[c09aa8]: / Formatted Data / formatted_drugbank_data.csv

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# CUI Drug Indication
1 0 ['237057'] Lepirudin the heparin-induced thrombocypenia
2 1 ['318341'] Cetuximab , in combination with irinotecan, is the egfr-expressing, metastatic colorectal carcinoma in patients who are refracry irinotecan-based chemotherapy. administered as a single agent is the egfr-expressing, metastatic colorectal carcinoma in patients who are inlerant irinotecan-based chemotherapy.
3 2 ['337623'] Dornase alfa as adjunct therapy in the cystic fibrosis.
4 3 ['214470'] Denileukin diftitox cutaneous t-cell lymphoma
5 4 ['214555'] Etanercept is the moderately severely active rheumaid arthritis in adults and chronic moderate severe plaque psoriasis in adults. it is also manage signs and sympms polyarticular idiopathic arthritis in those aged 4 17 after insufficient response one or more disease-modifying anti-rheumatic drugs. is also improve psoriatic arthritis and ankylosing spondylitis.
6 5 ['60819'] Bivalirudin heparin-induced thrombocypenia and the prevention thrombosis. is use in patients undergoing percutaneous coronary intervention (pci), in patients at moderate high risk acute coronary syndromes due unstable angina or non-st segment elevation in whom a pci is planned.
7 6 ['42375'] Leuprolide prostate cancer, endometriosis, uterine fibroids and premature puberty
8 7 ['120608'] Peginterferon alfa-2a is the hcv in combination with other antiviral drugs in patients over 5 years age with compensated liver disease [fda label]. may be as a monotherapy in patients with contraindications or significant inlerance other anti-viral therapies. is also as a monotherapy adult patients with hbeag positive and hbeag negative chronic hepatitis b infection who have compensated liver disease and evidence viral replication and liver inflammation [fda label].
9 8 ['8410'] Alteplase acute myocardial infarction, acute ischemic strok and lysis acute pulmonary emboli
10 9 ['56188'] Sermorelin the dwarfism, prevention hiv-induced weight loss
11 10 ['202912'] Interferon alfa-n1 venereal or genital warts ca by the human papiloma virus
12 11 ['283838'] Darbepoetin alfa the anemia (from renal transplants or certain hiv )
13 12 ['11055'] Urokinase can be the pulminary embolism, coronary artery thrombosis, iv catheter clearance, and venous and arterial blood clots.
14 13 ['50610'] Goserelin treat hormone-sensitive cancers the breast (in pre- and peri- menopausal women) and prostate, and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). in addition, is in assisted reproduction and in the precocious puberty.
15 14 ['76895'] Reteplase lysis acute pulmonary emboli, intracoronary emboli and myocardial infarction
16 15 ['105694', '105695'] Erythropoietin use in the sympmatic anaemia associated with chronic renal failure (crf) in adult and paediatric patients. also use in the anaemia and reduction transfusion requirements in adult patients receiving chemotherapy solid tumours, malignant lymphoma or multiple myeloma, and at risk transfusion as assessed by the patient's general status (e.g. cardiovascular status, pre-existing anaemia at the start chemotherapy). also increase the yield aulogous blood from patients in a predonation program. when administered subcutaneously, epoetin zeta is equivalent epoetin alfa in terms clinical effectiveness.
17 16 ['36118'] Salmon Calcitonin in the sympmatic paget's disease patients unresponsive alternate s or inlerant such s. in addition, it is in emergency situations when serum calcium levels must be decreased quickly until the underlying condition is identified. it can also be added existing therapeutic regimens hypercalcemia such as intravenous fluids and furosemide, oral phosphate or corticosteroids, or other agents. calcinin can be in patients with azotemia and cases where intravenous fluids would be contra due limited cardiac reserves. also the post-menopausal osteoporosis in women more than 5 years post-menopause.
18 17 ['612937'] Interferon alfa-n3 the intralesional refracry or recurring external condylomata acuminata.
19 18 ['338036'] Pegfilgrastim leukocyte production, in non-myeloid cancer, neutropenia and bone marrow transplant.
20 19 ['69634'] Sargramostim the cancer and bone marrow transplant
21 20 ['9627'] Secretin diagnosis pancreatic exocrine dysfunction and gastrinoma
22 21 ['253453'] Peginterferon alfa-2b is the hcv in combination with [db00811] and a ns3/4a protease inhibir genotype 1 or without a ns3/4a protease inhibir genotypes 2-6 [fda label]. may be as a monotherapy in patients with contraindications or significant inlerance other anti-viral therapies.
