Subject is unable or unwilling to participate a study related procedure Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures Subject is unable or unwilling to participate in a study related procedure Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures Is unable or unwilling to participate in a study related procedure Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures. Unable or unwilling to complete the follow-up evaluations required for the study Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in the study Unwilling or unable to participate in the study Unwilling or unable to participate in the study Unwilling or unable to participate in the study Unwilling or unable to participate in the study Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in all required study evaluations and procedures The patient is unwell or unable to participate in all required study evaluations and procedures Patients who, in the judgment of the investigator, may be unable to participate in the required study procedures EXCLUSION CRITERIA (PRIOR TO IBRUTINIB ADMINISTRATION): Unwilling or unable to participate in all required study evaluations and procedures Unwilling or unable to participate in the study