Renal dysfunction for which exposure to cisplatin would be unsafe or require cisplatin dose modification (i.e., creatinine [Cre] > 1.5 mg/dl or glomerular filtration rate [GFR] < 60 cc/min)
Adequate renal function (within normal limits or calculated glomerular filtration rate >50)
Patients with renal insufficiency with an estimated glomerular filtration (EGF) <= 30 are excluded, due to they will not be able to undergo gadolinium enhance MRI.
Renal failure; exception: if GFR (glomerular filtration rate) is > 20%, a patient with renal failure can be included in the study
Ineligible for cisplatin as defined by presence of one or more of the following:\r\n* Impaired renal function (glomerular filtration rate [GFR] >= 30 but =< 60 cc/min); GFR should be assessed by direct measurement (i.e. creatinine clearance or ethylenediaminetetra-acetate) or, if not available, by calculation from serum/plasma creatinine by Cockroft-Gault equation\r\n* Grade >= 2 hearing loss (measured by loss of > 25 dB at two contiguous frequencies in at least one ear)\r\n* Grade >= 2 peripheral neuropathy\r\n* ECOG performance status of 2\r\n* Solitary kidney
Glomerular filtration rate (GFR) adequate for intravenous (IV) contrast delivery for imaging
For patients who agree to participate in PET/MR imaging:\r\n* Renal insufficiency (glomerular filtration rate [GFR] < 30 mL/min/1.73 m^2) measured within the past 60 days which precludes safe administration of the contrast agent\r\n* On dialysis\r\n* Prior allergic reaction to gadolinium-based MR contrast agents
Renal (glomerular filtration rate [GFR] > 40) contraindications for high dose chemotherapy
Renal-calculated or measured glomerular filtration rate (GFR) < 40 ml/min, dialysis requirement, or prior renal transplant
Patients with renal failure (GFR < 50 mL/min) are excluded
Acute or chronic severe renal insufficiency (Glomerular filtration rate (GFR) <30ml/min/1.73 sq.meters)
Renal insufficiency defined as estimated glomerular filtration rate of < 60 or hepatic insufficiency defined as transaminitis or hyperbilirubinemia of > 1.5 times the highest normal value
Patients >= 65 years without underlying renal insufficiency get GFR tested within 6 months of the exam.
Patients < 65 years without underlying renal insufficiency do not require an GFR calculation.
Patients >= 65 years with known underlying renal insufficiency get GFR tested within 1 month of the exam.
Patients < 65 years with known renal insufficiency get GFR tested within 1 month of the exam.
Participants with renal insufficiency or failure, as determined by glomerular filtration rate (GFR) < 60 mL/min/1.73 m^2, performed for all patients within 24 hours of the imaging exams
Individuals with end stage renal disease, known glomerular filtration rate (GFR) < 25, current or anticipated dialysis or transplant within the next two years will be excluded; a history of renal transplant is not an exclusion per se if patient does not meet stated renal criteria
Patient has a glomerular filtration rate (GFR) > 60. In patients with moderate renal failure (GFR 30-60), an alternate injection with 2 times half-dose multihance (gadobenate dimeglumine) or gadovist (gadobutrol) will be considered, if a contrast exam is deemed clinically necessary.
Patients with an estimated glomerular filtration rate (eGFR) =< 30 will be excluded to avoid issues related to contrast administration in such patients; this glomerular filtration rate (GFR) threshold cutoff level is chosen per institutional policy, because below that level other measures would be required (hydration or no contrast administration); in order to keep the imaging information as uniform as possible in such a small study group, patients with a low GFR will not be enrolled in the study
Patients with moderate to end-stage renal (kidney) disease, defined as a glomerular filtration rate (GFR) less than 30 mL/day/1.73m^2
Patients with renal failure, defined as glomerular filtration rate (GFR) < 60 at the time of the radiation treatment-planning (RTP) scan, will be excluded
Patients with severe chronic renal insufficiency (glomerular filtration rate < 30 mL/min/1.73 m^2), hepatorenal syndrome or post-liver transplantation
Renal insufficiency: glomerular filtration rate (GFR) < 40ml/min/1.73) and following European Society of Urogenital Radiology (ESUR) guidelines (exclusion criterion only for contrast enhanced MRI)
Participants with diagnosis of renal insufficiency or glomerular filtration rate (GFR) < 60 ml/min/1.73m^2
Contraindications for MRI with contrast or PET/CT including:\r\n* Cardiac pacemaker, implanted cardiac defibrillator, pacing wires, internal electrodes\r\n* Aneurysm clips\r\n* Cochlear, otologic, or other ear implant\r\n* Tissue expander\r\n* Swan-Ganz or thermodilution\r\n* Moderate renal insufficiency (estimated glomerular filtration rate [GFR] less than 60 mL/min/1.73 m^2) to end stage renal disease (estimated GFR less than 15 mL/min/1.73 m^2 or a serum creatinine more than 3 mg/dL), who are not on dialysis, and patients with renal failure on chronic dialysis\r\n* Severe claustrophobia
Patients with renal insufficiency with a glomerular filtration rate (GFR) < 30
Patients with renal insufficiency; glomerular filtration rate (GFR) < 60
Patients with renal insufficiency; glomerular filtration rate (GFR) < 60
Normal creatinine and estimated glomerular filtration rate (GFR) within 30 days under the following circumstances:\r\n* Had abnormal creatinine in the last 60 days\r\n* Are over 60 years of age\r\n* Has received chemotherapy within the past 30 days\r\n* Has diabetes, human immunodeficiency virus (HIV), renal disease or history (hx) of renal cancer
Renal dysfunction as defined as a glomerular filtration rate (GFR) < 70
Unable to receive a PET-MRI scan due to renal function (glomerular filtration rate [GFR] < 30 mL/min/1.73 m^2), allergy, or other problem with receiving or tolerating an MRI scan, etc. all patients will fill out a standard MRI screening form
If agreeing to MRI contrast, participant must not have renal insufficiency (glomerular filtration rate [GFR] < 30 mL/min/1.73 m^2) measured within the past 60 days
Severe renal insufficiency (GFR ? 29).
Subjects with renal insufficiency; glomerular filtration rate (GFR) < 50
Renal insufficiency (defined as glomerular filtration rate [GFR] < 30 mL/min/1.73 m^2) measured no more than 60 days before the first research scan) which precludes safe administration of the contrast agent
Creatinine clearance and/or glomerular filtration rate (GFR) greater than or equal to 60 mL/min/1.73m^2 within 21 days of protocol therapy; kidney function cannot be estimated by other means
INCLUSION - TREATMENT: Estimated glomerular filtration rate (GFR) > 60 mL/min
TREATMENT INCLUSION: Estimated glomerular filtration rate (GFR) > 70 mL/min
Glomerular filtration rate (GFR) ? 30 mL/min/1.73 m2 using the MDRD-4 variable formula
Estimated glomerular filtration rate (GFR by Cockroft-Gault equation OR 24 hour urine collection >= 60 ml/min
Impaired kidney function requiring dialysis or glomerular filtration rate (GFR) < 40mL/min (estimated or calculated)
Glomerular filtration rate ? 60 ml/min
Estimated glomerular filtration rate (GFR) > 50 mL/min
Calculated or measured glomerular filtration rate (GFR) < 30 ml/min, dialysis requirement, or prior renal transplant
Within 28 days prior to treatment start: Serum creatinine glomerular filtration rate (GFR) > 45 mL/min
Glomerular filtration rate (GFR) >= 45 mL/min
Within two weeks prior to enrollment: Serum creatinine which is less than 1.5 times the upper limit of institutional normal for age or glomerular filtration rate (GFR) > 70 ml/min/1.73m^2
Glomerular filtration rate (GFR) > 60 mL/min
Estimated GFR >30mL/min/1.73m2
Having an estimated glomerular filtration rate (GFR) < 40 ml/min/1.73 m^2.
