Participants who have hepatitis C (both reactive anti-hepatitis C virus [HCV] antibody and detectable HCV RNA) and hepatitis B (hepatitis B surface antigen [HBsAg] positive and anti-hepatitis B core [HBc]-total positive), may be enrolled, provided total bilirubin is =< . x institutional ULN, and AST (SGOT) and ALT (SGPT) must be =<  X institutional upper limit of normal, and hepatitis B virus (HBV) deoxyribonucleic acid (DNA) <  IU/mL (if hepatitis B positive) within  weeks prior to enrollment
Negative for hepatitis B, or if infected with hepatitis B, receiving anti-hepatitis B therapy; all participants will be required to be screened for hepatitis B; per Infectious Disease Society of America (IDSA) and Assistance for AIDS Specific Drugs (AASD) guidelines, those participants that show no immunity, defined by the lack of hepatitis B surface antigen antibody, and show evidence of chronic infection (i.e. hepatitis B surface antigen [HBsAg]+, hepatitis B core [HBcore]+, hepatitis B surface antibody [HBsAB]-) will be required to be on anti-hepatitis B therapy during the study in order to be eligible; patients will be permitted to enroll in the study provided normal liver function tests and no evidence of cirrhosis; the exact hepatitis B therapy will be at the discretion of the infection disease specialist or investigator; however all patients who present with acute hepatitis B or show normal transaminases and are hepatitis B virus HBsAg surface protein antigen (HBsAg) positive (+) and immunoglobulin M (IgM)+ for hepatitis core antigen will not be eligible for trial enrollment
Patients with known hepatitis B surface antigen seropositive or known or suspected active hepatitis C infection are not eligible; NOTE: patients who have isolated positive hepatitis B core antibody (i.e., in the setting of negative hepatitis B surface antigen and negative hepatitis B surface antibody) must have an undetectable hepatitis B viral load; patients who have positive hepatitis C antibody may be included if they have an undetectable hepatitis C viral load
Has known active hepatitis B (e.g., hepatitis B virus surface antigen [HBsAg] reactive) or hepatitis C (e.g., hepatitis C antibody [Hep C Ab] is detected)
For selected higher-risk group B and all group C participants receiving rituximab only (e.g., those with MLBCL, stage III with LDH >=  x ULN, and/or bone marrow/central nervous system [CNS] involvement): all participants who will receive rituximab must have hepatitis screening prior to enrollment; participants whose results indicate that they are carrier of hepatitis B can still be treated as per group B or C but will NOT receive rituximab; this screening must be done for eligibility for participants who will receive rituximab, BUT the results are not needed prior to enrollment:\r\n* Hepatitis B immunization status (vaccination yes or no)\r\n* Hepatitis B surface antigen (HBsAg)\r\n* Anti-hepatitis B surface (HBs) antibody\r\n* Anti-hepatitis B core (HBc) antibody
Known hepatitis B surface antigen seropositivity or known or suspected active hepatitis C infection; Note: Patients who have isolated positive hepatitis B core antibody (i.e. in the setting of negative hepatitis B surface antigen and negative hepatitis B surface antibody) must have an undetectable hepatitis B viral load
Positive for Hepatitis B surface antigen.
Active hepatitis B infection as demonstrated by test for hepatitis B surface antigen. Subjects who are hepatitis B surface antigen negative but are hepatitis B core antibody positive must have undetectable hepatitis B DNA and receive prophylaxis against viral reactivation. Prophylaxis should be initiated prior to lymphodepleting therapy and continued for  months.
No known positivity of hepatitis B surface antigen (HBsAg), or of positive hepatitis C antibody
Negative hepatitis B surface antigen (HBsAg) test at screening
The participant is positive for hepatitis B surface antigen, or hepatitis C ribonucleic acid (RNA)
Subject has known positivity for Hepatitis B surface antigen or Hepatitis C antibody
Participants who are hepatitis C virus antibody positive, or hepatitis B virus surface antigen positive must be free of clinical evidence of cirrhosis as determined by the principal investigator in consultation with the gastroenterology service; timeline: within  weeks prior to enrollment
Hepatitis B surface antigen (HBsAg) positivity without active treatment; a subject found to be HBsAg positive should be on antiviral therapy for at least two weeks prior to study registration
Known history of or is positive for hepatitis B (hepatitis B surface antigen reactive) or known active hepatitis C (hepatitis C virus RNA or hepatitis C antibody is detected)
Child-Pugh B or C hepatic impairment; patients with a history of hepatitis or significant exposure risk should be tested for hepatitis B and C with serologic markers: hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (HBs Ab), hepatitis B core immunoglobulin G antibody (HBcoreIgG Ab), hepatitis C virus antibody (HCV Ab); patients with active hepatitis B or C are excluded
Positive serology for hepatitis B (HB) defined as a positive test for hepatitis B surface antigen or hepatitis B core antibody
Known hepatitis B surface antigen (HBsAg) positive.
Active hepatitis B or hepatitis C (defined as positive-HBV surface antigen or detectable HCV-antibody); patients with a positive Hepatitis B core antibody (HBVcAb) must have negative viral load measurement
Presence of positive test results for hepatitis B surface antigen (HBsAg) or hepatitis C antibodies (HcAb) (for participants receiving regimen including rituximab)
Acute or active hepatitis B or hepatitis C infection. Patients with anti-hepatitis B core antigen (HBc) positive, or hepatitis B surface antigen (HBsAg) but viral deoxyribonucleic acid (DNA) negative are exception(s).
