Subject has given written informed consentXx_NEWLINE_xXPatient must have given written informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXWritten informed consent must be obtained prior to any screening proceduresXx_NEWLINE_xXSigned written informed consent obtained prior to performing any study procedure, including pre-screening and screening procedures.Xx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXDocumented informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consent must be obtained prior to any screening procedures other than procedures performed as part of standard of care.Xx_NEWLINE_xXExecute an informed consent.Xx_NEWLINE_xXWritten informed consent must be obtained prior to any screening procedures and according to local guidelinesXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXProvided informed consentXx_NEWLINE_xXEvidence of a signed informed written consentXx_NEWLINE_xXWritten informed consent has been obtainedXx_NEWLINE_xXHas read and understands the informed consent form and has given written informed consent prior to any study proceduresXx_NEWLINE_xXWritten informed consent prior to any procedure.Xx_NEWLINE_xXHas provided signed written informed consentXx_NEWLINE_xXSigned written informed consent obtained prior to study proceduresXx_NEWLINE_xXWritten informed consent must be obtained prior to any screening proceduresXx_NEWLINE_xXAble to understand and give written informed consent and comply with study procedures.Xx_NEWLINE_xXInformed consent providedXx_NEWLINE_xXProvides written informed consent on the approved informed consent formXx_NEWLINE_xXProvision of signed written informed consentXx_NEWLINE_xXWritten informed consent provided prior to the initiation of study proceduresXx_NEWLINE_xXSigned written informed consent.Xx_NEWLINE_xXWritten informed consent provided.Xx_NEWLINE_xXUnwillingness to give written informed consentXx_NEWLINE_xXProvided written informed consentXx_NEWLINE_xXHas provided written informed consent for participation in this trialXx_NEWLINE_xXSubject has provided written informed consentXx_NEWLINE_xXSigned written informed consent.Xx_NEWLINE_xXAbility to give written informed consentXx_NEWLINE_xXSubjects given written informed consentXx_NEWLINE_xXGive informed consentXx_NEWLINE_xXThe subject must sign a written informed consent form prior to the initiation of any study procedures. Adult subjects unable to provide written informed consent on their own behalf will not be eligible for the studyXx_NEWLINE_xXProvision of written informed consentXx_NEWLINE_xXInformed consent for participationXx_NEWLINE_xXWritten informed consent must be obtained from the patient.Xx_NEWLINE_xXWilling to and capable of providing written informed consent prior to any study related proceduresXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consent.Xx_NEWLINE_xXHave provided written informed consentXx_NEWLINE_xXSigned written informed consent obtained prior to study proceduresXx_NEWLINE_xXWritten informed consent (or assent/ parental consent for minor subjects) prior to any screening proceduresXx_NEWLINE_xXWritten informed consent obtained from the subject prior to performing any protocol-related proceduresXx_NEWLINE_xXMust be able to give informed consent; subjects unable to give informed consent will not be eligible for this studyXx_NEWLINE_xXMust have provided written informed consent prior to participating in any study-related activity.Xx_NEWLINE_xXWritten informed consent.Xx_NEWLINE_xXsigned written informed consent obtained prior to study proceduresXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXHave signed written informed consentXx_NEWLINE_xXProvision of signed written informed consent.Xx_NEWLINE_xXHave provided written informed consent.Xx_NEWLINE_xXPRE-SCREENING: Written informed consent for prescreeningXx_NEWLINE_xXFULL STUDY INCLUSION CRITERIA: Written informed consent for full studyXx_NEWLINE_xXWritten informed consent obtained prior to any screening proceduresXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consent obtained prior to biopsies and blood samplesXx_NEWLINE_xXWritten informed consent obtained prior to biopsies and blood samplesXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent; a signed informed consent must be obtained prior to any study specific proceduresXx_NEWLINE_xX>=18 years of age and provided signed written informed consentXx_NEWLINE_xXProvision of written informed consent to participate in this investigational studyXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXSigned, written informed consentXx_NEWLINE_xXWritten informed consent obtained prior to any study-related procedure being performed.Xx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXSubjects must have signed written, informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXWritten informed consent for transplantXx_NEWLINE_xXInformed consentXx_NEWLINE_xXHas given written consent to participate