23 22 ['1156'] Asparaginase acute lympocytic leukemia and non-hodgkins lymphoma
24 23 ['4952', '10579'] Thyrotropin Alfa residueal or recurrent thyroid cancer
25 24 ['1300486'] Antihemophilic factor, human recombinant the hemophilia a, von willebrand disease and facr xiii deficiency.
26 25 ['72435'] Anakinra the adult rheumaid arthritis and neonatal-onset multisystem inflammary disease (nomid).
27 26 ['5011'] Gramicidin D skin lesions, surface wounds and eye infections.
28 27 ['42386', '1426680'] Immune Globulin Human ivig is in the immunodeficiencies, as well as auimmune and inflammary disorders. these indications includes idiopathic thrombocypenic purpura, kawasaki disease, hypogammaglobulinemia, b cell chronic lymphocytic leukemia, bone marrow transplant complications, guillain-barré syndrome, chronic inflammary demyelinating polyneuropathy (cidp), multiple sclerosis, rheumaid arthritis, myesthenia gravis, wiskott–aldrich syndrome and inflammary skin diseases.
29 28 ['40028'] Anistreplase lysis acute pulmonary emboli, intracoronary emboli and myocardial infarction
30 29 ['253182', '631657'] Insulin Human as an adjunct diet and exercise improve glycemic control in adults and children with type 1 and type 2 diabetes mellitus.
31 30 ['259280'] Tenecteplase myocardial infarction and lysis intracoronary emboli
32 31 ['5882'] Interferon gamma-1b is the chronic granulomaus disease and osteopetrosis.
33 32 ['5879'] Interferon Alfa-2a, Recombinant the chronic hepatitis c, hairy cell leukemia, aids-related kaposi's sarcoma, and chronic myelogenous leukemia. also the oral warts arising from hiv infection.
34 33 ['3251'] Desmopressin oral mulations may be manage primary nocturnal enuresis in adults and vasopressin sensitive diabetes insipidus, and control temporary polyuria and polydipsia following head trauma or surgery in the pituitary region. intranasal and parenteral mulations may be manage spontaneous or trauma-induced bleeds (e.g. hemarthrosis, intramuscular hemama, mucosal bleeding) in patients with hemophilia a or von willebrand's disease type i. may also be parenterally prevent or treat bleeding in patients with uremia.
35 34 ['4256', '253149', '314620'] Coagulation factor VIIa Recombinant Human hemorrhagic complications in hemophilia a and b
36 35 ['139994'] Oprelvekin reduced platelet levels due chemotherapy
37 36 ['196319'] Palifermin oral mucositis associated with chemotherapy and radiation therapy.
38 37 ['4832', '261716'] Glucagon recombinant severe hypoglycemia, also in gastrointestinal imaging
39 38 ['70223'] Aldesleukin adults with metastatic renal cell carcinoma.
40 39 ['860178'] Botulinum Toxin Type B the patients with cervical dysnia reduce the severity abnormal head position and neck pain associated with cervical dysnia.
41 40 ['302379'] Omalizumab asthma ca by allergies
42 41 ['388084'] Lutropin alfa infertility in women with hypothalamic or pituitary insufficiency (hypogonadotropic hypogonadism) and pround lh deficiency (lh <1.2 international units [iu]/l)
43 42 ['54214'] Lyme disease vaccine (recombinant OspA) prophylactic lyme disease
44 43 ['86009', '314684'] Insulin Lispro the type 1 or 2 diabetes mellitus. be in conjunction with an intermediate or long-acting insulin except when in a continuous insulin infusion pump.
45 44 ['274783'] Insulin Glargine the type 1 or 2 diabetes mellitus in patients over 17 years old who require a long-acting (basal) insulin the control hyperglycemia. may be in pediatric patients with type 1 diabetes mellitus who require a long-acting (basal) insulin glycemic control.
46 45 ['58939', '898492'] Collagenase clostridium histolyticum promote debridement necrotic tissue in the severe burns and dermal ulcers including decubitus ulcers.
47 46 ['283821'] Rasburicase hyperuricemia, reduces elevated plasma uric acid levels (from chemotherapy)
48 47 ['68147'] Cetrorelix the inhibition premature lh surges in women undergoing controlled ovarian stimulation
49 48 ['327361'] Adalimumab rheumaid arthritis, psoriatic arthritis, ankylosing spondylitis, and crohn's disease.