Serum creatinine =< 1.5 x ULN or estimated glomerular filtration rate (GFR) >= 50 mL/min/m^2
Estimated creatinine clearance or GFR (glomerular filtration rate) >= 50 mL/min
Glomerular filtration rate (GFR) > 50 ml/min/1.73 m^2 or serum creatinine =< 2.5 x upper limit of normal (ULN) for age
Glomerular Filtration Rate (GFR) <40 ml/min
Glomerular filtration rate (GFR) >= 45 mL/min
Creatinine > 1.5 x ULN or glomerular filtration rate (GFR) < 45 mL/min
Abnormal kidney function (glomerular filtration rate GFR < 45 mL/min)
For patients >= 1.0 year of age but < 13.0 years of age at the time of enrollment: glomerular filtration rate (GFR) estimated by the updated Schwartz formula >= 90 mL/min/1.73 m^2; if the estimated GFR is < 90 mL/min/1.73 m^2, then renal function must be measured by 24-hour creatinine clearance or nuclear GFR, and must be > 50 mL/min/1.73 m^2
Creatinine clearance (CrCl) or glomerular filtration rate (GFR) >= 50 ml/min/1.73 m^2
Estimated GFR < 40 ml/min
Glomerular filtration rate (GFR) >= 45 mL/min
Glomerular filtration rate (GFR) < 30 ml/min/1.73 m^2 (if receiving contrast for MRI)
Creatinine =< 1.5 x IULN OR glomerular filtration rate (GFR) of >= 50 mL/min
Serum creatinine =< 2 x ULN or glomerular filtration rate (GFR) >= 50
Glomerular filtration rate (GFR) > 50 ml/min/1.72 m^2 or creatinine < 2 g/dL, values =< 2 weeks
Estimated or actual glomerular filtration rate (GFR) > 40 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal; GFR should be corrected for body surface area (BSA)
Estimated glomerular filtration rate (GFR) > 30 ml/min
Glomerular filtration rate (GFR) > 59
Glomerular filtration rate (GFR) >= 45 mL/min
Glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2
Creatinine clearance or glomerular filtration rate (GFR) >= 60 ml/min
Glomerular filtration rate > 60 ml/min/1.73 m^2
Glomerular filtration rate (GFR) at Screening < 40 milliliter (mL)/minute (min)
Adequate renal function (estimated glomerular filtration rate [GFR] > 40mL/min)
Within 14 days of study registration (30 days for pulmonary and cardiac): estimated glomerular filtration rate (GFR) >= 40 mL/min/1.73m^2
Glomerular filtration rate (GFR) or creatinine clearance (CrCl) (24 hour urine) greater than 30 ml/min corrected for body surface area
Estimated glomerular filtration rate (GFR) of >= 50 ml/min (based on the Fairview Laboratories formula at time of screening)
Estimated or actual glomerular filtration rate (GFR*) > 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal\r\n* GFR should be corrected for body surface area (BSA)
Glomerular Filtration Rate (GFR) > 40mL (milliliter)/min; Creatinine ? 1.5 x ULN (Upper limit of Normal)
Glomerular filtration rate (GFR) > 30 mL/min (by standard Cockcroft and Gault formula or measured via 24 hour urine collection)
Serum creatinine =< 2 x ULN or glomerular filtration rate (GFR) >= 50
Glomerular filtration rate (GFR) > 25 ml/min (for patients receiving cisplatin, GFR >= 60 ml/min)
Creatinine > 1.5 ULN or glomerular filtration rate (GFR) < 45 ml/min
Creatinine =< 1.5 or glomerular filtration rate (GFR) >= 60 mL/min/1.73m^2
Adequate renal function with estimated glomerular filtration rate (GFR) by Cockcroft Gault of greater than 40 ML per minute
Creatinine < 1.5 x the ULN or glomerular filtration rate (GFR) < 45 ml/min
Glomerular filtration rate (GFR) > 50 mL/min
Glomerular filtration rate ? 50 mL/min;
Glomerular filtration rate (GFR) =< 50
Estimated glomerular filtration rate (GFR) > 50 ml/min
Creatinine clearance or glomerular filtration rate (GFR) greater than or equal to 50 mL/min/1.73 m^2
Calculated glomerular filtration rate (GFR) > 45 mL/min
Estimated glomerular filtration rate (GFR) must be >= 50 mL/min
Estimated glomerular filtration rate (GFR) >= 50 mL/min/1.73m^2
Glomerular filtration rate (GFR) >= 30 ml/min/1.73m^2
Serum creatinine which is less than 1.5 x the upper limit of institutional normal for age or glomerular filtration rate (GFR) > 70 ml/min/1.73 m^2 within two weeks prior to enrollment
Glomerular filtration rate (GFR) > 30 using Cockcroft–Gault formula
Creatinine >= 1.5 x upper limit of normal (ULN) or glomerular filtration rate (GFR) < 45 ml/min
Estimated glomerular filtration rate (GFR) > 45 mL/min/1.73 m^2
Estimated GFR > 45 mL/min/1.73 m^2
Glomerular filtration rate > 60 ml/min
Calculated glomerular filtration rate (GFR) > 50 ml/min
Glomerular filtration rate > 60 ml/min/1.73 m^2
Glomerular filtration rate (GFR) of 50 ml/minute or greater (if elevated serum creatinine level > 1.5 x ULN)
Glomerular filtration rate (GFR) of 50 mL/min or greater
Glomerular filtration rate (GFR) < 60 mL/min/1.73 m^2 or calculated GFR < 60 mL/min/m^2 per Schwartz formula
Creatinine clearance (CrCl) or glomerular filtration rate (GFR) >= 50 ml/min/1.73m^2
Calculated glomerular filtration rate (GFR) >= 60 ml/min
Creatinine clearance (CrCL) or glomerular filtration rate (GFR) >= 50 ml/min/1.73 m^2
Calculated glomerular filtration rate (GFR) must be >= 60 ml/min; GFR will be calculated as needed per institutional guidelines
Glomerular filtration rate (GFR) > 45 mL/min/1.73m^2 according to the Cockcroft-Gault estimation.
Glomerular filtration rate (GFR) >= 50 ml/minute using Cockroft-Gault formula
Calculated creatinine, glomerular filtration rate (GFR) >= 30 cc/minute
Normal creatinine for age or glomerular filtration rate (GFR) >= 70/ml/min/1.73m^2
Glomerular filtration rate (GFR) > 40 ml/min/1.73m^2 or
Estimated glomerular filtration rate (GFR) > 30 ml/min
Creatinine 2 x ULN or glomerular filtration rate (GFR) > 50
Calculated glomerular filtration rate (GFR) > 50 ml/minute
Glomerular filtration rate (GFR) < 45 ml/min
Calculated Glomerular filtration rate ? 50 mL/min;
Glomerular filtration rate (GFR) >= 30 ml/min
Glomerular filtration rate (GFR) of >= 50 mL/min/1.73 m^2
Glomerular filtration rate (GFR) < 55 mL/min
Estimated glomerular filtration rate (GFR) of < 50 mL/min/1.73 m^2
Creatinine clearance or glomerular filtration rate (GFR) which is greater than or equal to 70 ml/min/1.73 m^2
Chronic kidney disease with glomerular filtration rate < 30 ml/min
Estimated glomerular filtration rate (GFR) >15 mL/min/1.73m2
Glomerular Filtration Rate (GFR) ? 30% (? 30 ml/min/1.73 m2)
Renal function defined as a calculated or measured glomerular filtration rate (GFR) >= 30 mL/min; for Arm F carboplatin and pemetrexed, GFR >= 45 mL/min
Glomerular filtration rate (GFR) < 30
Decreased glomerular filtration rate (GFR) (< 60 ml/min/1.73 m^2 as estimated by the revised Schwartz equation)
Participants must have normal organ and marrow function as defined by a glomerular filtration rate (GFR) >= 60 mL/min/1.73 m^2 to be performed per clinical protocol.