in the study.Xx_NEWLINE_xXSigned, written informed consentXx_NEWLINE_xXWritten informed consent is givenXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXPatient has given written informed consent.Xx_NEWLINE_xXSigned written informed consent must be obtained prior to any study procedures.Xx_NEWLINE_xXInformed consentXx_NEWLINE_xXSubjects must have signed written, informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consent for the protocol must be obtained prior to any screening proceduresXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXWritten informed consent from patient or legal representativeXx_NEWLINE_xXDONOR: Written informed consentXx_NEWLINE_xXSigned, written, informed consentXx_NEWLINE_xXWritten and signed informed consent from the parent(s) or legal representative (guardian) and assent from the minor participant. Written informed consent from subjects ?18 years.Xx_NEWLINE_xXAbility to give written informed consentXx_NEWLINE_xXPatients must give informed consentXx_NEWLINE_xXWritten informed consent must be obtained prior to any screening proceduresXx_NEWLINE_xXSubjects must give written informed consent to participate in this trialXx_NEWLINE_xXAbility to understand and willingness to sign a written informed consent; a signed informed consent must be obtained prior to any study specific proceduresXx_NEWLINE_xXWritten informed consent obtainedXx_NEWLINE_xXProvision of written informed consentXx_NEWLINE_xXProvision of written informed consent prior to any screening proceduresXx_NEWLINE_xXHas provided written informed consent prior to completing any study proceduresXx_NEWLINE_xXWritten informed consent is givenXx_NEWLINE_xXSubjects given written informed consentXx_NEWLINE_xXPatient should be able to provide signed written informed consent; before any study procedures are performed, subjects will have the details of the study described to them, and they will be given a written informed consent document to read; then, if subjects consent to participate in the study, they will indicate that consent by signing and dating the informed consent document in the presence of study personnel; written consent will include a Health Insurance Portability and Accountability Act (HIPAA) form according to institutional guidelinesXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consent must be obtained from all patients prior to any study proceduresXx_NEWLINE_xXProvision of written informed consentXx_NEWLINE_xXSubjects given written informed consentXx_NEWLINE_xXInformed consentXx_NEWLINE_xXHave provided informed consentXx_NEWLINE_xXInformed consent must be obtainedXx_NEWLINE_xXInformed ConsentXx_NEWLINE_xXWritten informed consent obtained prior to any study-related procedure being performed;Xx_NEWLINE_xXWritten informed consent must be obtained prior to any procedures unless considered standard of care.Xx_NEWLINE_xXWritten informed consent for the trialXx_NEWLINE_xXPatients must give informed consentXx_NEWLINE_xXWritten informed consent prior to admission to this studyXx_NEWLINE_xXPatients must give written informed consent prior to registration on the studyXx_NEWLINE_xXInformed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXHave signed a written informed consentXx_NEWLINE_xXWritten informed consent prior to initiation of any study-related procedures;Xx_NEWLINE_xXAble to give written informed consent to participate in the studyXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXHas read and understands the informed consent form and has given written informed consent prior to any study procedures.Xx_NEWLINE_xXHas provided written informed consent, and has the willingness and ability to comply with all study proceduresXx_NEWLINE_xXWritten informed consent obtained from subject prior to any protocol related proceduresXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXWritten informed consent providedXx_NEWLINE_xXSigned written informed consent.Xx_NEWLINE_xXPatients must give informed consentXx_NEWLINE_xXInformed consentXx_NEWLINE_xXAbility to give written informed consentXx_NEWLINE_xXWritten informed consent must be obtained prior to any screening procedures and according to local guidelinesXx_NEWLINE_xXWritten informed consent must be obtained prior to any screening procedures and according to local guidelinesXx_NEWLINE_xXCapable of giving written informed consentXx_NEWLINE_xXPatient’s written informed consentXx_NEWLINE_xXInability to give informed written consentXx_NEWLINE_xXInability to give informed written consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXSigned written informed consent and assent forms (if applicable) must be obtained prior to any study proceduresXx_NEWLINE_xXWritten informed consent must be obtained prior to any screening proceduresXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXWritten Informed ConsentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consent for the transplant