50 49 ['61148'] Somatotropin dwarfism, acromegaly and prevention hiv-induced weight loss
51 50 ['84959'] Imiglucerase the gaucher's disease (deficiency in glucocerebrosidase)
52 51 ['83929'] Abciximab is as an adjunct percutaneous coronary intervention the prevention cardiac ischemic complications in patients undergoing percutaneous coronary intervention and in patients with unstable angina not responding conventional medical therapy when percutaneous coronary intervention is planned within 24 hours. is intended use with aspirin and heparin and has been studied only in that setting.
53 52 ['352374'] Drotrecogin alfa reduction mortality in patients with severe sepsis.
54 53 ['1294580'] Gemtuzumab ozogamicin the patients with cd33 positive acute myeloid leukemia in first relapse who are 60 years age or older and who are not considered candidates other cyxic chemotherapy. the patients aged 2 years and older with cd33-positive aml who have experienced a relapse or who have not responded initial (refracry).
55 54 ['535', '991743'] Alpha-1-proteinase inhibitor chronic augmentation and maintenance therapy in individuals with alpha1-proteinase inhibir (a1-pi) deficiency and clinical evidence emphysema.
56 55 ['34132'] Pegaspargase acute lymphoblastic leukemia
57 56 ['75917'] Interferon beta-1a relapsing/remitting multiple sclerosis, also condyloma acuminatum
58 57 ['59768'] Pegademase bovine adenosine deaminase deficiency
59 58 ['828529', '1370439'] Human Serum Albumin severe blood loss, hypervolemia, and hypoproteinemia.
60 59 ['75635', '288688'] Eptifibatide myocardial infarction and acute coronary syndrome.
61 60 ['191831', '1790539', '1927283'] Infliximab * reducing signs and sympms and inducing and maintaining clinical remission in adult or pediatric (≥ 6 years age) patients with moderately severely active **crohn’s disease** who have had an inadequate response conventional therapy * reducing the number draining enterocutaneous and recvaginal fistulas and maintaining fistula closure in adult patients with fistulizing **crohn’s disease**. * reducing signs and sympms, inducing and maintaining clinical remission and mucosal healing, and eliminating corticosteroid use in adult or pediatric (≥ 6 years age) patients with moderately severely active **ulcerative colitis** who have had an inadequate response conventional therapy. * , in combination with methotrexate, reducing signs and sympms, inhibiting the progression structural damage, and improving physical function in patients with moderately severely active **rheumaid arthritis**. * reducing signs and sympms in patients with active **ankylosing spondylitis**. * reducing signs and sympms active arthritis, inhibiting the progression structural damage, and improving physical function in patients with **psoriatic arthritis**. * the adult patients with chronic severe (i.e., extensive and/or disabling) **plaque psoriasis** who are candidates systemic therapy and when other systemic therapies are medically less appropriate.
62 61 ['25357', '227518', '386938'] Follitropin in women having been diagnosed with primary ovarian failure, it is in combination with human chorionic gonadotropin (hcg) assist in ovulation and fertility. in men with hypogonadotrophic hypogonadism, it is induce spermagenesis. may also be cause the ovary produce several follicles, which can then be harvested use in gamete intrafallopian transfer (gift) or in vitro fertilization (ivf).
63 62 ['11149'] Vasopressin the enuresis, polyuria, diabetes insipidus, polydipsia and oesophageal varices with bleeding
64 63 ['72257', '72258'] Interferon beta-1b is a drug the relapsing/remitting multiple sclerosis. it has been shown slow the advance the disease as well as decrease the frequency attacks.
65 64 ['59744'] Interferon alfacon-1 the hairy cell leukemia, malignant melanoma, and aids-related kaposi's sarcoma
66 65 ['5464', '486164'] Hyaluronidase increase absorption and distribution other injected drugs and rehydration.
67 66 ['221109', '1309342'] Insulin Pork the type i and ii diabetes mellitus.
68 67 ['224905'] Trastuzumab early stage her2-positive breast cancer, or metastatic breast cancer that substantially overexpress her2.
69 68 ['121191'] Rituximab cd20-positive non-hodgkins lymphoma, chronic lymphocytic leukemia, and rheumaid arthritis.
70 69 ['196102'] Basiliximab prophylactic kidney transplant rejection
71 70 ['42405'] Muromonab organ transplant recipients, prevention organ rejection
72 71 ['1745257'] Digoxin Immune Fab (Ovine) digixin overdose or digitalis glycoside xicity.