Glomerular filtration rate (GFR) > 40
Creatinine =< 1.5 x institutional upper limit of normal (ULN) (OR glomerular filtration rate [GFR] > 30 ml/min/1.73 m^2)
OR glomerular filtration rate (GFR) > 30 ml/min/1.73 m^2 obtained =< 45 days prior to randomization
Glomerular filtration rate (GFR) >= 60 ml/min
Estimated glomerular filtration rate (GFR) < 35 ml/min/1.73 m^2
Patients must have adequate renal function: glomerular filtration rate (GFR) > 30 mL/min/1.73 m^2; for the test-retest sub-study MRI, patients must have a GFR of > 60 mL/min/1.73m^2
Glomerular filtration rate < 60 ml/min/1.73 m^2
Patients with a glomerular filtration rate (GFR) < 30 ml/min are ineligible to receive intravenous contrast per standard magnetic resonance (MR) exclusion criteria
Severe kidney dysfunction (glomerular filtration rate [GFR] < 30 mL/min/1.73m^2)
Subjects with a calculated glomerular filtration rate (GFR) >= 60 mL/min/1.73 m^2
Subjects with a calculated glomerular filtration rate (GFR) > 60 mL/min/1.73 m^2
Elevated creatinine and/or glomerular filtration rate (GFR) < 40 ml/min/1.7 sqm (exclusion criterion only for contrast enhanced MRI)
Have a calculated glomerular filtration rate (GFR) =< 30 mL/min/1.73 m^2
Are receiving any form of renal replacement therapy or have a calculated glomerular filtration rate (GFR) < 30 mL/min/1.75 m²; results of serum creatinine testing will be reviewed for calculation of glomerular filtration rate (GFR); patients without a serum creatinine level drawn within the prior 3 months will have this drawn upon enrollment
Glomerular filtration rate (GFR) >= 40
Subjects with glomerular filtration rate (GFR) < 50
Glomerular filtration rate (GFR) > 30 ml/min
Baseline glomerular filtration rate (GFR) < 50 mL/min/1.73m^2
Glomerular filtration rate (GFR) < 50
In addition, patients with glomerular filtration rate (GFR) < 15 ml/min/1.73m^2 or who are on dialysis will be excluded from the study
Patients with glomerular filtration rate (GFR) < 15 ml/min/1.73 m^2 or who are on dialysis will be excluded from the study
Estimated glomerular filtration rate (GFR) >= 30 mL/min/1.73 m^2
GFR (glomerular filtration rate) < 30 on labs drawn within 6 weeks of imaging
Patients with glomerular filtration rates < 30 mL/min/1.73m^2
Estimated glomerular filtration rate (GFR) (using Cockcroft formula) less than 30 ml/min/1.73 m^2
Compromised renal function with estimated glomerular filtration rate (GFR) of < 30 ml/min/1.73m^2
Glomerular filtration rate (GFR) >= 35 mL/min estimated by Cockcroft-Gault or measured directly by 24 hour urine creatinine within 90 days prior to Step 1 registration
Serum creatinine (Scr) =< 1.5mg/dl; if the Scr > 1.5, patients may still be eligible if the calculated glomerular filtration rate (GFR) (Cockroft-Gault) is >= 40ml/minute
Serum creatinine ? 1.5 X ULN OR calculated glomerular filtration rate (GFR) by Cockcroft-Gault formula ? 50 mL/min
Renal function as follows: serum creatinine < 2.0 mg/dL (176.84 umol/L) and estimated glomerular filtration rate > 30 mL/min/1.73 m2.
Serum creatinine >1.5 x ULN and/or creatinine clearance or estimated glomerular filtration rate <30 mL/min
Serum creatinine =< 1.5 mg/dL or calculated glomerular filtration rate (GFR) >= 60 mL/min
Serum creatinine =< 1.5 mg/dL or calculated glomerular filtration rate (GFR) >= 50 mL/min
Serum creatinine =< 1.5 mg/dL or calculated glomerular filtration rate (GFR) >= 60 mL/min
Serum creatinine ? 1.5 mg/dL (or glomerular filtration rate ? 60 ml/min as determined by the Cockcroft-Gault equation)
Glomerular filtration rate (GFR) greater than or equal to 40 ml/min using the Cockcroft-Gault formula or serum creatinine less than or equal to 1.5 x upper limit of normal (ULN)
if serum creatinine > 3mg/dL, estimated glomerular filtration rate (GFR) ? 20 mL/min
Serum creatinine =< 1.5 mg/dL OR calculated glomerular filtration rate (GFR) >= 60 mL/min
Serum creatinine: < 1.5 mg/dL or calculated glomerular filtration rate (GFR) >= 75 cc/min; creatinine clearance (CrCl) by Cockcroft Gault will be used to estimate GFR
Creatinine =< 1.5 x IULN or glomerular filtration rate of >= 60 mL/min
Creatinine < 2.0 x ULN or estimated Glomerular Filtration Rate GFR [Cockcroft-Gault] > 30 mL/min
Pediatric population (patients < 18 years): creatinine within normal limits or calculated creatinine clearance >= 90 ml/min/1.73 m^2 as calculated by the Schwartz formula for estimated glomerular filtration rate (GFR)
Serum creatinine < 2.0 ULN OR an estimated glomerular filtration rate ? 30 mL/minute using the Cockroft-Gault formula.
Creatinine clearance or glomerular filtration rate >= 70 ml/min/1.73 m^2 (calculated or measured as appropriate for age and level of concern by treating medical doctor [MD])
Glomerular filtration rate (GFR) greater than or equal to 40 ml/min using the Cockcroft-Gault formula or serum creatinine less than or equal to 1.5 x ULN
Glomerular filtration rate (GFR) greater than or equal to 40 ml/min using the Cockcroft-Gault formula or serum creatinine less than or equal to 1.5 x upper limit of normal (ULN)
Creatinine < 1.5 x ULN or estimated glomerular filtration rate (GFR) >= 50 ml/min by Cockcroft-Gault
A serum creatinine based on age/gender, derived from the Schwartz formula for estimating glomerular filtration rate (GFR), per protocol-specified criteria.
