The Quality of Life and Economic Substudy is permanently closed to accrual effective 12/1/12; patients who consented to QOL prior to 12/1/12 should continue to complete QOL forms per their expectation report; patients who are able to complete a questionnaire in English must be offered the opportunity to participate in the Quality of Life and Economic Substudy; (The Quality of Life and Economic Substudy is available to U.S. INSTITUTIONS ONLY); patients who are not able to complete a questionnaire in English are registered to S1007 without participating in the Quality of Life and Economic Substudy* Patients who consent to participate in the Quality of Life and Economic Substudy and who do not yet know the results of their Oncotype DX screening must agree to complete the S1007 Health-Related Quality of Life Questionnaire: Enrollment between 14 days prior to and 7 days after Step 1 Registration* Patients who consent to participate in the Quality of Life and Economic Substudy and who do already know their Oncotype DX Recurrence Score (and it is 25 or less) will proceed to Step 2 Registration without completing the S1007 Health-Related Quality of Life Questionnaire Enrollment Form (but will complete the S1007 Health-Related Quality of Life Questionnaire: Randomized Study Form)
The Quality of Life and Economic Substudy is permanently closed to accrual effective 12/1/12; patients at U.S. INSTITUTIONS who consent to participate in the Quality of Life and Economic Substudy must agree to complete the S1007 Health-Related Quality of Life Questionnaire: Randomized Study Form after Recurrence Score results and randomized treatment status are known but before treatment has been initiated
Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life
Therapeutic options: patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life
Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life
Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life
Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life
Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life
Patients current disease state must be one for which there is no known curative therapy or therapy proven to prolong survival with an acceptable quality of life
Patients current disease state must be one for which there is no known curative therapy