Active systemic infection requiring therapy, positive tests for hepatitis B surface antigen or hepatitis C ribonucleic acid (RNA)
Hepatitis B - antigen positive
Hepatitis B surface antigen (HBsAg) and hepatitis C virus antibody (HCVAb) blood test must be done at screening for all patients; patients who test positive for hepatitis C antibodies or the hepatitis B antigen are ineligible
The participant is positive for hepatitis B surface antigen, or hepatitis C ribonucleic acid (RNA)
Has untreated active hepatitis B (e.g., hepatitis B surface antigen [HBsAg] reactive)
Positive exclusion tests: urine pregnancy tests (if applicable), HIV, hepatitis B surface antigen, or hepatitis C virus
Hepatitis B surface antigen (HBsAG) positive or hepatitis B core antibody positive
Patients who have a known active hepatitis B or hepatitis C infection are ineligible; patient must have documented evidence of negative tests for the presence of hepatitis B surface antigen and hepatitis C (anti-hepatitis C virus [HCV] antibody OR hepatitis [Hep] C RNA-qualitative); human immunodeficiency virus (HIV)-positive patients are eligible if the following criteria are met:\r\n* Stable on their antiretroviral agents\r\n* Have CD counts above \r\n* Undetectable viral loads, and\r\n* No need for prophylactic medications for an opportunistic infections
EXCLUSION CRITERIA FOR STRATUM C: Patients who have a known active hepatitis B or hepatitis C infection are ineligible; patient must have documented evidence of negative tests for the presence of hepatitis B surface antigen and hepatitis C (anti-HCV antibody OR Hep C RNA-qualitative); HIV-positive patients are eligible if the following criteria are met:\r\n* Stable on their antiretroviral agents\r\n* Have CD counts above \r\n* Undetectable viral loads, and\r\n* No need for prophylactic medications for an opportunistic infections
Known active hepatitis B (e.g., hepatitis B surface antigen [HBsAg] reactive) or hepatitis C (e.g., hepatitis C virus [HCV] ribonucleic acid [RNA] [qualitative] is detected); NOTE: patients with active hepatitis B defined by hepatitis B surface antigen positivity or core antibody positivity in the presence of hepatitis B deoxyribonucleic acid (DNA) are not eligible for this study; patients with a positive hepatitis B core antibody but with negative hepatitis B DNA may participate, but must have hepatitis serologies and hepatitis B DNA monitored periodically by the treating physician\r\n* NOTE: intravenous immunoglobulin (IVIG) can cause a false positive hepatitis B serology; if patients receiving routine IVIG have core antibody or surface antigen positivity without evidence of active viremia (negative hepatitis B DNA) they may still participate in the study, but should have hepatitis serologies and hepatitis B DNA monitored periodically by the treating physician
Active hepatitis B (defined as having a positive hepatitis B surface antigen [HBsAg] or positive hepatitis B virus [HBV] deoxyribonucleic acid [DNA] test at screening) or hepatitis C
Hepatitis B surface antigen or hepatitis B core antibody positive
Active hepatitis B virus (HBV) or hepatitis C virus infection that requires treatment or at risk for HBV reactivation. At risk for HBV reactivation is defined as hepatitis B surface antigen positive or anti-hepatitis B core antibody positive. Previous test results obtained as part of standard of care (ie, hepatitis B surface antigen negative, surface antibody positive) may be used for purposes of eligibility and tests do not need to be repeated. Subjects with previous positive serology results must have negative polymerase chain reaction results. Subjects whose immune status is unknown or uncertain must have results confirming immune status before enrollment
Subject is known to be positive for hepatitis B or C infection with the exception of those with an undetectable viral load; hepatitis B or C testing is not required and subjects with serologic evidence of prior vaccination to hepatitis B virus (HBV) (i.e., hepatitis B surface antigen [HBsAg], hepatitis B surface antibody positive (anti-HBs+) and antibody to hepatitis B core antigen [anti-HBc]) may participate
History of human immunodeficiency virus (HIV) infection or active hepatitis B or C; intravenous immunoglobulin (IVIG) can cause a false positive hepatitis B serology; if patients receiving routine IVIG have core antibody or surface antigen positivity without evidence of active viremia (negative hepatitis B deoxyribonucleic acid [DNA]) they may still participate in the study, but should have hepatitis serologies and hepatitis B DNA monitored periodically by the treating physician
Known history of hepatitis B or hepatitis C infection or known positive test for hepatitis B surface antigen, hepatitis B core antigen, or hepatitis C polymerase chain reaction
Positive hepatitis panel (including hepatitis B surface antigen and/or hepatitis C virus antibody) prior to or at Screening
Known hepatitis B surface antigen seropositive or known or suspected active hepatitis C infection\r\n* Note: patients who have isolated positive hepatitis B core antibody (ie, in the setting of negative hepatitis B surface antigen and negative hepatitis B surface antibody) must have an undetectable hepatitis B viral load
Has known hepatitis B surface antigen seropositive, or known or suspected active hepatitis C infection. Note: Participants who have isolated positive hepatitis B core antibody (i.e., in the setting of negative hepatitis B surface antigen and negative hepatitis B surface antibody) must have an undetectable hepatitis B viral load.