Creatinine =< 1.6 mg/ml OR creatinine clearance (estimated glomerular filtration rate [eGFR]) >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal at the time DAC-THU and pembrolizumab treatment commences
Serum creatinine < 3.0 mg/dl or if elevated, a calculated glomerular filtration rate (GFR) of > 30 mL/min/1.73 m^2
Serum creatinine =< 1.5 mg/dL OR calculated glomerular filtration rate (GFR) >= 60 mL/min
Serum creatinine =< 2 mg/dL and estimated glomerular filtration rate or creatinine clearance >= 20 ml/min
Estimated creatinine clearance >= 30 mL/min (24 hour measured glomerular filtration rate [GFR] or modified Cockcroft Gault)
Creatinine ? 1.5 x upper limit of normal (ULN), or calculated glomerular filtration rate (GFR) > 40 mL/min (Cockcroft-Gault) if creatinine > 1.5x ULN
Serum creatinine level =< 1.5 mg/dL or estimated glomerular filtration rate >= 50 mL/min
Glomerular filtration rate (GFR) < 50 mL/min, as assessed using the standard methodology at the investigating center (i.e. Cockroft-Gault), or serum creatinine > 1.5 x ULN
Creatinine < 2 mg/dl (or a glomerular filtration rate > 60)
Serum creatinine =< 1.5 mg/dl or glomerular filtration rate > 50 ml/min
Creatinine =< 2.0 mg/dl (adults) and estimated glomerular filtration rate (GFR) >= 40 mL/min (pediatrics); adults with a creatinine > 1.2 mg/dl or a history of renal dysfunction must have estimated glomerular filtration rate (GFR) > 40 mL/min
Within 3 months of registration: Glomerular filtration rate (GFR) >= 45 mL/min; Cockcroft-Gault formula will be used to calculate creatinine clearance
Serum creatinine within 0.5-1.4 mg/dL, or if serum creatinine outside 0.5-1.4 mg/dL, then renal function (creatinine clearance or glomerular filtration rate [GFR]) > 40 mL/min/1.73 m^2
Creatinine < 1.5 mg/dl or glomerular filtration rate > 50 ml/min
Creatinine < 2 mg/dl (or a glomerular filtration rate > 60 mL/min)
Serum creatinine > 1.8 mg/dL OR glomerular filtration rate (GFR) < 30 mL/min
A serum creatinine based on age/gender, derived from the Schwartz formula for estimating glomerular filtration rate (GFR)
Within 14 days of first dose of study drug: Serum creatinine =< 1.5 x ULN or estimated glomerular filtration rate (GFR) >= 45 mL/min using the Cockcroft Gault formula
Estimated creatinine clearance of >= 60 ml/min according to the Cockcroft-Gault formula, unless calculated to be < 60 ml/min or borderline in which case glomerular filtration rate (GFR) should be formally measured, e.g. with edetic acid (EDTA) scan
Patients should have serum creatinine < 1.5 x ULN and estimated glomerular filtration rate (GFR) of > 30 mL/min. If serum creatinine is >= 1.5 x ULN, then patient must have creatinine clearance >= 51 mL/min estimated using the Cockcroft-Gault equation.
Glomerular filtration rate ? 45 ml/min based on Cockcroft-Gault equation
Patients must not be suitable for concurrent cisplatin as determined by the following:\r\n* Creatinine clearance less than 60ml/min; glomerular filtration rate (GFR) should be assessed by calculation from serum/plasma creatinine (Cockcroft-Gault formula)\r\n* Common Terminology Criteria for Adverse Events (CTCAE) grade (Gr) >= 2 hearing loss\r\n* CTCAE Gr >= 2 neuropathy
Creatinine < 2.0 mg/dl for adults or glomerular filtration rate > 50 ml/min for children
Serum creatinine =< 1.5 x ULN or estimated glomerular filtration rate (GFR) >= 45 mL/min using Cockcroft Gault formula
Creatinine within institutional normal limits or Glomerular filtration rate (GFR) > 50 mL/min/m^2 (calculated by the Cockcroft-Gault equation), calculated as follows:\r\n* For males = ((140 – age[years]) x (body weight [kg]))/((72) x (serum creatinine [mg/dL]))\r\n* For females = 0.85 x male value
Creatinine within institutional normal limits or glomerular filtration rate (GFR) > 60 mL/min/m^2 (calculated by the Cockcroft-Gault equation)
Glomerular filtration rate (GFR) greater than or equal to 40 ml/min using the Cockcroft-Gault formula or serum creatinine less than or equal to 1.5 x upper limit of normal (ULN)
Creatinine clearance estimated glomerular filtration rate (GFR) >= 30 mL/min/1.73 m^2 (Cockcroft-Gault)
Within 14 days of registration: Serum creatinine =< 1.8 mg/dL; for patients with a creatinine > 1.5 mg/dL or a history of renal dysfunction, an estimated glomerular filtration rate >= 35 mL/min/1.73 m^2 is required
Creatinine: =< 3 mg/dl OR if serum creatinine > 3 mg/dl, estimated glomerular filtration rate (GFR) > 30 mL/min/1.73 m^2
Creatinine < 2 mg/dl; glomerular filtration rate (GFR) > 50 mL/min (Cockroft and Gault formula)
Serum creatinine =< 1.5 x ULN or 24-hour clearance >= 50 mL/min or calculated glomerular filtration rate (GFR) of 60cc/ml using the formula of Cockcroft and Gault
Serum creatinine =< 1.5 mg/dL or estimated glomerular filtration rate (GFR) (by Cockcroft-Gault) >= 50 mL/min or 12 or 24 hour urine creatinine clearance >= 50 mL/min, unless renal insufficiency is due to tumoral ureteral obstruction in which case eligibility will be determined by the national principal investigator (or national co-PI or MSKCC co-PI if the national PI is unavailable) with notification of the MSKCC Institutional Review Board (IRB)
Serum creatinine ?1.5×upper limit of normal (ULN), or glomerular filtration rate >25 mL/min, as calculated with the Cockcroft-Gault formula.
Creatinine clearance estimated (est.) glomerular filtration rate (GFR) >= 30 mL/min/1.73 m^2 (Cockcroft-Gault)
Serum creatinine =< 2 mg/dL (or glomerular filtration rate >= 40 ml/min)
Serum creatinine =< 1.2 mg/dL for subjects age 18 or >; if serum creatinine is > 1.2 mg/dL, nuclear glomerular filtration rate (GFR) will be measured; GFR will need to be >= 80 ml/min/1.73 m^2 for subjects =< 40 years old; children (age < 18): nuclear GFR >= 80 mL/min/1.73 m^2
Creatinine < 2 mg/dl (or a glomerular filtration rate > 60)
Creatinine < 2 mg/dl (or a glomerular filtration rate > 60)
Serum creatinine =< 2 mg/dL (or glomerular filtration rate >= 50 ml/min as determined by the Cockcroft-Gault equation)
OR if serum creatinine > 3 mg/dL, estimated glomerular filtration rate (GFR) ? 20 mL/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) (or glomerular filtration rate [GFR] >= 60 ml/min for patients with creatinine > 1.5 x ULN)
Calculated creatinine clearance >= 60 mL/min (Cockcroft-Gault formula) or serum creatinine (Cr) less than institution ULN (the elderly will often have < 60 glomerular filtration rate [GFR])
Glomerular filtration rate (GFR) > 40 mL/minute as calculated by the Cockcroft-Gault formula
Creatinine < 2.0 x ULN or creatinine clearance (estimated [est.] glomerular filtration rate [GFR] [Cockcroft-Gault]) >= 30 mL/min
Creatinine =< 1.5 times upper limit of normal (ULN*) OR corrected glomerular filtration rate >= 70 ml/min\r\n* NOTE: *of institutional norms
Participants must have a creatinine < 3 mg/dl and a glomerular filtration rate (GFR) > 30 mL/min/1.73m^2
Serum creatinine < 2.0 mg/dl or glomerular filtration rate (GFR) > 40 mL/min/1.73m^2; patients with a creatinine > 1.2 mg/dl or a history of renal dysfunction must have glomerular filtration rate (GFR) > 40 mL/min/1.73 m^2
Serum creatinine =< 1.5 x ULN or glomerular filtration rate (GFR) of 60 cc/ml using the formula of Cockcroft and Gault
Creatinine =< 1.5 times upper limit of normal (ULN) OR glomerular filtration rate >= 70 ml/min
Serum creatinine <2.0 x upper limit of normal (ULN) or estimated glomerular filtration rate of > 50 mL/min as calculated by the Cockcroft Gault Method
Creatinine clearance (Cockcroft-Gault) greater than or equal to 30 mL/min or estimated (est) glomerular filtration rate (GFR) greater than or equal to 30 mL/min/1.73 m^2
Calculated creatinine clearance (CRCL) ?40 mL/min. Glomerular Filtration Rate (GFR) is calculated based on Cockcroft-Gault method.
