Creatinine clearance > 50 mL/min (calculated according to institutional standards or using Cockcroft-Gault or Modification of Diet in Renal Disease [MDRD] formula) Estimated glomerular filtration rate (eGFR) >= 45 mL/min/1.73 m^2 as calculated using the modification of diet renal disease equation Acceptable renal function with serum creatinine ? 1.5 x ULN or a calculated creatinine clearance ? 50 mL/min using the Cockcroft-Gault or Modification of Diet in Renal Disease formulas. Acceptable renal function with serum creatinine ? 1.5 x ULN or a calculated creatinine clearance ? 60 mL/min using the Cockcroft-Gault or Modification of Diet in Renal Disease formulas. Calculated creatinine clearance by Modification of Diet in Renal Disease (MDRD) (CrCl) >= 60 ml/min/1.73 squared meter Acceptable renal function with serum creatinine ? 1.5 x ULN or a calculated creatinine clearance ? 60 mL/min using the Cockcroft-Gault or Modification of Diet in Renal Disease formulas. Creatinine: glomerular filtration rate (GFR) > 30 as calculated by modification of diet in renal disease (MDRD) equation Adult population (patients >= 18 years): Serum creatinine =< 1.0 mg/dL; if serum creatinine > 1.0 mg/dL, then the estimated glomerular filtration rate (GFR) must be > 60 mL/min/1.73 m^2 as calculated by the Modification of Diet in Renal Disease equation Serum creatinine =< 2 mg/dL or calculated creatinine clearance of >= 40 ml/min within 14 days of registration using Modification of Diet in Renal Disease (MDRD) formula Serum creatinine > 1.5 x the ULN or an estimated glomerular filtration rate (eGFR) calculated using the Modification of Diet in Renal Disease (MDRD) equation of < 45 mL/min/1.73 m^2 Creatinine =< 2.0 mg/dL; however, patients with a creatinine > 2.0 mg/dL but with a calculated creatinine clearance of > 30 ml/min, as measured by the Modification of Diet in Renal Disease (MDRD) equation, will be eligible Creatinine clearance (CrCl) >= 40 ml/min; CrCl will be calculated using the modification of diet in renal disease (MDRD) equation Normal serum creatinine, or a creatinine clearance >= 40 ml/min (either measured using a 24 hour urine, calculated using Cockroft-Gault, or estimated using the Modification of Diet in Renal Disease [MDRD] method from the National Kidney Disease Education Program [NKDEP] [the method reported by M D Anderson Cancer Center (MDACC) laboratories]) DONOR: Serum creatinine within normal limits or a minimum creatinine clearance (CrCl) value of >= 60 ml/min calculated using the Modification of Diet in Renal Disease (MDRD) study equation Estimated serum creatinine clearance >= 50 ml/min (Modification of Diet in Renal Disease [MDRD] method) and/or serum creatinine =< 1.8 mg/dL An estimated glomerular filtration rate (eGFR) calculated using the Modification of Diet in Renal Disease (MDRD) equation of at least 45 mL/min/1.73 m^2 Adequate renal function with creatinine (Cre) =< 1.5; if greater, then glomerular filtration rate (GFR) > 60 mL/min/1.73 m^2 as calculated by the Modification of Diet in Renal Disease equation Creatinine clearance >= 40 mL/min/m^2 by Cockroft-Gault or Modification of Diet in Renal Disease (MDRD) equation Creatinine =< 1.5 mg/dL; however, patients with a creatinine > 1.5 mg/dL but with a calculated creatinine clearance of > 60 ml/min, as measured by the Modification of Diet in Renal Disease (MDRD) equation, will be eligible Patients with a serum creatinine > 1 are eligible if they have a calculated glomerular filtration rate (GFR) of >= 60 ml/min (i.e. class I or class II chronic kidney disease ) using the Modification of Diet in Renal Disease (MDRD) formula\r\n* Note: Daily creatinine and MDRD formula are only for the 1st induction cycle Serum creatinine =< 1.2 mg/dL or serum creatinine > 1.2 mg/dL and an estimated glomerular filtration rate (GFR) > 60 mL/min/1.73 m^2 as calculated by the modification of diet in renal disease equation Serum creatinine ? 