Hepatitis B virus surface antigen positive
Patients who are human immunodeficiency virus (HIV) positive but who have no prior acquired immunodeficiency syndrome (AIDS)-defining illness and have CD cells of at least /mm^ are eligible; HIV-positive patients must not have multi-drug resistant HIV infection or other concurrent AIDS-defining conditions; patients must not be sero-positive for hepatitis B (hepatitis B surface antigen positive or anti-hepatitis B core antigen positive) or seropositive for hepatitis C (anti-hepatitis C antibody positive); however, patients who are immune to hepatitis B (anti-Hepatitis B surface antibody positive) are eligible (e.g. patients immunized against hepatitis B)
Serologic evidence of current or past hepatitis B infection based on the results of testing for hepatitis B virus surface antigen (HBsAg) and anti-hepatitis B virus core (HBc)  patients positive for HBsAg or hepatitis B virus core antibody (HBcAb) are excluded
No active or chronic hepatitis infection; hepatitis C virus (HCV) antibody (for hepatitis C) and hepatitis B Surface antigen must be negative within  days prior to Step  registration
Negative for hepatitis B surface antigen; positive hepatitis B tests can be further evaluated by confirmatory tests; and if confirmatory tests are negative, the patient can be enrolled; patients with a known history of hepatitis B are not eligible
Documented virology status of hepatitis, as confirmed by screening anti-hepatitis B surface antigen (HBsAg), anti-hepatitis B virus core antibody (HBc), and/or anti-hepatitis C virus (HCV)
All participants will be required to be screened for hepatitis B; all participants who present with acute hepatitis B or show normal transaminases and are hepatitis B surface antigen (HBsAg) positive (+) and IgM+ for hepatitis core antigen will not be eligible for trial enrollment; per Infectious Diseases Society of America (IDSA) and Assistance for AIDS Specific Drugs (AASD) guidelines, those participants that show no immunity, defined by the lack of hepatitis B surface antibody, and show evidence of chronic infection (i.e. hepatitis B [HB]sAg+, HBcore+, hepatitis B surface antibody [HBsAB] negative [-]) will be required to be on anti-hepatitis B therapy, during the study, in order to be eligible; the exact hepatitis B therapy will be at the discretion of the infection disease specialist or investigator; if infected with hepatitis B, participants will be permitted to enroll in the study provided liver function tests meet criteria listed above, there is no evidence of cirrhosis AND participants will be required to be on anti-hepatitis B therapy
Chronic hepatitis: Positive test for Hepatitis B virus surface antigen or Hepatitis C antibody (except for subjects with hepatocellular carcinoma)
Known active or chronic hepatitis B infection (defined as having a positive hepatitis B surface antigen [HBsAg] test at screening); subject with past or resolved hepatitis B infection (defined as having a negative HBsAg test and positive antibody to hepatitis B core antigen test) are eligible; hepatitis B viral deoxyribonucleic acid (DNA) must be obtained in subjects with positive hepatitis B core antibody prior to first treatment start
Known hepatitis B surface antigen seropositive or known or suspected active hepatitis C infection; Note: Patients who have isolated positive hepatitis B core antibody (ie, in the setting of negative hepatitis B surface antigen and negative hepatitis B surface antibody) must have an undetectable hepatitis B viral load; patients who have positive hepatitic C antibody may be included if they have an undetectable hepatitis C viral load
Active infection requiring therapy, including positive tests for hepatitis B surface antigen or hepatitis C ribonucleic acid (RNA)
Patients with history of hepatitis B or C infection are not permitted to enroll; to enroll patients must have no evidence of hepatitis B or C surface antigen (Ag) and negative hepatitis B core antibody (Ab); patients previously immunized for hepatitis B who are hepatitis B surface Ab positive, but surface Ag and core Ab negative are eligible
Active infection requiring therapy, positive tests for hepatitis B surface antigen or hepatitis C ribonucleic acid (RNA)
Positive serological test for hepatitis B surface antigen (HBsAg), hepatitis B core antibody (HBcAb) or hepatitis C serology.
Active hepatitis B infection (defined as the presence of detectable hepatitis B virus [HBV] deoxyribonucleic acid [DNA], hepatitis B e [HBe] antigen or hepatitis B surface [HBs] antigen); subjects with serologic evidence of prior vaccination (hepatitis B surface antigen [HBsAg] negative, anti-HBs antibody positive, anti-hepatitis B core [HBc] antibody negative) are eligible; patients who are HBsAg negative/hepatitis B surface antibody (HBsAb) positive but hepatitis B core antibody (HBcAb) positive are eligible, provided HBV DNA is negative
Active infection requiring therapy, positive tests for hepatitis B surface antigen or hepatitis C ribonucleic acid (RNA)
Positive tests for hepatitis B surface antigen or hepatitis C ribonucleic acid (RNA)
Participants who are Hepatitis B surface antigen positive (HBsAg+) (must be PCR negative) who are taking antivirals, are allowed to enroll.
Active Hepatitis A, B, or C infection or known to be positive for HCV RNA or HBV surface antigen. Patients who have been vaccinated against Hepatitis B and who are positive for ONLY the Hepatitis B surface antibody are permitted to participate in the study.