Calculated creatinine clearance > 50 ml/min/1.73m^2 as calculated by the Schwartz formula for estimated glomerular filtration rate
Serum creatinine ? 1.25 x ULN; or if serum creatinine > 1.25 ULN, then calculated (Cockcroft-Gault formula, glomerular filtration rate (GFR) ? 60 mL/min;
Creatinine clearance or glomerular filtration rate greater than or equal to 50 mL/min/1.73 m^2
Pediatric Population (age <18): Calculated creatinine clearance ? 90 ml/min/1.73m2 as calculated by the Schwartz formula for estimated glomerular filtration rate (GFR)
Adult Population (age >18): Serum creatinine <1.0 mg/dL; if serum creatinine >1.0 mg/dL, then the estimated glomerular filtration rate (GFR) must be >60 mL/min/1.73 m2
Creatinine of =< 2 mg/dl and a calculated glomerular filtration rate (GFR) of > 50 mL/min/1.73 m^2
Estimated (calculated) or measured glomerular filtration rate >= 45 mL/min (or 45 mL/min/1.73 m^2); creatinine (mg/dl) used in calculation (Cockroft-Gault) must be obtained within 28 days prior to registration
CROSSOVER (STEP 2) REGISTRATION: Estimated (calculated) or measured glomerular filtration rate >= 45 mL/min (or 45 mL/min/1.73 m^2) within 28 days prior to registration; creatinine (mg/dl) used in calculation (Cockroft-Gault) must be obtained within 28 days prior to registration
Glomerular filtration rate >= 50 mL/min (calculated according to the formula of Cockcroft and Gault)
Serum creatinine < 1.5 X institutional ULN mg/dL OR glomerular filtration rate (GFR) >= 50 mL/min
creatinine ? 1.5 x upper limit of normal (ULN), or calculated glomerular filtration rate (GFR) > 50 mL/min if creatinine > 1.5x ULN
Creatinine clearance or glomerular filtration rate of >= 70 ml/min/1.73m^2
Serum creatinine < 2.0 mg/dl (provided they also have a glomerular filtration rate of at least 55 ml/min)
Serum creatinine > 1.6 mg/dL or glomerular filtration rate < 50
Glomerular filtration rate > 60ml/min; OR =< ULN creatinine per institution normals
Serum creatinine =< 1.5 mg/dL or calculated glomerular filtration rate (GFR) >= 60 mL/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) (or glomerular filtration rate >= 40 mL/min), obtained within 14 days of the first dose of study drug
Serum creatinine > 1.6 mg/dL (141 umol/L) in females and > 1.9 mg/dL (168 umol/L) in males; patients with serum creatinine values exceeding these limits are eligible for the study if their estimated glomerular filtration rates (GFR) are > 30 ml/min/1.73 m^2
Creatinine < 2.0 mg/dL, for patient with a creatinine > 1.2 mg/dL or a history of renal dysfunction an estimated glomerular filtration rate > 40 mL/min/1.73 m^2 is required
Creatinine =< 2.0 mg/dL, for patient with a creatinine > 1.2 mg/dL or a history of renal dysfunction an estimated glomerular filtration rate >= 40 mL/min/1.73 m^2 is required
Creatinine serum level >= 2 mg/dL or glomerular filtration rate (GFR) =< 30 mL/min/1.73 m^2 (contraindication for intravenous [i.v.] gadolinium only)
Creatinine > 1.8 mg/dL OR glomerular filtration rate (GFR) < 30 mL/min
Serum creatinine > 1.5 mg/dL or glomerular filtration rate < 50
Pulmonary function: a. Pulse oximetry with a baseline O2 saturation of ? 85% b. Diffusing capacity of the lung for carbon monoxide (DLCO) > 40% (corrected for hemoglobin) d. Renal function: Serum creatinine ? 1.5 x the upper limit of normal for age as per local laboratory and 24 hour urine creatinine clearance >70 mL/min; or GFR > 70 mL/min/1.73 m2 by radionuclide Glomerular Filtration Rate (GFR). e. Hepatic function:
Patients with pulmonary, cardiac, hepatic or renal impairment that would limit their ability to receive cytoreductive therapy and compromise their survival; this should include patients with any of the following:\r\n* Severe pulmonary dysfunction associated with a carbon monoxide diffusing capacity (DLCO) (corrected for hemoglobin) < 60%, or requires supplemental oxygen\r\n* Uncontrolled malignant arrhythmias, or clinical evidence of congestive heart failure (New York class III-IV) or ejection fraction < 50%\r\n* Renal disease with estimated glomerular filtration rate (GFR) by creatinine clearance or iothalamate clearance < 50 ml/min/1.73 m^2 body surface area\r\n* Serum glutamate pyruvate transaminase (SGPT)/aspartate aminotransferase (AST) > 3 times normal or direct bilirubin greater than 2.5 mg/dL on two repeated tests
Decreased renal function with a GFR of less than 50ml/1.73m2/min.
Adequate renal function as evidenced by serum creatinine ?2.0 × ULN or creatinine clearance 40 mL/min based on the Cockcroft-Gault glomerular filtration rate (GFR)
Within 7-10 days of study drug administration: Renal function\r\n* Adults (age 18 or >): Serum creatinine =< 1.2 mg/dl; if serum creatinine is > 1.2 mg/dL, nuclear glomerular filtration rate (GFR) will be measured\r\n** GFR will need to be >= 80 ml/min/1.73 m^2 for subjects =< 40 years old\r\n** >= 70 ml/min/1.73 m^2 for subjects between 41-50\r\n** >= 60 ml/min/1.73 m^2 for subjects between 51-60\r\n** >= 50 ml/min/1.73 m^2 for subjects > 60 years old\r\n* Children (age < 18): nuclear GFR >= 80 mL/min/1.73 m^2
Inadequate renal function at screening as demonstrated by creatinine clearance < 50 mL/min or glomerular filtration rate < 50 mL/min/1.73 m^2
Adequate renal function with glomerular filtration rate equal to or greater than 30 ml/min/1.73 m2
Adequate renal function defined as normal serum creatinine for the participant's age or creatinine clearance or radioisotope glomerular filtration rate (GFR) 70 milliliter per minute per 1.73 square meter (mL/min/1.73 m^2) at Cycle 1 Day 1 pre-dosing
Patients must have adequate renal/hematologic function, as defined by creatinine clearance > 30ml/min and platelets>50,000.
