Hx of drug-related anaphylactic reactions, severe allergic reactions related to drug; active diagnosis of uncontrolled airway hyperactivity, uncontrolled asthma, or asthma requiring oral corticosteroids. Moderate or severe persistent asthma, or a history of asthma within the last years, or currently has uncontrolled asthma of any classification Subject has known moderate or severe persistent asthma within the past years or currently has uncontrolled asthma of any classification\r\n* Subjects who currently have controlled intermittent asthma or controlled mild persistent asthma are allowed in the study Patients must not have aspirin sensitive asthma Known chronic obstructive pulmonary disease (COPD) (defined as a forced expiratory volume in second [FEV] < % of predicted normal), persistent asthma, or a history of poorly controlled asthma within the last years (controlled intermittent asthma or controlled mild persistent asthma is allowed) Severe asthma. Currently being treated with bronchodilators or corticosteroids or known to have active asthma. This will not include patients who suffered from asthma as a child and outgrew it. Known moderate or severe persistent asthma within the past years, or uncontrolled asthma of any classification. Note that subjects who currently have controlled intermittent asthma or controlled mild persistent asthma are allowed to participate in the study. History of asthma that is nonsteroidal anti-inflammatory drug (NSAID)-induced or with asthma that is classified as mild-persistent or worse (based on symptoms occurring more than days per week) Known severe hypersensitivity reactions to monoclonal antibodies (Grade ?), any history of anaphylaxis, or uncontrolled asthma (ie, or more features of partially controlled asthma Global Initiative for Asthma ) Patients with a history of asthma will be excluded Known moderate or severe persistent asthma within the past years, or uncontrolled asthma of any classification Criteria Known moderate or severe persistent asthma within the past years Subject has known moderate or severe persistent asthma within years, or currently has uncontrolled asthma of any classification; (Note that subjects who currently have controlled intermittent asthma or controlled mild persistent asthma are allowed in the study) Subject has known moderate or severe persistent asthma within the past years, or currently has uncontrolled asthma of any classification. NOTE: subjects who currently have controlled intermittent asthma or controlled mild persistent asthma are allowed in the study Known moderate or severe persistent asthma within the past years or currently has uncontrolled asthma of any classification Participant has known chronic obstructive pulmonary disease (COPD) (defined as a forced expiratory volume in second [FEV] <% of predicted normal), persistent asthma, or a history of asthma within the last years (controlled intermittent asthma or controlled mild persistent asthma is allowed) Has moderate or severe persistent asthma within the past years or uncontrolled asthma of any classification. Known chronic obstructive pulmonary disease, persistent asthma, or a history of asthma within years Participant has known chronic obstructive pulmonary disease (COPD) (defined as a forced expiratory volume in second [FEV] <% of predicted normal), known moderate or severe persistent asthma within the last years or currently has uncontrolled asthma of any classification (controlled intermittent asthma or controlled mild persistent asthma is allowed) History of asthma Participant has known chronic obstructive pulmonary disease (COPD) with a Forced Expiratory Volume in second (FEV) less than (<) % predicted normal. Note that FEV testing is required for participants suspected of having COPD and participants must be excluded if FEV <% b) Participant has known moderate or severe persistent asthma within years (see Attachment : NHLBI table of asthma severity), or currently has uncontrolled asthma of any classification. (Note that participants who currently have controlled intermittent asthma or controlled mild persistent asthma are allowed in the study) History of drug-related anaphylactic reactions or allergic reactions; subjects with an active diagnosis of uncontrolled airway hyperactivity, uncontrolled asthma, or asthma requiring oral corticosteroids will be excluded History of asthma Patients must not have uncontrolled asthma Asthma or other reactive airway disease No history of bronchial asthma or related bronchospastic conditions Participants with persistent asthma as defined by the National Heart, Lung, and Blood Institute. Participants with persistent asthma as defined by the National Heart, Lung, and Blood Institute Adult asthma Clinical diagnosis of asthma Adult asthma Participants with persistent asthma as defined by the National Heart, Lung, and Blood Institute Asthma, wheezing or breathing problems History of chronic asthma Patient must not have a history of allergy or bronchial asthma Uncontrolled asthma or asthma requiring oral corticosteroids.