Active hepatitis B as defined by seropositivity for hepatitis B surface antigen (HBsAg); subjects with positive hepatitis B core antibody titers and normal liver transaminases are allowed provided that antiviral prophylaxis is administered per institutional guidelines; NOTE: subjects with hepatitis C antibody will be eligible provided that they do not have elevated liver transaminases or other evidence of active hepatitis
History of acute/chronic hepatitis B or C and/or carriers of hepatitis B or C (positive for hepatitis B surface antigen or positive anti-hepatitis C antibody test) and evidence of current or active infection (e.g. HCV RNA test)
Hepatitis B surface antigen (+) or hepatitis C positive in preceding six months
Patients who are hepatitis B core antibody positive and or have positive hepatitis B surface antigen will require hepatology consultation; the risk/benefit profile of transplant and hepatitis B will be discussed with the patient and eligibility determined by the PI or the LAI
Hepatitis B surface antigen positive
Active hepatitis B or C viral infection or hepatitis B surface antigen positive
Active systemic infection requiring therapy, positive tests for hepatitis B surface antigen or hepatitis C antibody
RECIPIENT: Chronic active hepatitis B; patient may be hepatitis B core antibody positive; for patients with a concomitant positive hepatitis B surface antigen, patients will require a hepatology consultation; the risk-benefit profile of transplant and hepatitis B will be discussed with the patient, and eligibility determined by the PI or lead associate investigator
Hepatitis B surface antigen negative and hepatitis C antibody negative
No active hepatitis B or C (if hepatitis B surface antigen positive [HBsAg+] or hepatitis C virus antibody positive [HCV ab+], viral load must be undetectable), and if serologies are positive, MUST HAVE hepatology clearance for ASCT
Active hepatitis B or C viral infection or hepatitis B surface antigen positive
Patients with brain metastases or presence of other intracranial lesions at risk for bleeding by history or baseline radiologic imaging. Active infection, including Hepatitis B and Hepatitis C infection. Patients with anti-hepatitis B core antibody (HBc) positive, or hepatitis B surface antigen (HBsAg) but DNA negative are exception(s).
Chronic active hepatitis B; patient may be hepatitis B core antibody positive; for patients with a concomitant positive hepatitis B surface antigen, patients will require a hepatology consultation; the risk-benefit profile of transplant and hepatitis B will be discussed with the patient, and eligibility determined by the PI and the protocol chairperson
Evidence of infection with HIV, hepatitis B or hepatitis C; patients must be HIV negative, hepatitis B surface antigen, and hepatitis C antibody negative; the high degree of immune suppression that may be used in this study may lead to the activation or progression of these viral illnesses
Presence of Hepatitis B surface antigen (HBsAg) at screening or within  months prior to first dose of study treatment.
Positive hepatitis panel (including hepatitis B surface antigen and/or hepatitis C virus antibody) prior to or at Screening
Positive test result for hepatitis B surface antigen (HBsAG), hepatitis B core antibody (HBcAb), or confirmed positive anti-HIV antibody test
Positive hepatitis panel (including hepatitis B surface antigen and/or hepatitis C virus antibody) prior to or at Screening
Known hepatitis B surface antigen seropositivity or known or suspected active hepatitis C infection\r\n* Note: Patients who have isolated positive hepatitis B core antibody (i.e., in the setting of negative hepatitis B surface antigen and negative hepatitis B surface antibody) must have an undetectable hepatitis B viral load; patients who have positive hepatitis C antibody may be included if they have an undetectable hepatitis C viral load
Known Hepatitis B surface antigen positive or hepatitis C positive
Presence of hepatitis B surface antigen (HBsAg), or hepatitis B core antibody (HBcAb at screening or within  months prior to first dose of study treatment.
Presence of hepatitis B surface antigen (HBsAg), or hepatitis B core antibody (HBcAb at Screening or within  months prior to first dose of study treatment).
REGISTRATION TO TREATMENT (STEP ): Patient must not have a known history of hepatitis B (defined as hepatitis B surface antigen [HBsAg] reactive)
REGISTRATION TO TREATMENT (STEP ): Patients must not have a known history of hepatitis B (defined as hepatitis B surface antigen [HBsAg] reactive)
Known hepatitis B surface antigen seropositive or known or suspected active hepatitis C\r\nInfection; Note: Patients who have isolated positive hepatitis B core antibody (i.e., in the setting of negative hepatitis B surface antigen and negative hepatitis B surface antibody) must have an undetectable hepatitis B viral load
Negative hepatitis B surface antigen
Presence of hepatitis B surface antigen (HBsAg) or positive hepatitis C antibody test result at screening. Subjects with positive hepatitis C antibody due to prior resolved disease can be enrolled only if a confirmatory negative hepatitis C ribonucleic acid polymerase chain reaction is obtained.
Subject has know positivity for Hepatitis B surface antigen test or Hepatitis C Antibody
Hepatitis B surface antigen positive
Known history of Human Immunodeficiency Virus (HIV) or active Hepatitis B or C. Intravenous immunoglobulin (IVIG) can cause a false positive hepatitis B serology. If patients receiving routine IVIG have core antibody or surface antigen positivity without evidence of active viremia (negative hepatitis B DNA) they may still participate in the study, but should have hepatitis serologies and Hepatitis B DNA monitored periodically by the treating physician.
