threatening illness unrelated to cancer Known human immunodeficiency virus (HIV) infection, active chronic hepatitis B or C not contained with anti-viral therapy, life threatening illness unrelated to cancer, or any serious medical or psychiatric illness that could, in investigators opinion, potentially interfere with participation in this study Have other life-threatening illness Life-threatening illness unrelated to cancer Life-threatening illness unrelated to cancer or any serious medical or psychiatric illness that could, in the Investigator's opinion, potentially interfere with participation in this study. Patient must not be known to have human immunodeficiency virus (HIV) infection, active chronic hepatitis B or C, life-threatening illness unrelated to cancer, or any serious medical or psychiatric illness that could, in the investigators opinion, potentially interfere with participation in this study; patients will be tested for hepatitis B or C or HIV infection during screening if they are considered by the investigator to be at higher risk for these infections and have not been previously tested Life threatening illness unrelated to cancer. Clinically significant infections as judged by the treating investigator. Subjects must not have been diagnosed with human immunodeficiency virus (HIV) infection, active chronic hepatitis B or C, life-threatening illness unrelated to cancer, or any serious medical or psychiatric illness that could, in the investigator's opinion, potentially interfere with participation in this study. Subjects should be tested for hepatitis B or C or HIV infection during screening only if they are considered by the investigator to be at high risk for these infections. Life-threatening illness unrelated to cancer Life-threatening illness unrelated to cancer. Life-threatening illness unrelated to cancer Life-threatening illness unrelated to cancer Known active chronic hepatitis B or C, life-threatening illness unrelated to cancer, or any serious medical or psychiatric illness that could, in the investigator's opinion, potentially interfere with participation in this study Life-threatening illness unrelated to cancer that could, in the investigator's opinion, make the participant not appropriate for this study. Life-threatening illness or serious (acute or chronic) medical or psychiatric illness unrelated to cancer. Has life-threatening illness unrelated to cancer.