Adequate renal function defined by a creatinine clearance of ?30 mL/min
Adequate renal function: Estimated glomerular filtration rate ? 30 mL/minute using the Cockroft-Gault formula or: a serum creatinine based on age/gender as outlined in the protocol
Subjects must have adequate kidney function, with serum creatinine < 1.5 x upper limit of normal (ULN) or calculated glomerular filtration rate (GFR) of > 45/mL/min/1.73 m^2
Subjects must have adequate renal function as evidenced by a serum creatinine ?2.0 × ULN or creatinine clearance >40mL/min based on Cockroft-Gault glomerular filtration rate (GFR)
Patient must have adequate renal function as evidenced by: Serum creatinine ?2.0 × ULN or Creatinine clearance >40 mL/min based on the Cockroft-Gault glomerular filtration rate (GFR) estimated: (140-Age) x (weight in kg) x (0.85 if female)/72 x serum creatinine
Adequate renal function, defined as serum creatinine ?1.5x ULN or GFR >50 mL/min
Renal function\r\n* >= 70 ml/min/1.73 m^2 for subjects between 41-50\r\n* >= 60 ml/min/1.73 m^2 for subjects between 51-60\r\n* >= 50 ml/min/1.73 m^2 for subjects > 60 years old\r\n** Renal function criteria based on our previous experience with 90Y-DOTATOC therapy and known changes in GFR with age
Adequate renal function defined as glomerular filtration rate ? 40 mL/min,
Subjects must have adequate renal function as evidenced by: a. Serum creatinine ?2.0 × ULN OR b. Creatinine clearance >40 mL/min based on the Cockroft-Gault glomerular filtration rate (GFR) estimation: (140 - Age) x (weight in kg) x (0.85 if female)/72 x serum creatinine
Subjects with end stage renal function (creatinine clearance [CrCl] < 15 mL/min or glomerular filtration rate [GFR] <15 mL/min) regardless of whether hemodialysis is required
Subjects must have adequate renal function as evidenced by: • Serum creatinine ?2.0 × ULN OR • Creatinine clearance greater than 40 mL/min based on the Cockroft-Gault glomerular filtration rate (GFR) estimation: (140 - Age) x (weight in kg) x (0.85 if female)/72 x serum creatinine
Creatinine clearance > 60 ml/min/1.73 m^2; glomerular filtration rate (GFR) may also demonstrate adequate renal function
Renal Function: Patients must have serum creatinine ? 1.5 times upper limit of institutional normal for age and/or GFR ? 70 mL/min/1.73 m2.
Adequate renal function [creatinine ? 1.5x ULN (upper limit of normal)] or GFR of ? 60mL/min.
Adequate renal function (creatinine ? 1.5×ULN [upper limit of normal]) or glomerular filtration rate of ? 60 mL/min
Adequate renal function, defined as serum creatinine ?2.0 times ULN and creatinine clearance >50 mL/min or estimated glomerular filtration rate (eGFR) >50 mL/min/1.73 m^2
Adequate renal function (creatinine ? 1.5x upper limit of normal [ULN]) and/or glomerular filtration rate (GFR) of ?50 mL/min.
13. Adequate renal function (creatinine ? 1.5 x ULN [upper limit of normal] or glomerular filtration rate of ? 50mL/min).
Adequate renal function as evidenced by: serum creatinine ?2.0 × ULN; OR creatinine clearance > 40 mL/min based on the Cockroft-Gault GFR estimation: (140 - Age) x (weight in kg) x (0.85 if female)/72 x serum creatinine
Must have adequate organ function as defined by the following values: renal function - 24 hr creatinine clearance (revised Schwartz formula), or radioisotope glomerular filtration rate (GFR) >=60 milliliter (mL) per minute per 1.73 meter square (mL/min/1.73m^2); or a serum creatinine <=upper limit of normal (ULN) for age and gender; liver functions as bilirubin (sum of conjugated + unconjugated) <=1.5 x ULN for age, alanine aminotransferase (ALT) <=2.5 x ULN; for the purposes of enrollment and toxicity monitoring the ULN for ALT will be 45 unit per liter (U/L); cardiac function - corrected QT (QTcB) interval <480 milliseconds (msec), left ventricular ejection fraction (LVEF) >=lower limit of normal (LLN) by ECHO.
Adequate renal and metabolic function defined as: calculated glomerular filtration rate (eGFR) (Schwartz formula), or radioisotope GFR >=90 milliliters/minutes (mL/min)/1.73 meter square (m^2); or a serum creatinine within the institutional reference range upper limit of normal (for age/gender, if available).
Requirement for CD34+ stem cell selection for a second infusion of stem cells following an allogeneic stem cell transplant from a related or unrelated adult donor for the following conditions:\r\n* Primary graft rejection\r\n* Secondary graft rejection\r\n* Poor graft function \r\n* Disease recurrence\r\nNote: pre-infusion conditioning with chemotherapy and/or immunotherapy to be determined by the primary BMT physician and the protocol principal investigator (PI) based on clinical condition of the patient\r\n* Specific Organ System Function Requirements from PBMT 1001\r\n** Myeloablative\r\n*** Cardiac (shortening fraction of > 26% by echo or ejection fraction of > 47%)\r\n*** Renal (creatinine clearance or glomerular filtration rate [GFR] >= 40 ml/min, or > 60 ml/min.1.73 m^2)\r\n*** Pulmonary (DLCO > 50% by pulmonary function test [PFT])\r\n*** Liver (AST/ALT no greater than 3 times the upper limit of normal)\r\n** Reduced Intensity\r\n*** Cardiac (shortening fraction of > 20% by echo or ejection fraction of > 40%)\r\n*** Renal (creatinine clearance or GFR >= 30 ml/min, or > 40 ml/min 1.73 m^2)\r\n*** Pulmonary (DLCO > 40% by PFT)\r\n*** Liver (AST/ALT no greater than 5 times the upper limit of normal)
Patients with inadequate renal function (creatinine >= 1.5 times upper limit of normal) or acute or chronic renal insufficiency (glomerular filtration rate < 20 ml/min)
ALT ? 2.5 x ULN f. Estimated glomerular filtration rate of at least 50 mL/min by the Cockcroft Gault formula
Estimated glomerular filtration rate (eGFR) (using Cockcroft & Gault equation) > 45 mL/min, within 14 days of registration
End-stage renal disease (estimated glomerular filtration rate [GFR] < 55 ml/min/body surface area [BSA]), unless the estimated creatinine clearance by Cockcroft Gault is >= 55 ml/min prior to randomization
estimated creatinine clearance (CrCl, by Cockcroft-Gault formula) or estimated glomerular filtration rate (eGFR) ? 30 mL/min/1.73 m2
Subject has any of following laboratory abnormalities: WBC < 3000/uL; ANC < 1500/uL; Hemoglobin < 8 g/dL; Estimated glomerular filtration rate < 30 mL/min/1.73 m2; ALT > 3 x ULN ; Bilirubin > 1.5 x ULN
Estimated glomerular filtration rate (EGFR) >= 30 ml/min
Serum creatinine ?2.0 mg/dL or eGFR (estimated Glomerular Filtration Rate) < 40 mL/min.
Estimated glomerular filtration rate (eGFR) of > 45 mls/min using Cockcroft and Gault formula
Creatinine =< 1.5 X ULN and estimated glomerular filtration rate (GFR) (eGFR) >= 60 ml/min
Glomerular filtration rate (either estimated or calculated from 24-hour urine collection) ? 45 mL/min
Estimated glomerular filtration rate (eGFR) >= 50 mL/min/1.73m^2 per current institutional calculation formula (within 14 days of study registration)
Estimated glomerular filtration rate (eGFR) >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal OR
Patients will not be eligible if they present with moderate to severe decrease in creatinine clearance (estimated glomerular filtration rate [eGFR] < 45 mL/min/1.73m2)
Estimated glomerular filtration rate (eGFR) > 45 mL/min/1.73 m^2
Creatinine < 1.5 mg/dl OR estimated glomerular filtration rate (eGFR) (creatinine clearance) >= 60 mL/min/1.73 m^2
Estimated glomerular filtration rate (eGFR) >= 50 mL/min/1.73m^2 per current institutional calculation formula
Patients with estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73 m^2
Estimated glomerular filtration rate (eGFR) >= 60 mL/min/1.73 m^2
Severe renal dysfunction (estimated glomerular filtration rate at the Screening visit; calculated by the central laboratory) <30 mL/min/1.73 m^2 or on chronic dialysis
Estimated glomerular filtration rate (eGFR) of at least 50 ml/min; the Cockcroft Gault formula will be utilized to determine eGFR when blood urea nitrogen (BUN) and creatinine testing are performed at baseline. The combination of eGFR serum creatinine and BUN will be used to evaluate patient's renal function for safety assurance.