Patients who have hepatitis C (both reactive anti-hepatitis C virus [HCV] antibody and detectable HCV RNA) and hepatitis B (hepatitis B surface antigen [HBsAg] positive and anti-hepatitis B core [HBc]-total positive), may be enrolled, provided their total bilirubin: =< . x institutional upper limit of normal (ULN) AST (SGOT)/ALT (SGPT): =< . x institutional upper limit of normal
Patients who are human immunodeficiency virus (HIV) positive but have no prior acquired immune deficiency syndrome (AIDS)-defining illness and have cluster of differentiation (CD) cells of at least /mm^ are eligible; HIV-positive patients must not have multi-drug resistant HIV infection or other concurrent AIDS-defining conditions; patients must not be seropositive for hepatitis B (hepatitis B surface antigen positive or anti-hepatitis B core antigen positive) or seropositive for hepatitis C (anti-hepatitis C antibody positive); however, patients who are immune to hepatitis B (anti-hepatitis B surface antibody positive) are eligible (e.g. patients immunized against hepatitis B)
Seronegative for hepatitis B antigen, positive hepatitis B tests can be further evaluated by confirmatory tests, and if confirmatory tests are negative, the patient can be enrolled
Active hepatitis B as defined by seropositivity for hepatitis B surface antigen; or patients with positive hepatitis B core antibody titers
Adequate performance status (?  Karnofsky scale) with an estimated life expectancy\n             of at least  months\n\n             --Documented negative hepatitis B screen, per NCCN guidelines (hepatitis B surface\n             antigen/antibodies, core antigen/antibodies, hepatitis B e-antigen)
Known HIV positive or active hepatitis B or C, or presence of hepatitis B surface\n             antigens or presence of hepatitis C antibody
Presence of hepatitis B surface antigen (HbsAg)
Hepatitis B surface antigen (HBsAg) positive or hepatitis C antibody positive with elevated liver transaminases; all patients with chronic active hepatitis (including those on treatment) are ineligible
DONOR: Positive screening test for transfusion-transmissible infection in accordance with DTM or NMDP donation standards, including HIV-positive, hepatitis B surface antigen (HBsAg) positive or hepatitis C antibody positive
Negative for hepatitis B, or if infected with hepatitis B, receiving anti-hepatitis B therapy; all participants will be required to be screened for hepatitis B and C; per Infectious Disease Society of America (IDSA) and American Association for the Study of Liver Diseases (AASD) guidelines, those participants that show no immunity, defined by the lack of hepatitis B surface antibody, and show evidence of chronic infection (i.e. hepatitis B surface antigen positive [HBsAg+], hepatitis B core antibody positive [HBcore+], hepatitis surface antibody negative [HBsAB-]) will be required to be on anti-hepatitis B therapy, during the study, in order to be eligible; participants will be permitted to enroll in the study provided liver function tests meet criteria, and there is no evidence of cirrhosis; the exact hepatitis B therapy will be at the discretion of the infection disease specialist or investigator; however all participants who present with acute hepatitis B or show normal transaminases and are HBsAg+ and immunoglobulin (Ig)M+ for hepatitis core antigen will not be eligible for trial enrollment; participants who are hepatitis C antibody positive, with or without a positive hepatitis C RNA level, will be permitted to enroll in the study provided liver function tests meet criteria, and have no evidence of cirrhosis; participants diagnosed with hepatitis C less than  months from trial enrollment, will be considered to have acute hepatitis C and will be excluded from study unless hepatitis (hep) C viral load is undetectable
Participants with viral hepatitis who do not meet the criteria will not be eligible; all participants who present with acute hepatitis B including those with normal transaminases who are HBsAg+ and IgM + for hepatitis core antigen will not be eligible; participants who are hepatitis B core antibody positive are eligible only if they start or are on prophylactic therapy; a hepatitis B viral load should be confirmed negative on all participants who are hepatitis B core antibody positive, but hepatitis B antigen negative; participants refusing to take any anti-hepatitis B therapy during study will also be excluded; participants diagnosed with hepatitis C are eligible if they meet criteria
Chronic active hepatitis B; patient may be hepatitis B core antibody positive; for patients with concomitant positive hepatitis B surface antigen, patient will require a hepatology consultation; the risk/benefit profile of transplant and hepatitis B will be discussed with the patient and eligibility determined by the principal investigator and LAI
Positive test for Hepatitis B virus surface antigen or Hepatitis C antibody (except for subjects with hepatocellular carcinoma)
Subject who tests positive for hepatitis B surface antigen (HBVsAg) or hepatitis C RNA indicating acute or chronic infection except for subjects with hepatocellular carcinoma;
Positive Hepatitis B surface antigen test
Subjects with a history of Hepatitis B or C are eligible on the condition that subjects have adequate liver function as defined by the protocol and are hepatitis B surface antigen negative and/or have undetectable HCV RNA.
Positive for hepatitis B surface antigen (HBsAg), total hepatitis B core antibody (HBcAb), or hepatitis C virus (HCV) antibody at screening
Active hepatitis B infection as determined by hepatitis B surface antigen.
Hepatitis B surface antigen (HBsAg) positive
Known to be positive for hepatitis B by surface antigen expression and hepatitis B core antibody
Hepatitis B surface Antigen (HBsAg) positive
Known hepatitis B surface antigen seropositive, or known or suspected active hepatitis C infection. Note: Participants who have isolated positive hepatitis B core antibody (that is, in the setting of negative hepatitis B surface antigen and negative hepatitis B surface antibody) must have an undetectable hepatitis B viral load.
