[c09aa8]: / clusters / unpackedclusters / clust_77.txt

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Shortening fraction >= 27% by echocardiogramXx_NEWLINE_xXPatients must have a cardiac ejection fraction of >= 40%, or within institutional normal limits; a nuclear medicine gated blood pool examination is preferred; a 2-D ECHO scan is acceptable if a calculated ejection fraction is obtained and follow-up measurement of the cardiac ejection fraction will also be performed by echocardiography; measurement of cardiac ejection fraction should be within two weeks prior to allogeneic transplantationXx_NEWLINE_xXShortening fraction of >= 27% by echocardiogram, or ejection fraction of >= 50% by radionuclide angiogramXx_NEWLINE_xXCardiac ejection fraction >= 50% as determined by screening echocardiogramXx_NEWLINE_xXShortening fraction of >= 27% by echocardiogram (ECHO) ORXx_NEWLINE_xXEjection fraction >= 50% by ECHO or gated radionuclide studyXx_NEWLINE_xXNormal baseline cardiac ejection fraction >= 50%Xx_NEWLINE_xXShortening fraction of >= 27% by echocardiogram, orXx_NEWLINE_xXEjection fraction of >= 50% by radionuclide angiogramXx_NEWLINE_xXPatient must have a normal cardiac ejection fraction by pretreatment multigated acquisition scan (MUGA) or echocardiogram within 4 weeks prior to registration (resting ejection fraction >= 40% or >= 5% increase with exercise), shortening fraction by echocardiogram >= 24%, or to within the normal range of values for the institutionXx_NEWLINE_xXShortening fraction of >= 27% by echocardiogram, orXx_NEWLINE_xXEjection fraction of >= 50% by radionuclide angiogramXx_NEWLINE_xXPatients must have ejection fraction >= 45% based on echocardiogram performed within 28 days prior to registrationXx_NEWLINE_xXPatients with a history of congestive heart failure (CHF) or are at risk because of underlying cardiovascular disease or exposure to cardiotoxic drugs must have adequate cardiac function as clinically indicated:* Corrected QT interval (QTC) =< 480 msec* Shortening fraction of >= 27% by echocardiogram or ejection fraction of >= 50% by gated radionuclide studyXx_NEWLINE_xXShortening fraction of >= 27% by echocardiogram, or ejection fraction of >= 50% by radionuclide angiogramXx_NEWLINE_xXShortening fraction of >= 27% by echocardiogram OR ejection fraction of >= 50% by radionuclide angiogramXx_NEWLINE_xXShortening fraction of >= 27% orXx_NEWLINE_xXEjection fraction of >= 50%Xx_NEWLINE_xXNormal ejection fraction (echocardiogram [ECHO]) >= 53% (if a range is given then the upper value of the range will be used) or cardiac MRIXx_NEWLINE_xXShortening fraction of >= 27% by echocardiogram, or ejection fraction of >= 50% by gated radionuclide studyXx_NEWLINE_xXShortening fraction of >= 27% by echocardiogram, orXx_NEWLINE_xXEjection fraction of >= 50% by radionuclide angiogram or echocardiogramXx_NEWLINE_xXShortening fraction of >= 27% by echocardiogram, orXx_NEWLINE_xXEjection fraction of >= 50% by radionuclide angiogram or echocardiogramXx_NEWLINE_xXRECURRENT/ PROGRESSIVE DIPG (STRATUM 1): Cardiac function: * Left ventricular ejection fraction >= 50 by gated radionuclide study OR shortening fraction of >= 27% by echocardiogram* Patient has no ventricular arrhythmias except for benign premature ventricular contractions* Patient has a corrected QT (QTc) interval =< 450 msXx_NEWLINE_xXNON-PROGRESSED DIPG (STRATUM 2): Left ventricular ejection fraction >= 50 by gated radionuclide study OR shortening fraction of >= 27% by echocardiogramXx_NEWLINE_xXEjection fraction of < 50% (by radionuclide angiogram or echocardiogram) or shortening fraction of < 25% (by echocardiogram)* Note: for instances where both are reported, and one is below the threshold, the site will have the option to re-measure it centrally at the core labXx_NEWLINE_xXShortening fraction of >= 27% by echocardiogram, or ejection fraction of >= 50% by gated radionuclide studyXx_NEWLINE_xXShortening fraction of >= 27% by echocardiogramXx_NEWLINE_xXEjection fraction of >= 50% by radionuclide angiogram or echocardiogramXx_NEWLINE_xXShortening fraction of >= 27% by echocardiogram, or ejection fraction of >= 50% by gated radionuclide study within 7 days prior to enrollmentXx_NEWLINE_xX