Has inadequate venous access and/or contraindications to leukapheresis Subject is fit for leukapheresis and has adequate venous access for the cell collection. Major surgery within days of day (does not include central venous access or shunts) Poor peripheral venous access Adequate central venous access potential Central venous access, such as a Portacath or Hickman Line Adequate venous access (for leukapheresis and blood draws) At least days after minor surgery (such as central venous access) or biopsy and recovery to =< grade treatment-related toxicity Research participant must have appropriate venous access Poor venous access for study drug administration Subject has sufficient venous access to permit administration of study drug (for the IV cohorts), collection of pharmacokinetic samples and monitoring of safety laboratories. Have inadequate venous access for or contraindications to leukapheresis Must have adequate venous access for apheresis Subjects must not have inadequate venous access for or contraindications to leukapheresis Research participant must have appropriate venous access Research participant must have appropriate venous access If research participant is undergoing leukapheresis he/she must have appropriate venous access Have access via central line (e.g., portacath) RECIPIENT: Adequate central venous access potential Adequate central venous access potential Adequate intravenous (IV) access Poor or unsuitable venous access Poor venous access for study drug administration unless patient can use silicone based catheters Poor peripheral venous access Reliable venous access suitable for weekly study drug infusions Adequate central venous access potential Lack of peripheral venous or central venous access or any condition that would interfere with drug administration or collection of study samples Subject is fit for leukapheresis and has adequate venous access for the cell collection. Have insufficient peripheral venous access to permit completion of the study dosing and compliance with study phlebotomy regimen Subject either currently has central vascular access or is a candidate to receive central vascular access or peripheral vascular access for leukapheresis procedure. Adequate IV access Suitable venous access Inability to obtain venous access in the antecubital region to administer PHO or sedation for endoscopy procedures Must have adequate venous access for apheresis. Adequate IV access A vascular access device (port) or other central venous access for administration of chemotherapy is recommended Central venous access, such as a Portacath or Hickman Line Absence of central venous access for administration of the study drug Adequate central or peripheral vascular access for leukapheresis procedure Adequate venous access Adequate venous access Central venous access Subjects with sufficient vascular access to accommodate the RBCx procedure as determined by the medical staff responsible for obtaining intravenous access. Does the subject have adequate venous access? Central venous access Adequate venous access Suitable venous access Adequate venous access Subject is fit for apheresis and has adequate venous access for the cell collection. Do not have access to at least one intervention format History of difficult intravenous access Access to refrigerator or freezer Functioning Central Venous Access Device Patients who only have a totally implanted port as their central venous access will not be eligible for this study Access to devices that play DVDs Participant must have adequate venous or central access for irinotecan administration Inadequate venous access per assessment of treating health care provider No known problems with peripheral IV or central line access Inadequate venous access (a single antecubital or equivalent venous access sites are required for study drug injection) Adequate peripheral venous access or available central venous catheter access for radiopharmaceutical administration Presence of any indwelling line or drain. Note: Dedicated central venous access catheters such as a Port-a-Cath are permitted. Inadequate venous access Inadequate venous access per assessment of treating health care provider Inadequate venous access (two antecubital or equivalent venous access sites)