Estimated glomerular filtration rate (eGFR) of at least 50ml/min using the Cockcroft Gault formula will be determined at base line when testing of BUN and creatinine is performed. The combination of eGFR serum creatinine and BUN will be used to evaluate renal function and assure the safety of this patient function.
Kidney: estimated glomerular filtration rate (Cockcroft-Gault) ? 50 mL/min.
Within 14 days prior to registration: Serum creatinine < 1.5 X institutional ULN mg/dL OR estimated glomerular filtration rate (eGFR) >= 50 mL/min
Estimated glomerular filtration rate (eGFR) of at least 50 mL/min
Creatinine =< 1.5 X institutional upper limit of normal or estimated glomerular filtration rate < 45 mL/min/1.73 m^2
Either serum creatinine ? 1.5 x ULN or estimated glomerular filtration rate ? 45 mL/min/1.73 m^2
Estimated glomerular filtration rate (eGFR) > 40 mL per 1.73 m*2
Screening laboratory analyses shows any of the following abnormal laboratory results: Estimated Glomerular filtration (eGFR) rate < 30 mL/min
Estimated glomerular filtration rate (GFR) (eGFR) >= 60 ml/min
Serum creatinine ?1.5 mg/dL or estimated glomerular filtration rate (eGFR) ?60 mL/min/1.73 m2
Renal impairment defined as estimated glomerular filtration rate (EGFR) < 30
Estimated glomerular filtration rate (eGFR) greater than or equal to 60 ml/min/1.73 m^2
Estimated Glomerular Filtration Rate (eGFR) ? 60 mL/min/1.73 m2
Renal function estimated glomerular filtration rate (eGFR) > 30 mL/min via calculated creatinine clearance
Estimated glomerular filtration rate (eGFR) >= 50 ml/min/1.73m^2 using the CKD-EPI equation
Creatinine clearance >= 50 mL/min/1.73 m^2 (calculated by estimated glomerular filtration rate [eGFR] from EPIC)
Estimated glomerular filtration rate (eGFR) of at least 50 mL/min
Patients with >= grade 3 chronic kidney disease at enrollment (estimated glomerular filtration rate [eGFR] or creatinine clearance [CrCl] < 30 ml/min/1.73m^2)
All patients must be able to undergo MRI with and without contrast with a glomerular filtration rate (eGFR) greater than or equal to 30 mg/min/1.72 m^2
Serum creatinine ? 2.0 x upper limit of normal (ULN) or an estimated glomerular filtration rate (eGFR) of > 50 mL/min as calculated by the Cockcroft Gault Method
Patients will have an estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73 m^2
Estimated glomerular filtration rate ?30 mL/minute
Creatinine within normal limits for the laboratory OR creatinine clearance >= 60 mL/min/1.73 m^2 (estimated glomerular filtration rate [eGFR]) for patients with creatinine levels above the ULN for the laboratory
Cisplatin ineligibility based on one or more of the following criteria:\r\n* Estimated glomerular filtration rate (eGFR) 30-59 ml/min/1.73^2\r\n* >= Grade 2 sensory neuropathy\r\n* >= Grade 2 hearing loss
Estimated glomerular filtration rate (eGFR) < 60 within 6 weeks prior to registration
Serum creatinine ? 1.5 x upper limit of normal (ULN) or, if serum creatinine > 1.5 x ULN, estimated glomerular filtration rate (eGFR) ? 30 mL/min
Does the subject have an estimated glomerular filtration rate of at least 50 mL/min (inclusive) by the Cockcroft-Gault formula?
Heart: presence of mean left ventricular wall thickness on echocardiogram greater than 12 mm in the absence of hypertension or valvular heart disease, or unexplained low voltage (< 0.5 mV) on ECG, or NT-proBNP > 332 ng/L in the absence of impaired renal function [estimated glomerular filtration rate (eGFR) < 45 mL/min]
Estimated creatinine clearance (CrCl) or estimated glomerular filtration rate (eGFR) ? 30 mL/min/1.73 m2
Calculated creatinine clearance (estimated glomerular filtration rate [eGFR]) > 50 ml/min
Estimated Glomerular Filtration Rate <45 mL/min.
estimated glomerular filtration rate > 50 mL/min
Estimated glomerular filtration rate (eGFR) of > 50 ml/min as calculated by the Cockcroft-Gault Method
Unless felt due to underlying disease and approved by the overall principal investigator (PI): Creatinine < 2.0 mg/dl, and estimated glomerular filtration rate (eGFR) >= 60 mL/min
Subjects with severe renal failure or end stage renal disease (estimated GFR [glomerular filtration rate] of < 30 mL/min) as estimated by the Cockcroft-Gault formula
Estimated glomerular filtration rate (eGFR) < 60 within 6 weeks prior to registration
Estimated glomerular filtration rate (eGFR) >= 60 mL/min/1.73m^2, as evidenced in laboratory values =< 3 months old
Contraindication to contrast CMR including estimated glomerular filtration rate (eGFR) < 30 mls/min/1.73 m^2
Estimated glomerular filtration rate (eGFR) >= 45 mL/min
Have significant renal disease or dysfunction defined as estimated glomerular filtration rate (eGFR) < 45
Patient must have adequate bone marrow, coagulation, renal, and hepatic function; estimated glomerular filtration rate (eGFR) calculation >= 60 mL/min/1.73 m^2 (within 28 days of screening CT submission)
Severe renal insufficiency, estimated glomerular filtration rate (EGFR) < 30
Adequate renal function to tolerate intravenous gadolinium contrast injection (estimated glomerular filtration rate >= 45 mL/min/1.73 m^2 prior to initial DCE-MRI and estimated glomerular filtration rate >= 30 mL/min/1.73 m^2 for subsequent DCE-MRI scans)
Contraindications to receiving intravenous gadolinium contrast injection including prior allergic reaction and/or chronic renal insufficiency (estimated glomerular filtration rate < 45 mL/min/1.73 m^2 prior to initial DCE-MRI and estimated glomerular filtration rate < 30 mL/min/1.73 m^2 for subsequent DCE-MRI scans)
Subject has impaired renal function (estimated glomerular filtration rate [eGFR]< 30 mL/min)
Renal dysfunction with estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m^2
Abnormal renal function with estimated glomerular filtration rate (eGFR) less than 30 mL/min/m^2 based on creatinine obtained within last 30 days
Severe renal function impairment (estimated glomerular filtration rate [eGFR] < 45 mL/min/1.73 m^2) would make the patient inappropriate for enrollment due to the increased risk of nephrogenic systemic fibrosis (NSF) with higher dose of IV gadolinium-based contrast agents (GBCA) administration
Subjects with estimated glomerular filtration rate (eGFR) =< 30 mL/min/1.73 m^2 will not participate in the gadolinium (Gd) contrast-enhanced MRI
Patients with estimated glomerular filtration rate (eGFR) < 30 are not eligible
Patients with renal function (estimated glomerular filtration rate [eGFR] >= 30)
Late stage renal failure with estimated glomerular filtration rate (eGFR) of less than 30 mL/min/1.73 m^2 based on patient's serum creatinine; (‘past’ 3 months timeframe will be used to calculate the eGFR)
Estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73m^2
Patients must have an estimated glomerular filtration rate of >= 30 mL/min/1.73m^2 within six weeks of the MRI to be included in the study
Subjects with an estimated glomerular filtration rate of < 30 mL/min/1.73m^2 within six weeks of the MRI
Acute or chronic severe renal insufficiency (estimated glomerular filtration rate < 30 mL/min/1.73m^2)
Patient with significant renal insufficiency, i.e. an estimated glomerular filtration rate (eGRF) less than 30 mL/min/1.73m^2
Patient must not have an estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m^2
Estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73 m^2
Impaired renal function (chronic kidney disease [CKD] 4 or 5: estimated glomerular filtration rate [eGFR] < 30 mLs/min), which is a contraindication to gadolinium containing contrast
Estimated glomerular filtration rate (eGFR) < 30 mL/min
Estimated glomerular filtration rate < 30 mL/min
Subject presenting with acute or chronic Grade III (at least) renal insufficiency, defined as an estimated Glomerular Filtration Rate (eGFR) <60 mL/min/1.73m² based on two eGFR assessments, one within 7 days before the first study MRI and on the day of the MRI (if any of the eGFR result is <60 mL/min/1.73m², the subject is not eligible).