1.5 x ULN or an estimated glomerular filtration rate of > 50 mL/min as calculated by the Modification of Diet in Renal Disease equation. Screening laboratory assessments outside the following limits: Absolute neutrophil count (ANC) <1,000/?l (<1.0 x 109/L) Platelet count <100,000/?l (<100 x 109/L) Hemoglobin <9 g/dL Total bilirubin >1.5 x institutional upper limit of normal (ULN) (i n case of known Gilbert's syndrome, <2 x ULN is allowed) Creatinine Creatinine clearance <30 mL/min (as calculated by Cockcroft-Gault formula or Modification of Diet in Renal Disease [MDRD] formula) Creatinine clearance > 45 mL/min.1.73m^2 as estimated by modified Modification of Diet in Renal Disease (MDRD) equation Serum creatinine < 1.5 x institutional Upper Limit of Normal (ULN) or an estimated glomerular filtration rate (eGFR) of > 50 ml/min as calculated by the Modification of Diet in Renal Disease (MDRD) equation Calculated creatinine clearance (estimated glomerular filtration rate [eGFR]) < 60 ml/min; EGFR values can be determined by either Modification of Diet in Renal Disease (MDRD) or Cockcroft-Gault equation based on the investigator’s discretion Serum creatinine =< 2 mg/dL or calculated creatinine clearance of >= 40 ml/min within 14 days of registration using Modification of Diet in Renal Disease (MDRD) formula Serum creatinine ? 1.5 x institutional ULN or an estimated glomerular filtration rate (eGFR) of > 50 ml/min as calculated by the Modification of Diet in Renal Disease (MDRD) equation. Serum creatinine within normal range for age, or if serum creatinine outside normal range, then renal function (estimated glomerular filtration rate [GFR] by modification of diet in renal disease [MDRD] formula) > 40 mL/min/1.73 m^2 Serum creatinine < 1.5 mg/dL or creatinine clearance greater than or equal to 40 cc/min as defined by Modification of Diet in Renal Disease (MDRD) method from National Kidney Disease Education Program (NKDEP) Serum creatinine =< 1.5 mg/dL; if serum creatinine > 1.5 mg/dL, then the estimated glomerular filtrate rate (GFR) must be > 60 ml/min/1.73 m^2 as calculated by the Modification of Diet in Renal Disease equation Subject has an estimated glomerular filtration rate (eGFr) of < 60ml/min as calculated by the modification of diet Renal disease (MDRD) Equation. Creatinine (Cr) clearance > 50 mL/min by Modification of Diet in Renal Disease (MDRD) calculation Serum creatinine < 1.5 x institutional ULN or an estimated glomerular filtration rate (eGFR) of > 50 ml/min as calculated by the Modification of Diet in Renal Disease (MDRD) equation. Estimated serum creatinine clearance >= 50 ml/min (Modification of Diet in Renal Disease [MDRD] method from National Kidney Disease Education Program, [NKDEP]) and/or serum creatinine =< 1.8 mg/dL Calculated creatinine clearance by Modification of Diet in Renal Disease (MDRD) (CrCL) > 50 ml/min/1.73 squared meter Calculated creatinine clearance (CrCl) >= 50 mL/min (modification of diet in renal disease [MDRD] Formula) Creatinine clearance >= 30 mL/min by Modified Diet in Renal Disease (MDRD) equation or Cockcroft-Gault Renal function at screening and enrollment as defined by the Modification of Diet in Renal Disease (MDRD) equation. Calculated creatinine clearance < 30 ml/min; creatinine clearance will be calculated using the Modification of Diet in Renal Disease (MDRD) method Serum creatinine ? 2 times upper limits of normal or estimated glomerular filtration rate ? 60 mL/min/1.73 meter squared per Modification of Diet in Renal Disease equation (MDRD) Renal insufficiency, preferably determined by creatinine clearance less than (<)40 milliliter per minute (mL/min) measured or estimated using the Modification of Diet in Renal Disease (MDRD), or serum creatinine >177 micromole per liter (?mol/L) Serum creatinine =< 1.5 x the upper limit of normal (ULN) or an estimated glomerular filtration rate (eGFR) calculated using the modification of diet in renal disease (MDRD) equation of at least 45 mL/min/1.73 m^2 Serum creatinine ? 1.5 x institutional upper limit of normal (ULN), or if serum creatinine outside normal range, then glomerular filtration rate (GFR) > 40 mL/min/1.73m^2 as calculated with the 4-parameter Modification of Diet in Renal Disease (MDRD) equation. Renal failure, as determined by estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73 m^2 by the Modification of Diet in Renal Disease (MDRD) model based on a serum creatinine level obtained within 28 days prior to enrollment