Participants who are receiving or have received any other investigational agents within 14 days of enrollment Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents during the proposed treatment cycle. Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants may not be receiving any other investigational agents Participants may not be receiving any other investigational study agents or treatment for their cancer Participants may not be receiving any other investigational agents Participants who are receiving any other investigational agents. Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents within 21 days of the first dose of study drug Participants who are receiving any other investigational agents Participants may not be receiving any other investigational agents Participants who are receiving any other investigational agents STRATUM A: Participants receiving any other investigational agents STRATUM B: Participants receiving any other investigational agents STRATUM C: Participants receiving any other investigational agents Participants may not be receiving any other investigational agents targeting histiocytosis Participants who are receiving any other investigational agents, or any other anti-cancer therapy during study treatment Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants may not be receiving any other investigational agents Participants may not be receiving any other investigational agents Participants may not be receiving any other investigational agents Participants may not have received any other investigational agents in the previous 3 months Participants who are receiving any other investigational agents Participants who are receiving any investigational agents are not eligible Participants receiving any other investigational agents Participants may not be receiving any other investigational agents Participants who are receiving any other investigational agents Participants may not be receiving any other investigational agents for treatment of their cancer Participants may not be receiving any other investigational agents Participants who are receiving any other investigational agents Participants receiving any other investigational agents Participants who are receiving any other investigational agents after ASCT Participants may not be receiving any other investigational agents nor have participated in an investigational trial within the past 4 weeks Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents within 14 days before the first dose of study drug Participants may not be receiving any other investigational agents Participants who are receiving any other investigational agents PHASE II: Participants may not be receiving any other investigational agents Participants may not be receiving any biologics or investigational agents within 3 weeks Participants receiving any other investigational agents Participants who are receiving any other investigational agents Participants may not be receiving any other investigational anticancer agents Participants may not be receiving any other investigational agents Participants may not be receiving any other investigational agents Participants who are receiving concurrent therapy with other investigational agents Participants may not be receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants receiving any other anti-cancer or investigational agents Participants may not be receiving other investigational agents. Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants who are receiving any other investigational agents Participants may not be receiving any other investigational agents within 30 days of enrollment or during this study Participants who are receiving any other investigational agents Research participants receiving any other investigational agents Participants who are receiving any other investigational agents; participants who are receiving standard of care induction therapy on a clinical trial may be eligible after discussion with the overall principal investigator Participants who are receiving any other investigational agents Participants receiving any other investigational agents Participants who are receiving any other investigational agents within 4 weeks prior to enrollment; investigational antiretroviral agents for HIV are acceptable Participants may not be receiving any other investigational agents for treatment of GVHD or underlying disease for at least 7 days Participants may not be receiving investigational agents Participants may not be receiving any other investigational agents Participants may not be receiving any other investigational agents Participants may not be receiving any other investigational agents Participants who are receiving any other investigational agents Participants receiving any other investigational agents Participants may not be receiving any other investigational agents Participants may not be receiving any other investigational agents within past 3 months Participants may not have received any other investigational agents in the previous 3 months Participants may not be receiving any other investigational agents Participants may not be receiving any other investigational agents during the study Participants may not be receiving any other investigational agents Participants may not be receiving any other investigational agents Participants who are receiving any other investigational agents Participants receiving other investigational agents Participants who are receiving any other investigational agents