73 72 ['262323'] Ibritumomab tiuxetan non-hodgkin's lymphoma
74 73 ['22299'] Daptomycin the complicated skin and skin structure infections ca by susceptible strains gram-positive microorganisms.
75 74 ['263010'] Tositumomab non-hodgkin's lymphoma (cd20 positive, follicular)
76 75 ['278739'] Pegvisomant is a growth hormone recepr antagonist the acromegaly.
77 76 ['1712', '860168', '860189', '1000104'] Botulinum Toxin Type A the cervical dysnia in adults decrease the severity abnormal head position and neck pain associated with cervical dysnia. also the severe primary axillary hyperhidrosis that is inadequately managed with pical agents and the strabismus and blepharospasm associated with dysnia, including benign essential blepharospasm or vii nerve disorders in patients 12 years age and above. also cosmetically temporarily improve the appearance moderate--severe frown lines between the eyebrows (glabellar lines) as well as the excessive underarm sweating.
78 77 ['7880', '235379'] Pancrelipase exocrine pancreatic insufficiency in cystic fibrosis (ultresa™), chronic pancreatitis (viokace™ in combination with a pron pump inhibir), and pancreatecmy (viokace™ in combination with a pron pump inhibir).
79 78 ['10106'] Streptokinase the acute evolving transmural myocardial infarction, pulmonary embolism, deep vein thrombosis, arterial thrombosis or emolism and occlusion arteriovenous cannulae
80 79 ['117055'] Alemtuzumab (campath) is a monoclonal antibody therapy b-cell chronic lymphocytic leukemia.
81 80 ['46049'] Alglucerase the gaucher's disease (deficiency in glucocerebrosidase)
82 81 ['136300'] Capromab pendetide diagnosis prostate cancer and intra-pelvic metastases.
83 82 ['392509'] Laronidase the mucopolysaccharidosis
84 83 ['3008'] Cyclosporine transplant (kidney, liver, and heart) rejection, rheumaid arthritis, severe psoriasis.
85 84 ['299635'] Alefacept as an immunosuppressive drug, can be moderate severe chronic plaque psoriasis
86 85 ['4319'] Felypressin use as an alternative adrenaline as a localising agent, provided that local ischaemia is not essential.
87 86 ['134404'] Urofollitropin female infertility
88 87 ['356988'] Efalizumab the adult patients with moderate severe chronic plaque psoriasis, who are candidates photherapy or systemic therapy.
89 88 ['283550'] Choriogonadotropin alfa the female infertility
90 89 ['107044', '225741'] Antithymocyte immunoglobulin (rabbit) prevention renal transplant rejection
91 90 ['68442', '1433764', '1605064'] Filgrastim is in patients with acute myeloid leukemia receiving induction or consolidation chemotherapy. it is also in cancer patients receiving bone marrow transplant. in general, neutrophil counts in order decrease the risk infection or duration neutropenia in the aementioned patient populations. infection and neutropenia are adverse events associated with chemotherapy. furthermore, is also patients with severe chronic neutropenia. it mobilizes hemapoietic progenir cells in the peripheral blood collection by leukapheresis allow a more rapid engraftment. tbo- has a narrower indication prile than neupogen - it is a leukocyte growth facr the reduction in the duration severe neutropenia in patients with non-myeloid malignancies.
92 91 ['1300488'] Coagulation Factor IX (Recombinant) hemophilia (christmas disease).
93 92 ['115238'] Becaplermin pical skin ulcers (from diabetes)
94 93 ['259351', '338817'] Agalsidase beta fabry's disease (alpha-galacsidase a deficiency)
95 94 ['7617'] Octreotide acromegaly and reduction side effects from cancer chemotherapy
96 95 ['5880'] Interferon Alfa-2b, Recombinant the hairy cell leukemia, malignant melanoma, and aids-related kaposi's sarcoma.
97 96 ['301739'] Abarelix palliative advanced prostate cancer.
98 97 ['7824'] Oxytocin labor induction, augmentation labor, postpartum abbreviation third stage labor, postpartum control uterine bleeding, termination pregnancy and the evaluation fetal respirary capability. oxycin cannot be elective induction labor, there must be a clear medical requirement.
99 98 ['354770'] Natalizumab multiple sclerosis.
100 99 ['139896'] Enfuvirtide is an antiretroviral drug in combination therapy the hiv-1/aids.