Patients must be deemed able to comply with the treatment plan and follow-up schedule Patients who are able to comply with the protocol follow-up schedule Able to understand and voluntarily sign the ICF and able to comply with the study visit schedule and the other protocol requirements. Patients must be deemed able to comply with the treatment plan and follow-up schedule Must be able to comply with the treatment plan and follow-up schedule Willingness to give consent and comply with all study-related evaluations and treatment schedule; and Ability to comply with the treatment schedule Ability and willingness to obtain all required scans per study schedule Able to comply with the treatment schedule Willing to comply with proposed visit and treatment schedule Ability to comply with the treatment schedule Able to comply with the treatment schedule Patient is unable or unwilling to provide written informed consent or comply with follow-up schedule Willingness to follow the requirements of the intravenous ascorbic acid program schedule Inability to give consent or adhere to follow-up schedule Willing and able to comply with follow-up schedule Willing and able to give written informed consent and comply with study visit schedule Patients must comply with the treatment plan and follow-up schedule. Willing and able to give written informed consent and comply with study visit schedule. Willingness to follow study visit schedule, pregnancy precautions and other protocol requirements. Patient must be able to give informed consent and comply with the treatment protocol and follow-up plan. Patients must be willing and able to sign the informed consent form, and to follow the study visit schedule and other protocol requirements. Inability to provide informed consent or to comply with the schedule of office and treatment visits Able to comply with the treatment schedule Unable to comply with the study follow-up schedule Willing to give consent and comply with study-related evaluation and treatment schedule; and Willing and able to comply with post-operative treatment protocol and follow-up visit schedule. Able to comply with study visit schedule and assessments. Patient is unwilling or unable to comply with the follow-up schedule Unable to commit to intervention schedule ( weekly group meetings) Chemotherapy treatment schedule < weeks Able to commit to a long term follow-up schedule Patients must be deemed able to comply with the treatment plan and follow-up schedule Unwilling or unable to comply with the follow-up schedule Cannot commit to the intervention schedule Inability to commit to the intervention schedule Patients who are not planning to adhere to the required follow up schedule as outlined in this protocol Patient is not likely to comply with the follow-up evaluation schedule Patients who are not planning to adhere to the required follow up schedule as outlined in this protocol Patient is not likely to comply with the follow-up evaluation schedule