phaseXx_NEWLINE_xXWritten informed consent to participate in this study before the performance of any study-related procedureXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXwritten informed consent obtained prior to any study-related procedures.Xx_NEWLINE_xXPatient must give written informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consent is givenXx_NEWLINE_xXObtained written informed consentXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent; a signed informed consent must be obtained prior to any study specific proceduresXx_NEWLINE_xXWritten informed consent must be obtained before any assessment is performed.Xx_NEWLINE_xXSubjects >=18 years of age and provided signed written informed consent.Xx_NEWLINE_xXWritten informed consent to participate in this studyXx_NEWLINE_xXProvided written consentXx_NEWLINE_xXPatient must give written informed consentXx_NEWLINE_xXInformed consentXx_NEWLINE_xXDocumented informed consentXx_NEWLINE_xXWritten informed consent prior to any procedureXx_NEWLINE_xXWritten informed consent providedXx_NEWLINE_xXSigned, written informed consentXx_NEWLINE_xXGive informed consentXx_NEWLINE_xXSigned, written, informed consentXx_NEWLINE_xXWritten informed consent must be obtained prior to any screening proceduresXx_NEWLINE_xXSigned written informed consent.Xx_NEWLINE_xXWritten informed consent obtained from the patient/legal representative;Xx_NEWLINE_xXSubjects must give written informed consent to participate in this trialXx_NEWLINE_xXWritten informed consent must be obtainedXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consent obtained from the patient/legal representativeXx_NEWLINE_xXSigned written informed consent for this protocolXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent; a signed informed consent must be obtained prior to any study specific proceduresXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXSigned, written informed consent.Xx_NEWLINE_xXWritten informed consent.Xx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consent must be obtained from all patients before entry into the studyXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXWritten informed consent must be obtained prior to any study-related proceduresXx_NEWLINE_xXSigned written informed consent grantedXx_NEWLINE_xXWritten informed consent obtained prior to any screening procedures performedXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXSigned, written informed consentXx_NEWLINE_xXWritten informed consent obtained prior to any screening proceduresXx_NEWLINE_xXWillingness and ability to give signed written informed consentXx_NEWLINE_xXHave given written informed consent prior to any study proceduresXx_NEWLINE_xXInformed consentXx_NEWLINE_xXPatient should be able to provide signed written informed consent:\r\n* Before any study procedures are performed, subjects will have the details of the study described to them, and they will be given a written informed consent document to read; then, if subjects consent to participate in the study, they will indicate that consent by signing and dating the informed consent document in the presence of study personnel\r\n* Written consent will include a Health Insurance Portability and Accountability Act (HIPAA) form according to institutional guidelinesXx_NEWLINE_xXWritten informed consent has been obtainedXx_NEWLINE_xXPatient's Informed Consent. -Xx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXInformed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXWritten informed consent prior to registration on studyXx_NEWLINE_xXSigned written informed consent;Xx_NEWLINE_xXHas given written Informed ConsentXx_NEWLINE_xXPatients must give written informed consentXx_NEWLINE_xXHas provided signed written informed consent for this studyXx_NEWLINE_xXSigned written informed consent.Xx_NEWLINE_xXSigned written informed consent.Xx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent; a signed informed consent must be obtained prior to any study specific proceduresXx_NEWLINE_xXSigned, written informed consentXx_NEWLINE_xXAbility to understand and willingness to sign a written informed consent; a signed informed consent must be obtained prior to any study specific proceduresXx_NEWLINE_xXSigned Written Informed Consent\r\n* Before any study procedures are performed, subjects will have the details of the study described to them, and they will be given a written informed consent document to read; then, if subjects consent to participate in the study, they will indicate that consent by signing and dating the informed consent document in the presence of study personnel\r\n* Written consent will include a Health Insurance Portability and Accountability Act (HIPAA) form according to institutional guidelinesXx_NEWLINE_xXWritten informed consent and assent as is age appropriateXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXsigned written informed consentXx_NEWLINE_xXAbility to understand