Positive for hepatitis B surface antigen (HBsAg), total hepatitis B core antibody (HBcAb), or hepatitis C virus (HCV) antibody at screening
Presence of positive test results for hepatitis B (hepatitis B surface antigen [HbsAg] and/or total hepatitis B core antibody [anti-HBc]) or hepatitis C (hepatitis C virus [HCV] antibody)
Active infection requiring therapy, positive tests for Hepatitis B surface antigen or Hepatitis C ribonucleic acid (RNA) except in patients with HCC, who meet the following criteria:
Patients with active hepatitis B defined by hepatitis B surface antigen positivity or core antibody positivity in the presence of hepatitis B DNA are not eligible for this study; patients with a positive hepatitis B core antibody but with negative hepatitis B DNA may participate, but must have hepatitis serologies and hepatitis B DNA monitored periodically by the treating physician\r\n* Intravenous immunoglobulin (IVIG) can cause a false positive hepatitis B serology; if patients receiving routine IVIG have core antibody or surface antigen positivity without evidence of active viremia (negative hepatitis B DNA) they may still participate in the study, but should have hepatitis serologies and hepatitis B DNA monitored periodically by the treating physician
Active hepatitis B, defined by a positive test for hepatitis B surface antigen [HBsAg] or prior history of hepatitis B, defined by presence of antibodies to hepatitis B core antigen [anti-HBc], regardless of hepatitis B surface antibody [anti-HBs] status; active hepatitis C or prior history of hepatitis C (anti-HCV positive), except in the setting of a sustained virologic response (SVR), defined as aviremia  weeks after completion of antiviral therapy. If hepatitis C virus (HCV) antibodies are detected, an HCV RNA test for viral load by polymerase chain reaction (PCR) should be performed at least  weeks after completion of antiviral therapy to rule out active infection Exclusion Criteria for Crossover:
Positive hepatitis B virus (HBV) surface antigen, or core antibody; and known or suspected active hepatitis C virus (HCV) infection, for the idelalisib arm; on the ibrutinib arm, patients with positive hepatitis B surface antigen may be appropriately treated and enrolled on this study as long as their HBV deoxyribonucleic acid (DNA) / viral load is undetectable; patients positive for hepatitis B (hepB) core antibody and negative for surface antigen are eligible for the ibrutinib arm, as are patients with hepatitis C
Active infection; positive for hepatitis B surface agent (HbsAg), total hepatitis B core antibody (HBcAb), or hepatitis C virus (HCV) antibody at screening; known history of HIV positive status, progressive multifocal leukoencephalopathy (PML), autoimmune disease
Patient is hepatitis C virus (HCV) antibody (Ab) positive or hepatitis B surface antigen (HBSAg) positive
Positive hepatitis B (hepatitis B surface antigen and antibody) and/or hepatitis C (hepatitis C antibody test) as indicated by serologies conducted =<  months prior to starting study if liver function tests are outside of the normal institutional range\r\n* NOTE: patients with hepatitis B or C serologies indicating active infection without known active disease must meet the eligibility requirements for ALT, AST, total bilirubin, INR, PTT, and alkaline phosphatase on at least two consecutive occasions, separated by at least  week
Positive Hepatitis B surface antigen test
Patients with a history of alcohol abuse, chronic hepatitis, or other chronic liver disease (other than direct CLL liver involvement); NOTE: chronic hepatitis includes active infection with hepatitis B or C; all patients will be tested for hepatitis C virus antibodies (HCV Ab) and hepatitis B surface antigen (HBsAg) at screening; patients with a positive result for HBsAg or HCV Ab will be excluded from enrolling in this study
Known seropositivity to human immunodeficiency virus (HIV), current acute or chronic hepatitis B (hepatitis B surface-antigen positive), hepatitis C, cirrhosis or evidence of decompensated liver disease. Patients with resolved Hepatitis B can be included.
Active hepatitis B as defined by hepatitis B surface antigen positivity, unless able to start dual anti-hepatitis B (HepB) therapy, or already on dual anti-HepB therapy
Patients who are positive for hepatitis B core antibody, but negative for the hepatitis B surface antigen, should be on lamivudine  mg daily until at least  months post-transplant
Known hepatitis B surface antigen seropositive or known or suspected active hepatitis C infection\r\n* Note: Patients who have isolated positive hepatitis B core antibody (i.e., in the setting of negative hepatitis B surface antigen and negative hepatitis B surface antibody) must have an undetectable hepatitis B viral load; patients who have positive hepatitis C antibody may be included if they have an undetectable hepatitis C viral load
Active hepatitis B infection as determined by test for hepatitis B surface antigen.
Prior, current, or chronic hepatitis B or hepatitis C infection, positive result for hepatitis C virus antibodies (HCV Ab) or hepatitis B surface antigen (HBsAg) or hepatitis B core antibodies (HBcAb)
HIV infection or active hepatitis B (defined as hepatitis B surface antigen positive) or C (defined as hepatitis C antibody positive)
Known human immunodeficiency virus (HIV) positive, or active hepatitis A, hepatitis B or hepatitis C; if hepatitis B surface antigen positive or B core antibody positive must have normal liver function tests and be willing and able to take anti-hepatitis medication such as lamivudine or equivalent
Consult with a physician experience in care and management of subjects with hepatitis B to manage/treat subjects who are anti-hepatitis B core antibody (HBc) positive
Patients with known hepatitis B surface antigen (HBsAg) positive hepatitis B virus (HBV) infection; patients with prior history of hepatitis B infection, but immune, with only immunoglobulin G (IgG) hepatitis core antibody positive (HBcAb +) must receive anti-viral prophylaxis (e.g., lamivudine  mg orally [PO] daily) for at least  week prior to cycle  and throughout induction and continuation therapy and for at least  months after the last brentuximab vedotin dose; in addition, consultation with a hepatologist is recommended
Active Hepatitis B infection as determined by test for hepatitis B surface antigen.