Contraindication to MRI (e.g. claustrophobia, pacemaker, estimated glomerular filtration rate ? 50mls/min)
Serum creatinine within 3 weeks prior to Eovist MRI =< 1.8 mg/dl and estimated glomerular filtration rate (eGFR) must be > 30 ml/min/1.73 m^2
Estimated glomerular filtration rate (eGFR) >= GFR 70 mL/min/1.73 m^2
Estimated glomerular filtration rate (eGFR) > 60 mL/min/1.73 m^2 or estimated creatinine clearance (eCrCL) > 60 mL/min
Have an estimated glomerular filtration rate (eGFR) (using the Cockcroft-Gault equation) of more than 60 mL/min
Calculated creatinine clearance or radioisotope glomerular filtration rate < 70 mL/min/1.73 m^2
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 OR
Measured creatinine clearance > 70 ml/min/1.73 m^2 or normal radioisotope glomerular filtration rate (GFR)
Creatinine clearance or radioisotope Glomerular Filtration Rate ? 70millileters/minute/1.73 meters2 or a normal serum creatinine based on age/gender
Serum creatinine =< 1.5x ULN for age OR a creatinine clearance or radioisotope GFR >= 70ml/min/1.73 m^2
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or
Glomerular filtration rate (GFR), calculated via I-125 iothalamate clearance, 24-hour creatinine clearance, or Schwartz formula, >= 70 mL/min or >= 50 mL/min/1.73 m^2 done within 4 weeks prior to study entry
TREATMENT WITH SJCAR19: Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 50 ml/min/1.73 m^2 (GFR >= 40 ml/min/1.73 m^2 if < 2 years of age)
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70mL/min/1.73 m^2.
Serum creatinine =< 1.5 x upper limit of normal (ULN) for age; if the serum creatinine is above these values, the calculated creatinine clearance or radioisotope glomerular filtration rate (GFR) must be >= 70 mL/min/1.73 m^2
Serum creatinine =< 1.5 x the upper limit of normal for age as per local laboratory and 24 hour urine creatinine clearance > 70 mL/min/1.73 m^2 OR glomerular filtration rate (GFR) > 70 mL/min/1.73 m^2 by radionuclide GFR
Subject has adequate renal function defined as: Adequate real function with Sserum creatinine based on age/gender calculated using the Schwartz formula as described in protocol, or a 24-hour creatinine clearance or radioisotope glomerular filtration rate (GFR) (radioisotope or iothalamate) ? 70 mL/min/1.73 m2.
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 60 ml/min/1.73 m^2, OR
Maximum serum creatinine 1.5 mg/dL OR a creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70ml/min/1.73 m^2
Creatinine greater than > 2 x ULN for age or creatinine clearance/glomerular filtration rate (GFR) < 40 ml/min/1.73 m^2
Creatinine clearance or glomerular filtration rate (GFR) > 60 mL/min/1.73 m^2; if a creatinine clearance is performed at end induction and the result is < 100 ml/min/1.73 m^2, a GFR must then be performed using a nuclear blood sampling method or iothalamate clearance method; camera method is NOT allowed as measure of GFR prior to or during consolidation therapy for patients with GFR or creatinine clearance of < 100 ml/min/1.73 m^2
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 60 ml/min/1.73m^2
Serum creatinine concentration =< 3 x the institutional upper limit of normal (ULN) or creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2
Serum creatinine based on age or creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/ml/min/1.73 m^2
Creatinine clearance or radioisotope GFR ? 70ml/min/1.73 m² OR age/gender appropriate serum creatinine.
ELIGIBILITY CRITERIA FOR T-CELL PRODUCT INFUSION: Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or a normal serum creatinine based on age/gender
Serum creatinine > 1.5 x the upper limit of normal for age, or calculated creatinine clearance or nuclear glomerular filtration rate (GFR) < 70 ml/min/1.73 m^2
Creatinine clearance or radioisotope glomerular filtration rate (GFR) > 70 ml/min/1.73 m^2 or normal serum creatinine for patient’s age and gender
Serum creatinine =< 1.5 x upper limit of normal (ULN) for age or creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2
Serum Creatinine <~ 1.5 x normal, or creatinine clearance of 70 ml/min/1.73 m^2 or an equivalent glomerular filtration rate (GFR) as determined by the institutional normal range
Creatinine clearance or radioisotope GFR 70ml/min/1.73 m^2 or
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or
Serum creatinine =< 1.5 x upper limit of normal or a creatinine clearance or glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or
Patients with severe renal disease (i.e. measured or estimated creatinine clearance or radioisotope glomerular filtration rate [GFR] =< 70 ml/min/1.73 m^2)
Creatinine clearance or radioisotope glomerular filtration rate >= 60 mL/min
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or
Creatinine clearance calculated using the Schwartz formula, or radioisotope glomerular filtration rate (GFR) > 70 mL/min/1.73 m2.
Renal function defined as (Calculated creatinine clearance or radioisotope Glomerular Filtration Rate (GFR) > 60 mL/min/1.73 m2 OR serum creatinine based on age/gender
Creatinine clearance or radioisotope GFR ? 70mL/min/1.73m2 or serum creatinine based on age/gender.
Creatinine clearance or estimated radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or
Creatinine =< 1.5 times ULN for age OR a creatinine clearance or glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2; obtained =< 7 days prior to registration
Maximum serum creatinine 1.5 mg/dL OR a creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2
Subjects must have a serum creatinine level that is ? 1.5 × institutional upper limit of normal (ULN) according to age. If serum creatinine level is > 1.5 × ULN, the subject must have a calculated creatinine clearance or radioisotope glomerular filtration rate (GFR) ? 70 mL/min/1.73 m2.
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 OR
Serum creatinine =< upper limit of normal (ULN) for age; if serum creatinine above these values, the calculated creatinine clearance or radioisotope glomerular filtration rate (GFR) must be >= 60 ml/min/1.73 m^2
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2
Patient must have a calculated creatinine clearance or radioisotope GFR > 60mL/min/1.73m2 or a normal serum creatinine based on age/gender
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2
Serum creatinine =< 1.5 x institutional upper limit of normal (ULN) for age; if the serum creatinine is above these values, the calculated creatinine clearance or radioisotope glomerular filtration rate (GFR) must be >= 60 mL/min/1.73m^2
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 100 ml/min/1.73 m^2
Creatinine clearance or radioisotope GFR >= 60 ml/min/1.73 m^2
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 30 mL/min/1.73 m^2
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 OR