informed consent and signing of written informed consent document prior to initiation of protocol therapyXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent. A signed informed consent must be obtained prior to any study specific procedures.Xx_NEWLINE_xXWritten consent by the participantXx_NEWLINE_xXWritten Informed ConsentXx_NEWLINE_xXWritten informed consent must be provided.Xx_NEWLINE_xXProvided signed written informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXWritten informed consent must be obtained prior to any screening proceduresXx_NEWLINE_xXPatients must give informed consentXx_NEWLINE_xXProvided signed written informed consentXx_NEWLINE_xXProvision of written informed consentXx_NEWLINE_xXAble to understand and give written informed consent and comply with study procedures.Xx_NEWLINE_xXWritten informed consent or assentXx_NEWLINE_xXHas given written informed consent.Xx_NEWLINE_xXPatients capable of providing written, informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXWritten and signed informed consent must be obtainedXx_NEWLINE_xXSubjects must give written informed consent to participate in this trialXx_NEWLINE_xXAble to understand and give written informed consent and comply with study procedures.Xx_NEWLINE_xXWritten informed consent to participate in this study before the performance of any study-related procedureXx_NEWLINE_xXSigned written informed consent obtained prior to performing any study procedure, including screening procedures.Xx_NEWLINE_xXInformed consentXx_NEWLINE_xXWilling and able to understand and provide written informed consent. For minors or those incapable of providing written informed consent (i.e., incapacitated), understood, written and informed consent must be provided by a parent or legal guardian or representative.Xx_NEWLINE_xXAbility to give written informed consent and willing to comply with the requirements of the protocol; and for Part 3, to give written informed consent for 2 cancer biopsy proceduresXx_NEWLINE_xXSigned written informed consent.Xx_NEWLINE_xXPatient must have the ability to give written informed consentXx_NEWLINE_xXWritten informed consent;Xx_NEWLINE_xXHave signed written informed consentXx_NEWLINE_xXProvision of written informed consentXx_NEWLINE_xXpatient had given written informed consent.Xx_NEWLINE_xXWritten informed consent obtained before undergoing any study-related activitiesXx_NEWLINE_xXSigned, written informed consent.Xx_NEWLINE_xXSigned written informed consent.Xx_NEWLINE_xXHas provided written informed consent prior to any study related activities.Xx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXHas the subject given written informed consent?Xx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consent provided.Xx_NEWLINE_xXPatients must have a written informed consent obtained prior to the initiation of study proceduresXx_NEWLINE_xXHas provided written informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consent has been obtainedXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXPatients who give a written informed consentXx_NEWLINE_xXWritten voluntary informed consent: the patient is capable of complying with the requirements of the written Informed Consent Form and complying with protocol requirementsXx_NEWLINE_xXSigned written informed consent providedXx_NEWLINE_xXWritten informed consent - a signed informed consent and/or assent (as age appropriate) for study participation including PK sampling will be obtained according to institutional guidelines.Xx_NEWLINE_xXWritten informed consent - a signed informed consent and/or assent (as age appropriate) will be obtained according to institutional guidelines.Xx_NEWLINE_xXSigned Written Informed ConsentXx_NEWLINE_xXAbility to give written informed consent.Xx_NEWLINE_xXWritten informed consent.Xx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXPatients must give written informed consentXx_NEWLINE_xXProvision of written informed consent.Xx_NEWLINE_xXSubjects must have given written informed consent to agree to participateXx_NEWLINE_xXSubjects must have given written informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXMust sign a written informed consent,Xx_NEWLINE_xXHave the ability to give written informed consentXx_NEWLINE_xXWritten informed consent signed prior to entry into the studyXx_NEWLINE_xXInformed consentXx_NEWLINE_xXWritten informed consent and any locally required authorizationXx_NEWLINE_xXWritten informed consent must be obtained prior to any proceduresXx_NEWLINE_xXSubjects given written informed consent.Xx_NEWLINE_xXWritten, informed consentXx_NEWLINE_xXWritten informed consent.Xx_NEWLINE_xXDocumented written informed consent of the participantXx_NEWLINE_xXHSCT CGs: Able to give written informed consentXx_NEWLINE_xXSubjects who cannot give an informed consentXx_NEWLINE_xXHas provided written informed consentXx_NEWLINE_xXWritten, informed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXMust