Patients with vitiligo, endocrine deficiencies including type I diabetes mellitus, thyroiditis managed with replacement hormones including physiologic corticosteroids are eligible Diabetes mellitus type For Part G: Have type diabetes mellitus or a history of gestational diabetes mellitus. Participants with a type diabetes mellitus are eligible if adequate control of blood glucose level is obtained with oral therapy as documented by Hemoglobin Ac <%. Patients with controlled Type diabetes mellitus on a stable dose of insulin regimen may be eligible for this study. Type or Type diabetes mellitus requiring insulin at study entry Patients with controlled type diabetes mellitus on a stable insulin regimen are eligible Participants with a history of autoimmune hypothyroidism on a stable dose of thyroid replacement hormone or participants with controlled Type diabetes mellitus on a stable insulin regimen may be eligible for this study with approval by the medical monitor Uncontrolled diabetes mellitus. Patients with Type II diabetes are eligible if they require only oral hypoglycemic agents and fasting blood glucose level is ?. Patients with Type I diabetes are eligible if their glycosylated hemoglobin (HbAlc) is ?. Uncontrolled (per investigator judgment) type I or type II diabetes mellitus. Patients with uncontrolled type diabetes mellitus. If on a stable insulin regimen may be eligible, after discussion with principal investigator. History of multiple sclerosis, type diabetes mellitus (DM) or Guillain-Barre syndrome Patients with controlled type diabetes mellitus on a stable insulin regimen are eligible Subjects with uncontrolled type I or II diabetes mellitus Type diabetes mellitus or type diabetes mellitus actively receiving treatment History of autoimmune disease except treated/stable hypothyroidism, Type diabetes mellitus, and protocol-specified dermatologic conditions Patient with an established diagnosis of diabetes mellitus type I or uncontrolled type II Patients with active autoimmune disease, with exceptions of vitiligo, type I diabetes mellitus, hypothyroidism and psoriasis. Diabetic patients (type I or II diabetes mellitus) must have baseline hemoglobin (Hb)Ac levels NOT higher than .% at study entry For the Diabetes Expansion Cohort - Subjects with known history of type diabetes\n mellitus that are well-controlled on a stable dose of oral anti-diabetic agents such\n as metformin and/or sulfonylureas for weeks prior to screening. For the Diabetes Expansion Cohort - Subjects who have type diabetes mellitus,\n maturity onset diabetes of the young, hyperglycemia due to reasons other than type \n diabetes mellitus. History of autoimmune disease except controlled/treated hypothyroidism, type diabetes mellitus, or certain skin disorders Patients with an established diagnosis of diabetes mellitus type I or not controlled type II Subjects with uncontrolled type I or type II diabetes mellitus (defined as HgbAc > ). Type or Type diabetes mellitus requiring anti-hyperglycemic medications history of Diabetes Mellitus, type or type , Patients with controlled Type diabetes mellitus on a stable insulin regimen may be eligible. Type I or II diabetes mellitus with HbAc > .% at Screening. Known history of autoimmune disease (with the exceptions of medically-controlled hypothyroidism and type I diabetes mellitus) Patients with type II diabetes mellitus that is well controlled by dietary measures alone and have a hemoglobin Ac (HgAc) < % are eligible to participate; patients found to have a fasting glucose >= mmol/L (>= mg/dL) or glycosylated hemoglobin > % ( mmol/mol) at screening should be assessed for appropriate management according to local policy; those in whom dietary measures alone provide good diabetic control will be eligible for inclusion; type I or II diabetes mellitus requiring either insulin or oral hypoglycemics for routine management will be excluded History of type I diabetes mellitus; if a patient has type II diabetes, they must have a hemoglobin (hemoglobin AC) =< %; patients with a screening fasting glucose > mg/dL will be excluded Previously diagnosed diabetes mellitus Type I. Subjects with Type II diabetes are allowed if entry criteria are fulfilled Patients with controlled Type diabetes mellitus on a stable insulin regimen may be eligible. Type I or II diabetes mellitus with HbAc > .% at screening (modified by amendment ) Patient with type diabetes mellitus or not adequately controlled type diabetes mellitus Subject has Type Diabetes Mellitus or Type Diabetes Mellitus and currently being treated with insulin or sulfonylureas. DONOR: History of type I or type II diabetes mellitus Subjects with type or type diabetes mellitus Diabetes mellitus, unless it is type II diabetes adequately controlled with anti-diabetic agents (Ac < ) Type or diabetes mellitus History of Type I or Type II diabetes mellitus requiring insulin History of Type or diabetes mellitus requiring regular medication (other than metformin or other oral hypoglycemic agents) or fasting glucose ? mg/dL at the prestudy visit. If a diabetic cohort is enrolled, only subjects with a medical history of controlled Type or diabetes mellitus will be enrolled in the cohort. Patients with a known history of type or type diabetes mellitus Diagnosis of diabetes mellitus type Type I diabetes mellitus History of autoimmune disease. Patients with a history of autoimmune-related hypothyroidism on a stable dose of thyroid replacement hormone and patients with controlled type diabetes mellitus on a stable insulin regimen may be eligible for this study.