Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patients risk or limit the patients adherence with study requirements Any other medical or psychological condition that would preclude participation in the study or compromise ability to give informed consent Acute or chronic medical or psychological illnesses that prevent endoscopy procedures Chronic or acute renal or hepatic disorder or any other condition, medical or psychological that, in the opinion of the investigator, could jeopardize the subjects safe participation Physical or psychological condition which would impair study participation; or Any other medical, psychological, or social condition that may interfere with study participation or compliance, or compromise patient safety in the opinion of the investigator Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patients risk or limit the patients adherence with study requirements Any medical, psychological or social condition that in the opinion of the investigator, would preclude participation in this study. Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patients risk or limit the patients adherence with study requirements Any other medical, psychological, or social condition that may interfere with study participation or compliance, or compromise patient safety in the opinion of the investigator Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patients risk or limit the patients adherence with study requirements Any other co-existing medical or psychological condition(s) that will preclude participation in the study or compromise ability to give informed consent and/or comply with study procedures. Any medical or psychological condition that, in the opinion of the investigator, might interfere with the subjects participation in the trial, poses any additional risk for the subject, or confounds the assessment of the subject Patients with a medical or psychological impediment to probable compliance with the protocol should be excluded Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patients risk or limit the patients adherence with study requirements Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patients risk or limit the patients adherence with study requirements Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patients risk or limit the patients adherence with study requirements DONOR: No psychological traits or psychological or medical conditions which make them unlikely to tolerate the procedure Any other medical, psychological, or social condition that may interfere with study participation or compliance, or compromise patient safety in the opinion of the investigator Patients with any serious/poorly controlled medical or psychological conditions that would be exacerbated by treatment, would complicate protocol compliance Patients with a medical or psychological impediment to probable compliance with the protocol should be excluded DONOR: Serious medical or psychological illness Psychological or social reasons that would hinder or prevent compliance with the requirements of the protocol or compromise the informed consent process. Psychological or social reasons that would hinder or prevent compliance with the requirements of the protocol or compromise the informed consent process. Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patients risk or limit the patients adherence with study requirements Any medical or psychological condition that in the opinion of the principal investigator would interfere with safe completion of the trial Any other medical, psychological, or social condition that may interfere with study participation or compliance, or compromise patient safety in the opinion of the investigator or medical monitor Must not have concomitant medical, psychological or social circumstances which would interfere with compliance with the protocol treatment and follow-up Patients with concurrent medical, psychological or social conditions of such severity that the investigator deems it unwise to enter the patient on protocol Unrelated Donor: Serious medical or psychological illness DONOR: Serious medical or psychological illness Any other medical, psychological, or social condition that may interfere with study participation or compliance, or compromise patient safety in the opinion of the investigator Medical, social, or psychological factors that would prevent the patient from receiving or cooperating with the full course of therapy Any other medical, psychological, or social condition that may interfere with study participation or compliance, or compromise patient safety in the opinion of the investigator or medical monitor Social or psychological conditions that the investigator judges may compromise study compliance Medical or psychological impediment to probable compliance with the protocol DONOR: Donors must not have psychological traits or psychological or medical conditions which make them unlikely to tolerate the procedure Uncontrolled concurrent significant medical or psychological co-morbidity Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patients risk, interfere with the patients participation in the study, or hinder evaluation of study results Patients must not have active uncontrolled infections, other medical or psychological/social conditions that might increase the likelihood of patient adverse effects or poor outcomes Acute or chronic medical or psychological illnesses that prevent endoscopy procedures Medical, psychological or surgical condition which the investigator feels might compromise study participation Physical or psychological condition which would impair study participation; or Has medical, social, or psychological factors that, in the opinion of the Investigator, could impact safety or compliance with study procedures Subjects with a medical or psychological impediment to probable compliance with the protocol Any significant psychological, medical, or surgical condition thought to compromise the participant, the study, or prevent informed consent Medical, psychological or surgical condition which the investigator feels might compromise study participation No medical, psychological or surgical condition which the investigator feels might compromise study participation Patients with severe psychological or medical illness Any other medical, psychological, or social condition that may interfere with study participation or compliance, or compromise patient safety in the opinion of the investigator Unstable or severe uncontrolled medical, psychological, or social condition Serious or unstable medical or psychological conditions that, in the opinion of the investigator would compromise the subjects safety or successful participation in the study Serious or unstable medical or psychological conditions that, in the opinion of the investigator, would compromise the subjects safety or successful participation in the study Serious or unstable medical or psychological conditions that, in the opinion of the investigator would compromise the subjects safety or successful participation in the study Serious or unstable medical or psychological conditions that, in the opinion of the investigator, would compromise the subjects safety or successful participation in the study Serious or unstable medical or psychological conditions that, in the opinion of the investigator, would compromise the subjects safety or successful participation in the study Serious or unstable medical or psychological conditions that, in the opinion of the investigator would compromise the subjects safety or successful participation in the study Serious or unstable medical or psychological comorbidities that, in the opinion of the investigator, would compromise the subjects safety or successful participation in the study Medical or psychological conditions which, in the opinion of the investigator, might create undue risk to the subject or interfere with the subjects ability to comply with the protocol requirements Serious or unstable medical or psychological conditions that, in the opinion of the investigator, would compromise the subjects safety or successful participation in the study Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patients risk or limit the patients adherence with study requirements Any concurrent condition, including psychological and social situations, which, in the opinion of the investigator, would adversely impact the subject or the interpretation of the study data.