Chronic concomitant treatment with strong inhibitors of cytochrome P, family , subfamily A, polypeptide (CYPA) inhibitors must discontinue the drug for days prior to registration on the study Concomitant medications:\r\n* Chronic concomitant treatment with strong inhibitors of cytochrome P, family , subfamily A, polypeptide (CYPA) is not allowed on this study; patients on strong CYPA inhibitors must discontinue the drug for days prior to registration on the study\r\n* Chronic concomitant treatment with strong CYPA inducers is not allowed; patients must discontinue the drug days prior to the start of study treatment\r\n* Patients requiring anticoagulation must be on stable dose of medication prior to registration Requires chronic treatment with strong cytochrome P family , subfamily A, polypeptide (CYPA) inhibitors Use of strong cytochrome P, family , subfamily A (CYPA) inhibitors and inducers Require treatment with strong cytochrome P family subfamily A (CYPA) inhibitors Requires treatment with a strong cytochrome P modulators (cytochrome P, family , subfamily A [CYPA] inhibitor and/or CYPA inducers) Requires chronic treatment with strong cytochrome P, family , subfamily A (CYPA) inhibitors Administration of strong/potent cytochrome P, family , subfamily A (CYPA) inhibitors or inducers within days prior to the first dose of study treatment and while on treatment with alectinib except for oral corticosteroids up to mg of prednisone equivalent per day Requires treatment with strong cytochrome P, family , subfamily A (A) (CYPA) inhibitors Requires chronic treatment with strong cytochrome P, family , subfamily A (CYPA) inhibitors Relapsed/refractory MCL: Requires treatment with strong cytochrome P, family , subfamily A, polypeptide / (CYPA/) inhibitors Chronic concomitant treatment with strong cytochrome P, family , subfamily C, polypeptide (CYPC) inhibitors is not allowed; patients must discontinue the drug >= days prior to registration Chronic concomitant treatment with strong cytochrome P, family , subfamily A, polypeptide (CYPA) inhibitors is not allowed; patients must discontinue the drug >= days prior to registration Chronic concomitant treatment with strong inhibitors of cytochrome p, family , subfamily a, polypeptide gene (CYPA) is not allowed on this study; patients on strong CYPA inhibitors must discontinue the drug for days prior to registration on the study Concomitant medications:\r\n* Chronic concomitant treatment with strong inhibitors of cytochrome P, family , subfamily A, polypeptide (CYPA) inhibitors must discontinue the drug for days prior to registration on the study for patients with NF mutation enrolled to GSK\r\n* Chronic concomitant treatment with strong CYPA inducers is not allowed; patients must discontinue the drug days prior to the start of study treatment for patients with NF mutation enrolled to GSK Use of strong cytochrome P family subfamily A member (A) (CYPA) inhibitors or strong CYPA inducers within weeks before the start of study treatment Patients taking medications known to be strong cytochrome P, family , subfamily A (CYPA) inhibitors Patients who require treatment with strong cytochrome P family , subfamily A (CYPA) inducers Requires treatment with strong cytochrome P, family , subfamily A (CYPA) inhibitors Requires treatment with strong cytochrome P family , subfamily A, polypeptide / (CYPA/) inhibitors Chronic concomitant treatment with strong inhibitors of cytochrome P, family , subfamily A, polypeptide (CYPA) is not allowed on this trial; patients on strong CYPA inhibitors must discontinue the drug days prior to the start of study treatment Patients taking medications known to be strong cytochrome P, family , subfamily A (CYPA) inhibitors Patients requiring chronic treatment with strong cytochrome P family , subfamily A (CYPA) inhibitors cannot be treated with ibrutinib but idelalisib would be an option Chronic concomitant treatment with strong inhibitors of cytochrome P, family , subfamily A, polypeptide (CYPA) is not allowed on this trial; patients on strong CYPA inhibitors must discontinue the drug days prior to the start of study treatment Subjects have received potent cytochrome P, family , subfamily A (CYPA) inhibitors within days prior to the initiation of study treatment No concurrent strong cytochrome P A inhibitors Requires chronic treatment with strong cytochrome P, family , subfamily A (CYPA) inhibitors