give written study consentXx_NEWLINE_xXAny patient with cholestasis due to suspected MHO who provides written informed consent.Xx_NEWLINE_xXWritten informed consent prior to any study-related proceduresXx_NEWLINE_xXAll subjects must have the ability to understand and the willingness to participate in the informed consent process, although a waiver of written informed consent is obtained for this studyXx_NEWLINE_xXPatients must give informed consentXx_NEWLINE_xXProperly obtained written informed consentXx_NEWLINE_xXGives written informed consentXx_NEWLINE_xXGives written informed consentXx_NEWLINE_xXCannot give informed consent.Xx_NEWLINE_xXAll patients to give written informed consent to participateXx_NEWLINE_xXSigned, written informed consentXx_NEWLINE_xXUnable to give written informed consentXx_NEWLINE_xXWritten informed consent obtained prior to any study-related procedure being performed;Xx_NEWLINE_xXProvision of written informed consent to participate in this investigational studyXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent; a signed informed consent must be obtained prior to any study specific proceduresXx_NEWLINE_xXWritten informed consent prior to any study-related proceduresXx_NEWLINE_xXGive written informed consentXx_NEWLINE_xXParticipants must be capable of providing written informed consent for study participationXx_NEWLINE_xXProperly obtained written informed consentXx_NEWLINE_xXInformed consentXx_NEWLINE_xXSigned written informed consent prior to inclusion in the study.Xx_NEWLINE_xXAble to perform written, informed consentXx_NEWLINE_xXWritten consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXGiven written informed consent (patient and donor)Xx_NEWLINE_xXParticipants must have a signed written informed consentXx_NEWLINE_xXSubjects who cannot give an informed consentXx_NEWLINE_xXPatients must give written informed consent to participate in this study before the performance of any study-related procedure.Xx_NEWLINE_xXSubject must have provided written Informed ConsentXx_NEWLINE_xXWritten informed consent obtained from the subject.Xx_NEWLINE_xXWritten informed consent obtained from the subjectXx_NEWLINE_xXUnable to give written, informed consentXx_NEWLINE_xXPatients cannot give informed consent.Xx_NEWLINE_xXPatient provides written informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXInformed consentXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xXInformed consentXx_NEWLINE_xXGive written informed consentXx_NEWLINE_xXHave been informed of the nature of the study and provided written informed consent, prior to initiation of any study activities;Xx_NEWLINE_xXPatient provides written informed consentXx_NEWLINE_xXPatient provides written informed consentXx_NEWLINE_xXPatients must give written informed consentXx_NEWLINE_xXAble to give written informed consent to participate in the studyXx_NEWLINE_xXProvides written informed consentXx_NEWLINE_xXPatients who cannot give informed consentXx_NEWLINE_xXSigned, written informed consentXx_NEWLINE_xXThe subject must sign a written informed consent form prior to the initiation of any study procedures. Adult subjects unable to provide written informed consent on their own behalf will not be eligible for the study.Xx_NEWLINE_xXWilling to and capable of providing written informed consent prior to any study related proceduresXx_NEWLINE_xXProvides written informed consent documentXx_NEWLINE_xXPatients who have granted written informed consent for the studyXx_NEWLINE_xXWritten informed consent will be obtained from patientsXx_NEWLINE_xXProvides written informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXProvides written informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXProvides written informed consentXx_NEWLINE_xXProvides written informed consentXx_NEWLINE_xXWritten informed consentXx_NEWLINE_xXInformed consent was obtained.Xx_NEWLINE_xXAll patients must give written informed consentXx_NEWLINE_xXWritten informed consent.Xx_NEWLINE_xXAbility to understand informed consent and signing of written informed consent prior to initiation of protocol therapyXx_NEWLINE_xXProvides written informed consentXx_NEWLINE_xXSubject has provided written informed consent to participate in the studyXx_NEWLINE_xXSubject has provided written informed consent to participate in the studyXx_NEWLINE_xXWritten informed consent must be obtained prior to any baseline/screening procedures.Xx_NEWLINE_xXSigned Written Informed ConsentXx_NEWLINE_xXWritten informed consent will be signed by the patients before the MRI examinationXx_NEWLINE_xXSubjects incapable of giving informed written consentXx_NEWLINE_xXProvision of written informed consentXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent. A signed informed consent, including consent for biomarker analyses, must be obtained prior to any study-specific proceduresXx_NEWLINE_xXSigned written informed consentXx_NEWLINE_xX