Chronic active hepatitis B infection; patients may be hepatitis B core antibody positive but must be surface antigen negative and without active evidence of disease
Known hepatitis B antigen (Ag) positive (this includes hepatitis B core Ag and hepatitis B surface Ag positive patients,) hepatitis C antibody positive patients
Presence of positive test results for Hepatitis B surface antigen (HBsAg); antibody to hepatitis B core antigen [anti-HBc]) with detectable viral load (positive hepatitis B virus [HBV] deoxyribo-nucleic acid [DNA]) or Hepatitis C
Negative tests for HIV antibodies, Hepatitis B surface antigen, and hepatitis C antibodies.
Active hepatitis B as defined by seropositivity for hepatitis B surface antigen or positive hepatitis B core antibody. Subjects with hepatitis C antibody will be eligible provided that they do not have elevated liver transaminases
Chronic active hepatitis B; patients may be hepatitis B core antibody positive; for patients with concomitant positive hepatitis B surface antigen, patient will require a hepatology consultation; the risk/benefit profile of transplant and hepatitis B will be discussed with the patient and eligibility determined by the principal investigator
Active hepatitis B or C (defined as positive hepatitis B surface antigen, hepatitis C antibody)
Subject has a known history of a positive test for hepatitis B surface antigen or hepatitis C antibody.
A positive Hepatitis B surface antigen or Hepatitis C test result at screening. Historical local data will be acceptable if it the test was done within one month before start of HSCT conditioning and not more than  months before study visit .
DONOR: Evidence of prior hepatitis B infection as evaluated by hepatitis B surface antigen (HBsAg), total hepatitis B core antibody (anti-HBc immunoglobulin [Ig]M and IgG) and hepatitis B surface antibody (anti-HBsAb); participants demonstrating any one of the following will be excluded:\r\n* positive hepatitis B surface antigen (HBsAg) or \r\n* positive anti-HBc IgM\r\n* positive anti-HBc IgG
Active evidence of hepatitis B or C infection; hepatitis B surface antigen positive
Active hepatitis B or C infection as defined by seropositivity for hepatitis B (hepatitis B surface antigen [HbsAg]) or hepatitis C (hepatitis C antibody) and elevated liver transaminases (defined as above the ULN per the institution normal ranges)
Prior, current, or chronic hepatitis B or hepatitis C infection, positive result for hepatitis B surface antigen (HBsAg) or hepatitis B core antibody (HBcAb) or hepatitis C virus antibodies (HCV Ab)
All subjects must be screened for hepatitis B and C infection; subjects must either have no history of hepatitis B or C, or must meet the following criteria in order to e eligible:\r\n* Hepatitis B: Subjects infected with hepatitis B must receive anti-hepatitis B therapy; per Infectious Diseases Society of America (IDSA) and American Association for the Study of Liver Diseases (AASLD) guidelines, subjects that show no immunity, defined by the lack of hepatitis B surface antibody, and show evidence of chronic infection (i.e. hepatitis B surface antigen positive [HBsAg+], hepatitis B core antibody positive [HB core AB +], hepatitis B surface antibody negative [HBsAB-]) must be on anti-hepatitis B therapy throughout the study in order to be eligible; the exact hepatitis B therapy is at the discretion of the infection disease specialist or investigator; all patients diagnosed with hepatitis B must also meet the liver function test criteria listed above and have no evidence of cirrhosis; however, all patients who present with acute hepatitis B, or who show normal transaminases but are HBsAg+ and immunoglobulin M positive (IgM+) for hepatitis B core antigen, are ineligible\r\n* Hepatitis C: Subjects, who are hepatitis C antibody positive, with or without a positive hepatitis C ribonucleic acid (RNA) level, must meet the liver function test criteria listed above and have no evidence of cirrhosis; patients diagnosed with hepatitis C less than  months before enrollment will be considered to have acute hepatitis C and will be ineligible unless the hepatitis C viral load is undetectable
Hepatitis B surface antigen (HBsAg) positive or hepatitis C antibody positive with elevated liver transaminases; all patients with chronic active hepatitis (including those on antiviral therapy) are ineligible
Known hepatitis B surface antigen and/or positive hepatitis C antibody and presence of hepatitis C RNA.
A positive test for hepatitis B surface antigen (HBsAg).
Positive hepatitis B surface antigen (HBsAg) results
Actively infected with or chronic carriers of hepatitis B virus (HBV) as demonstrated by positive hepatitis B core antibody (HbcAb) or hepatitis B surface antigen (HbsAg). (Patients who are sero-positive only, i.e., surface antibody positive [HbsAb], are permitted).
Presence of positive test results for hepatitis B surface antigen or hepatitis C virus (HCV) antibody
Known hepatic cirrhosis, hepatitis B surface antigen-positive status, or suspected active hepatitis C infection. Note: Participants who have isolated positive hepatitis B core antibody (that is, in the setting of negative hepatitis B surface antigen and negative hepatitis B surface antibody) must have an undetectable hepatitis B viral load.
Hepatitis B or C seropositivity (except for hepatitis B with negative surface antigen and hepatitis B viral load)
Actively infected with or chronic carriers of hepatitis B virus as demonstrated by positive hepatitis B core antibody or hepatitis B surface antigen. (Patients who are seropositive only, i.e. surface antibody positive [HbsAb], are permitted)
Patients with known human immunodeficiency virus (HIV), hepatitis B or hepatitis C (active or carriers) are not eligible; this includes all patients with a positive hepatitis C antibody, hepatitis B surface antigen, or hepatitis B core antibody; previously vaccinated patients with positive hepatitis B surface antibody are eligible
Presence of hepatitis B surface antigen (HBsAg), positive hepatitis C antibody test result at screening or within  months prior to first dose of study treatment.
Positive blood screen for hepatitis A IgM, hepatitis C antibody, hepatitis B surface antigen, or HIV-, - antibody
Positive hepatitis B antigen (HBsAg) or hepatitis C serology (HCV) tests; note: hepatitis B surface antigen (HbsAg) and antibody to Hepatitis B core (anti-HBc); hepatitis C antibody; all patients must be screened prior to registration; those patients who have evidence of chronic or acute infection with either hepatitis B or C may not be treated on this protocol
Presence of hepatitis B surface antigen (HbsAg)
Chronic active hepatitis B; patient may be hepatitis B core antibody positive; for patients with concomitant positive hepatitis B surface antigen, patient will require a hepatology consultation; the risk/benefit profile of transplant and hepatitis B will be discussed with the patient and eligibility determined by the principal investigator and protocol chairperson
DONOR: Donors must be HIV negative, hepatitis B surface antigen negative, and hepatitis C antibody negative; donors with a history of hepatitis B or hepatitis C infection may be eligible; however, eligibility determination of such patients will require a hepatology consultation; the risk/benefit of the transplant and the possibility of transmitting hepatitis will be discussed with the patient and eligibility will then be determined by the principal investigator
Known positive HIV, Hepatitis B surface antigen or Hepatitis C antibody.
Active hepatitis B or hepatitis C infection (hepatitis B surface antigen testing required)
History of infection with the hepatitis B and/or C viruses or positive hepatitis B virus surface antigen and hepatitis C virus antibody
Known hepatitis B (they test positive for the presence of at least one of the following three markers in blood (to be evaluated at screening): hepatitis B surface antigen (HBsAG), antibodies against hepatitis B core antigen (anti-HBc), or hepatitis B viral load (hepatitis B virus [HBV] deoxyribonucleic acid [DNA]), or known active hepatitis C infection
Subject has a known history of a positive test for hepatitis B surface antigen (HBsAg) or hepatitis C antibody (anti-HCV).
Current or chronic hepatitis B or hepatitis C infection (as detected by positive testing for Hepatitis B surface Antigen [Hbs Ag] or antibody to Hepatitis C virus [anti HCV] respectively); patients must be tested for Hepatitis B surface antigen and anti-HCV =<  days prior to registration
Active hepatitis B infection as demonstrated by test for hepatitis B surface antigen. Subjects who are hepatitis B surface antigen negative but are hepatitis B core antibody positive must have undetectable hepatitis B DNA and receive prophylaxis against viral reactivation.
Chronic hepatitis B or C infection (e.g. hepatitis B surface antigen [Ag] positive or detectable viral load for hepatitis B or C); patients with prior evidence of hepatitis B or C without active infection are eligible
Documented virology status of hepatitis, as confirmed by screening hepatitis B surface antigen (HBsAg), antibody to hepatitis B core antigen (anti-HBc), and/or anti-hepatitis C virus (anti-HCV)
Has known seropositivity for HIV or hepatitis C antibody, or known to be hepatitis B surface antigen positive (testing for these serologic markers is not required for enrollment in this protocol)
Known active hepatitis B or C; patients must have a negative test for hepatitis B surface antigen, hepatitis B core antibody and hepatitis C antibody within  weeks prior to starting study drug
Human immunodeficiency virus (HIV), hepatitis B (hepatitis B core antibody [HBcAb] positive but hepatitis B surface antigen [HBsAg] negative with undetectable viral load are eligible), or hepatitis C infection
Subjects with positive test for Hepatitis B surface (HBS-Ag) or Hepatitis B core (HBc)antigen
Active HIV, HBV, HCV or HTLV / infection (due to increased risk of complications during lymphodepleting regimen and confounding effects on the immune system). Active hepatitis B or C infection is defined by seropositive for hepatitis B surface antigen (HbSAg) or hepatitis C antibody.
Active or chronic hepatitis B infection (defined as having a positive hepatitis B surface antigen [HBsAg] test at screening); subject with past or resolved hepatitis B infection (defined as having a negative HBsAg test and positive antibody to hepatitis B core antigen test) are eligible; hepatitis B viral DNA must be obtained in subjects with positive hepatitis B core antibody prior to first treatment start
Active hepatitis B (defined as having a positive hepatitis B surface antigen [HBsAg] test at screening) or hepatitis C
Known history of hepatitis B or hepatitis C infection or known positive test for hepatitis B surface antigen, hepatitis B core antigen, or hepatitis C polymerase chain reaction.
History of any chronic hepatitis including alcoholic, non-alcoholic steatohepatitis (NASH), drug related, autoimmune, chronic viral positive tests for hepatitis B virus surface antigen (HBsAg), hepatitis B core antibody (anti-HBc) in the absence of hepatitis B surface antibody (anti-HBs), or a positive hepatitis C (HCV) viral load; these patients are excluded